A5001040566- Rabies epidemiology and control
- Virology and Viral Diseases
- Viral Infections and Outbreaks Research
- Microbial infections and disease research
- Poxvirus research and outbreaks
- Streptococcal Infections and Treatments
- Mycotoxins in Agriculture and Food
- Food Safety and Hygiene
- Vaccine Coverage and Hesitancy
- Yersinia bacterium, plague, ectoparasites research
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
Kenya Medical Research Institute
2019-2024
Washington State Department of Health
2023
Washington State University
2023
Tens of thousands people die from dog-mediated rabies annually. Deaths can be prevented through post-exposure prophylaxis for who have been bitten, and the disease eliminated dog vaccination. Current use saves many lives, but availability remains poor in rabies-endemic countries due to high costs, access, supply.
<ns4:p>Genomic surveillance is an important aspect of contemporary disease management but has yet to be used routinely monitor endemic transmission and control in low- middle-income countries. Rabies almost invariably fatal viral that causes a large public health economic burden Asia Africa, despite being entirely vaccine preventable. With policy efforts now directed towards achieving global goal zero dog-mediated human rabies deaths by 2030, establishing effective tools critical. Genomic...
As countries with endemic canine rabies progress towards elimination by 2030, it will become necessary to employ techniques help plan, monitor, and confirm elimination. Sequencing can provide critical information inform control vaccination strategies identifying genetically distinct virus variants that may have different host reservoir species or geographic distributions. However, many testing laboratories lack the resources expertise for sequencing, especially in remote rural areas where...
Genomic surveillance is an important aspect of contemporary disease management but has yet to be used routinely monitor endemic transmission and control in low- middle-income countries. Rabies almost invariably fatal viral that causes a large public health economic burden Asia Africa, despite being entirely vaccine preventable. With policy efforts now directed towards achieving global goal zero dog-mediated human rabies deaths by 2030, establishing effective tools critical. data can provide...
Rabies kills tens of thousands people every year despite being entirely vaccine preventable. Key global health actors have launched a country-driven plan to achieve zero human deaths from dog-mediated rabies by 2030 worldwide. This partnership has recently been strengthened Gavi, the Vaccine Alliance's decision invest in vaccines for post-exposure prophylaxis (PEP). While nation states are key elimination, importance Gavi's role cannot be understated. Unlike any other actor, Gavi can...
Prompt provision of post-exposure-prophylaxis (PEP) including vaccines and rabies immunoglobulin (RIG) to persons bitten by suspect rabid dogs is a key strategy eliminating human deaths from dog-mediated in Kenya 2030. We assessed the availability, forecasting supply chain logistics for PEP Kenya, compared with system used expanded program immunization (routine vaccines). Semi-structured questionnaires capturing data on forecasting, procurement, distribution, cold storage, monitoring...
<ns4:p><ns4:bold>Background:</ns4:bold> Domestic dogs transmit 99% of the estimated 59,000 human rabies deaths occurring globally annually. To achieve global target zero from by 2030, effective mass dog vaccination campaigns that break transmission cycles in populations are required. This study describes design a health and demographic surveillance established within Western Kenya. Using baseline data cohort study, we quantify parameters describe management practices relevant for...
Abstract Objective: Identifying factors that may influence aflatoxin exposure in children under 5 years of age living farming households western Kenya. Design: We used a mixed methods design. The quantitative component entailed serial cross-sectional interviews 250 to examine crop processing and conservation practices, household food storage consumption local understandings aflatoxins. Qualitative data collection included focus group discussions ( N 7) key informant 13) explore explanations...
<title>Abstract</title> <bold>Background: </bold>Rabies remains a major public health problem in low- and middle-income countries. However, human rabies deaths are rarely laboratory-confirmed, especially Africa. Here, we use virus sequence data to enhance investigations for series of 5 East Africa discuss the implications these at individual, healthcare, societal-level. <bold>Case presentation: </bold>The epidemiological context care cases is contrasting: three bite victims did not receive...