A5028578048- Rabies epidemiology and control
- Virology and Viral Diseases
- Microbial infections and disease research
- Viral Infections and Outbreaks Research
- Human-Animal Interaction Studies
- Poxvirus research and outbreaks
- Yersinia bacterium, plague, ectoparasites research
- Veterinary Equine Medical Research
- Veterinary Practice and Education Studies
- Primary Care and Health Outcomes
- Mental Health and Patient Involvement
- Bacillus and Francisella bacterial research
- Viral Infections and Vectors
- Data-Driven Disease Surveillance
- Health Policy Implementation Science
- Zoonotic diseases and public health
- Food Security and Health in Diverse Populations
- Gothic Literature and Media Analysis
- Diagnosis and Treatment of Venous Diseases
- Veterinary Medicine and Surgery
- Streptococcal Infections and Treatments
- Effects of Environmental Stressors on Livestock
- Health and Wellbeing Research
- Tendon Structure and Treatment
- School Health and Nursing Education
Worldwide Veterinary Service
2018-2025
University of the West of England
2022-2024
University Hospitals Bristol NHS Foundation Trust
2024
University Hospitals Bristol and Weston NHS Foundation Trust
2024
NIHR Bristol Biomedical Research Centre
2024
University of Bristol
2024
Roslin Institute
2018-2023
University of Edinburgh
2004-2023
Statens Serum Institut
2022
Federal Institute for Risk Assessment
2022
Abstract Dog-mediated rabies kills tens of thousands people each year in India, representing one third the estimated global burden. Whilst World Health Organization (WHO), for Animal (OIE) and Food Agriculture United Nations (FAO) have set a target dog-mediated human elimination by 2030, examples large-scale dog vaccination programs demonstrating remain limited Africa Asia. We describe development data-driven program from 2013 to 2019 Goa State, culminating 92% reduction monthly canine...
AimsTo investigate whether aneurysm shape and extent, which indicate a patient with ruptured abdominal aortic (rAAA) is eligible for endovascular repair (EVAR), influence the outcome of both EVAR open surgical repair.
Canine transmitted rabies kills an estimated 59,000 people annually, despite proven methods for elimination through mass dog vaccination. Challenges in directing and monitoring numerous remote vaccination teams across large geographic areas remain a significant barrier to the up-scaling of focal programmes sub-national national level. Smartphone technology (mHealth) is increasingly being used enhance coordination efficiency public health initiatives developing countries, however examples...
Over 20 000 people die from rabies each year in India. At least 95 % of contract an infected dog. Annual vaccination over 70 the dog population has eliminated both canine and human many countries. Despite having highest burden world, there have been very few studies which reported successful, large scale dogs Furthermore, Indian programmes not achieved high vaccine coverage. In this study, we utilised a catch-vaccinate-release approach programme 18 wards Ranchi, Following vaccination,...
An estimated 60,000 people die of rabies annually. The vast majority cases human develop following a bite from an infected dog. Rabies can be controlled in both and canine populations through widespread vaccination dogs. is particularly problematic Malawi, costing the country 13 million USD 484 deaths annually, with increasing paediatric incidence Blantyre City. Consequently, aim this study was to vaccinate minimum 75% all dogs within city during one month period. Blantyre’s 25...
Rabies has profound public health, social and economic impacts on developing countries, with an estimated 59,000 annual human rabies deaths globally. Mass dog vaccination is effective at eliminating the disease but remains challenging to achieve in India due high proportion of roaming dogs that cannot be readily handled for parenteral vaccination. Two methods could not injection were compared Goa, India; oral bait handout (OBH) method, where teams two travelled by scooter offering empty...
Introduction Dog vaccination against rabies is considered one of the most effective strategies at preventing human deaths from and a key strategy for eliminating dog-mediated deaths. Traditional approaches in Zambia rarely collect operational data to assess coverage inform subsequent campaigns. Methods Following mass campaigns rural (Itezhi tezhi) urban (Lusaka) communities, we evaluated achieved during characterized estimated dog population these communities. Results Herd immunity (i.e.,...
Abstract Veterinarians are custodians of animal welfare, ensuring practices remain current and effective in the face ever-changing demands profession. Continuing Professional Development (CPD) is essential for protecting however access to quality CPD a challenge many countries. India has one fastest growing veterinary industries globally, emphasising importance accessible opportunities that relevant this setting. This study used focus groups explore how Indian veterinarians identify CPD,...
Rabies is a devastating yet preventable disease that causes around 59,000 human deaths annually. Almost all rabies cases are caused by bites from rabies-infected dogs. A large proportion of these occur in Sub Saharan Africa (SSA). Annual vaccination at least 70% the dog population recommended World Health Organisation order to eliminate rabies. However, achieving such high coverage has proven challenging, especially low resource settings. Despite being logistically and economically more...
Rabies is an important neglected disease, which kills around 59,000 people a year. Over third of these deaths are in children less than 15 years age. Almost all human rabies Africa and Asia due to bites from infected dogs. Despite the high efficacy current vaccines, awareness about preventive healthcare often low endemic areas. It therefore common for educational initiatives be conducted conjunction with other control activities such as mass dog vaccination, however there few examples where...
As countries with endemic canine rabies progress towards elimination by 2030, it will become necessary to employ techniques help plan, monitor, and confirm elimination. Sequencing can provide critical information inform control vaccination strategies identifying genetically distinct virus variants that may have different host reservoir species or geographic distributions. However, many testing laboratories lack the resources expertise for sequencing, especially in remote rural areas where...
Dogs harbor numerous zoonotic pathogens, many of which are controlled through vaccination programs. The delivery these programs can be difficult where resources limited. We developed a dynamic model to estimate coverage and cost-per-dog vaccinated. considers the main factors that affect programs: dog demographics, effectiveness strategies, efficacy interventions cost. was evaluated on data from 18 representing eight countries. Sensitivity analysis performed for confinement strategies....
Free-roaming dogs (FRD) represent a large proportion of the canine population in India and are often implicated as source conflict with humans. However, objective data on attitudes perceptions local communities toward FRD lacking. This study collected baseline from 1141 households Goa, India, feeding practices assessed people's urban rural communities. Additionally, respondents identified problems caused by proposed potential solutions.The reported that 37% fed dog owners Hindus being most...
A retrospective cross-sectional study was used to analyse pyometra cases at five RSPCA Animal Hospitals across the UK from 2006 2011. total of 1728 were recovered a female dog outpatient caseload 78,469 animals, giving prevalence 2.2 per cent over period. There an annual increase in incidence within population, while elective ovariohysterectomy has declined. variations breed and age presentation. Bullmastiffs (P<0.0001), golden retrievers (P=0.001) dogue de Bordeaux (P=0.008)...
Abstract Background Rabies is a fatal but preventable viral disease, which causes an estimated 59 000 human deaths globally every year. The vast majority of rabies cases are attributable to bites from infected domestic dogs and consequently control in the dog population through mass vaccination campaigns considered most effective method eliminating disease. Achieving WHO target 70% coverage has proven challenging low-resource settings such as Sub Saharan Africa, lack public awareness about...
Significance Rabies is arguably the exemplar of One Health Agenda in which preventative health care one species can improve other species. Interrogation large epidemiology datasets offers potential to deliver initiatives a more efficient and cost-effective manner. However, real-life examples demonstrating this are limited. Here, we report real-time, data-driven approach cost effectiveness dog vaccination campaigns urban sub-Saharan African settings, eliminates need expensive door-to-door by...
Introduction: To achieve the global goal of canine-mediated human rabies elimination by 2030 there is an urgent need to scale-up mass dog vaccination activities in regions with large populations that are difficult access; a common situation much India. Oral may enable free-roaming dogs inaccessible parenteral vaccination, and considered promising complementary measure campaigns. WHO OIE have published detailed minimum requirements for vaccines baits be used this purpose, requiring must not...
Rabies is a devastating zoonotic disease causing nearly 60,000 deaths globally each year. The causes Malawi an economic loss of 13 million USD and kills almost 500 people annually. Domestic dogs are the main reservoir for rabies vaccinating over 70% dog population most efficient method to reduce its incidence in both humans canines. However, achieving such coverages often difficult depend on many geospatial factors. Rural pastoral regions considered vaccinate efficiently due low densities,...
Oral rabies vaccination (ORV) can increase coverage among dogs that are inaccessible to parenteral (i.e., dogs). Because bait uptake differ according the attractant used and dog characteristics, we evaluated proportion of time using three formulations. We looked for associations between characteristics (temperament, age, body condition) assessed efficiency these formulations, as measured by number vaccinated per hour. A total 356 baits were offered free roaming in urban peri-urban districts...
We conducted a cross-sectional survey to better understand the barriers attendance at canine rabies vaccination campaigns in Haiti. A structured community-based questionnaire was over 15-day period during May–June 2017, focused on socio-economic status correlated with participation campaigns. Questions phrased as bidding game were asked determine individuals' willingness pay (WTP) for dog and walk (WTW) fixed-point The Kaplan–Meier estimator applied relationships between variables. Logistic...
Despite the disease's long history, little progress has been made toward a treatment for rabies. The prognosis patient recovery remains dire. For any prospect of survival, patients require aggressive critical care, which physicians in rabies endemic areas may be reluctant or unable to provide given cost, clinical expertise required, and uncertain outcome. Systematic research into combination therapies is further hampered by sporadic occurrence cases. In this Perspective, we examine case One...
Rabies is an endemic, highly fatal, and vaccine-preventable disease with severe socio-economic implications. Most (99%) human rabies cases are transmitted through dog bites. Children under 15 years account for 40% of all bite victims 35-50% deaths. awareness among this vulnerable group critical to prevention. However, there a paucity data on pupils 15. Hence, study assessed the attitude towards canine in Kwara state Nigeria. The was conducted as cross-sectional survey 1,388 across using...