A5101575036- Iron Metabolism and Disorders
- Trace Elements in Health
- Hemoglobinopathies and Related Disorders
- Ergonomics and Human Factors
- Skin and Cellular Biology Research
- Heavy Metal Exposure and Toxicity
- Quality Function Deployment in Product Design
- Sympathectomy and Hyperhidrosis Treatments
- Protein Degradation and Inhibitors
- Infection Control and Ventilation
- Celiac Disease Research and Management
- Educational Reforms and Innovations
- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Neuroendocrine regulation and behavior
- Cancer and Skin Lesions
- Glycosylation and Glycoproteins Research
- Product Development and Customization
- Epigenetics and DNA Methylation
- Medical Research and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Child Nutrition and Water Access
- Neurological disorders and treatments
- Human-Animal Interaction Studies
- Quality and Supply Management
National Changhua University of Education
2024
Scripps Research Institute
2023
Zhejiang University
2019-2022
Fuzhou University
2022
Shanghai University of Traditional Chinese Medicine
2020
Shanghai Institute for Science of Science
2020
Hainan General Hospital
2020
Second Affiliated Hospital of Shantou University Medical College
2017-2018
Shantou University
2017-2018
First Affiliated Hospital of Anhui Medical University
2018
Transferrin receptor 1 (Tfr1) mediates the endocytosis of diferric transferrin in order to transport iron, and Tfr1 has been suggested play an important role hematopoiesis. To study hematopoiesis, we generated hematopoietic stem cell (HSC) specific knockout mice. We found that conditional mice reached full term but died within one week birth. Further analyses revealed Tfr1-deficient HSC had impaired development all progenitors except thrombocytes B lymphocytes. In addition, cells cellular...
This study explored an innovative design of a drain cover for dirt removal, deodorization, and pest control. The research methods used in this included analysis the literature, TRIZ method general design, application human factors engineering. Firstly, contradiction matrix was to find out corresponding principles invention analysis. Based on reference most drainage with rapid cleansing, insect-repellent properties, quick return designed, universal make cover. can be more widely allow users...
This study investigates the innovative design of a bicycle saddle by incorporating sustainable ergonomics, universal principles, and systematic innovation methods. Initially, literature related to its impact on human body during riding was analyzed. The TRIZ contradiction matrix then used identify relevant invention which served as references for saddle. Biomechanics human–machine system analysis within factors engineering were applied ensure is ergonomic user-friendly. features horizontally...
Acute myeloid leukemia (AML) is a genetically heterogeneous and frequently fatal malignancy. The ten-eleven translocation (TET)-mediated DNA demethylation known to be critically associated with AML pathogenesis. Through chemical compound screening, we find that the opioid receptor agonist, loperamide hydrochloride (OPA1), significantly suppresses cell viability. potential therapeutic effects of agonists, especially OPA1, are verified in cells vitro mouse human models vivo. OPA1-induced...
Abstract The polymorphism of PRKCB has been proven to be associated with systemic lupus erythematosus (SLE) in our previous study. We aimed investigate the relationship between expression mRNA and Disease Activity Index (SLEDAI) manifestations SLE. Quantitative reverse transcription polymerase chain reaction (RT‐PCR) was applied examine peripheral blood mononuclear cells 60 patients SLE 62 controls. Sequenom MassArray System used detect genotype SNP rs16972959. levels cases were...
Abstract We previously showed three‐dimensional (3D) reconstructed eccrine sweat glands have similar structures as native glands, but whether the 3D appropriately secrete fluid is still unknown. In this study, Matrigel‐embedded human gland cells or Matrigel alone were implanted into groin subcutis of nude mice. Ten weeks post‐implantation, images subcutaneously formed plugs, well footpads rats, pre‐ and post‐pilocarpine/normal saline ( NS ) injection acquired using a fat‐suppressed proton...
Harmony, an inherent value concept and a lofty ideal of the Chinese nation as well final aim well-being in TCM, is quite characteristic philosophical thought ancient culture, which infiltrated different aspects people's life penetrated various TCM well-being.Harmony reflected relations between nature human, mind physique, diet body. By methods recuperation maintenance aiming at harmony, including building up health to improve ability adaption body resistance external environment, one can...
Aimed at the problem of product modeling under Mass Customization, concepts characteristic matrix and row were proposed.The function-structure model based on network nodes was established by combination identification constraints mapping relationship nodes.Finally, collaborative translation mechanism used as an example to illustrate that method can simplify repeatability design rapidly customization.
Objective To analyze the risk factors of cortical micro-infarcts (CMIs) in patients with acute ischemic stroke and to evaluate diagnostic value 3.0 Tesla (T) magnetic resonance imaging (MRI) using double inversion recovery (DIR) sequence 3-dimensional fluid attenuated (3D-FLAIR) CMIs vivo. Methods One hundred ten consecutive within 7 d onset were chosen from August 2014 July 2015; these classified into group non-CMIs by results conventional T MRI, DIR-MRI 3D-FLAIR-MRI. Baseline...
Diabetes is the world’s third largest threat to people’s health. In China, incidence of diabetes on rise, cure rate low, patients with complications are more, and bring a heavy economic burden family society. Compared developed countries, China still has big gap in terms care, education management, even less long-term follow-up management results. Therefore, diabetic should not only stay intervention during hospitalization, but also extend outside hospital. Only by implementing whole-process...
Air pollution caused by bacteria and viruses has posed a serious threat to public health. Commercial air purifiers based on dense fibrous filters can remove particulate matter including airborne pathogens, but do not kill them efficiently. Here, we applied antibacterial photodynamic therapy filtration developed double-grafted fiber material. Tetracarboxyl substituted phthalocyanine zinc, photosensitizer, was grafted onto the polyester (PET) fiber, followed coating with chitosan surface of...