A5114929644- Tracheal and airway disorders
- Sirtuins and Resveratrol in Medicine
- Pancreatitis Pathology and Treatment
- Asthma and respiratory diseases
- Sepsis Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Synthesis and Reactions of Organic Compounds
- Proteoglycans and glycosaminoglycans research
- Bioactive Compounds and Antitumor Agents
- Cystic Fibrosis Research Advances
- Dysphagia Assessment and Management
- Cell Adhesion Molecules Research
- Blood Coagulation and Thrombosis Mechanisms
- Obstructive Sleep Apnea Research
- Venous Thromboembolism Diagnosis and Management
- Synthesis of Organic Compounds
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Metabolism, Diabetes, and Cancer
- Pancreatic and Hepatic Oncology Research
- Oral and Maxillofacial Pathology
- Diabetes Management and Research
- Neonatal Respiratory Health Research
- IL-33, ST2, and ILC Pathways
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
China Medical University
2012-2023
Abstract Backgrounds Stress hyperglycemia ratio (SHR) reflects the acute blood glucose change in response to illnesses or injuries, including pneumonia. We aimed investigate associations of SHR with systemic inflammation and clinical outcomes diabetic inpatients pneumonia on admission. Methods A multicenter retrospective study was conducted among admission via electronic medical records from 2013 2019 Ruijin Hospital, Shengjing China‐Japan Friendship Hospital. Results The included 1631...
Insulin resistance is one of important factors causing type 2 diabetes; therefore, regulating insulin sensitivity considered a beneficial therapeutic approach against diabetes. The present study aimed to determine the effects N1‑methylnicotinamide (MNAM) on (IR) in skeletal muscle from mouse model diabetes mellitus (T2DM), and investigate regulatory mechanisms sirtuin 1 (SIRT1)/peroxisome proliferator‑activated receptor γ coactivator‑1α (PGC‑1α) signaling pathway. C57BL/6 mice were fed...
Abstract Background Bronchiectasis is a highly heterogeneous chronic airway disease with marked geographic and ethnic variations. Most influential cohort studies to date have been performed in Europe USA, which serve as the examples for developing study China where there high burden of bronchiectasis. The Establishment Registry Research Collaboration (BE-China) designed to: (1) describe clinical characteristics natural history bronchiectasis identify differences between western countries...
Shikonin (SK), a naturally occurring naphthoquinone, exhibits antitumor activity. However, its precise mechanisms of action are unknown. In the present study, effects SK on NCI-H460 human lung cancer cells were investigated. It was found that reduced cell viability and induced apoptosis in cells. Additionally, inhibited extracellular signal-regulated kinase (ERK) activity, which indicates inhibition ERK pathway is probably one by apoptosis. The expression Cbl-b significantly increased...
Abstract Discoidin domain receptors 1 and 2 (DDR1 DDR2) are members of the receptor tyrosine kinases, which regulate fundamental cellular processes concerning proliferation, differentiation, adhesion, motility, apoptosis. The dysregulation these is linked to a number human diseases, including fibrotic disorders, atherosclerosis, cancer. However, there have been no studies that analyzed expression DDRs in ameloblastomas (ABs). In this study, we investigated level distribution both ABs...
Background Diffuse panbronchiolitis (DPB) is a progressive inflammatory pulmonary disease that predominately affects East Asians. Genetic susceptibility to DPB correlated with the human leukocyte antigens HLA-B54 in Japanese and HLA-A11 Koreans. However, no systematic genetic study of pathogenesis has been conducted Chinese population. The aim this was investigate possible association between HLA patients DPB. Methods A literature review both English language studies on patients, published...
A 60-year-old man with septicemia received an IV infusion of tigecycline (first 100 mg, then 50 mg every 12 hours). The patient developed abdominal distension, pain, and tenderness at left lower abdomen on the tenth day cumulative medication. Laboratory tests showed following values: white blood cell (WBC) 18.4×109/L, neutrophile granulocyte 0.90, serum amylase 432 U/L, lipase urinea 389 U/L. result CT effusion in pelvis, exudation around duodenum stomach. was diagnosed as acute pancreatitis...
Objective To explore the safety and efficacy of recombinant tissue-type plasminogen activator (rtPA) to do literature case review Methods The related data-bases were searched. The literatures about treatment for pregnant women with pulmonary embolism by rtPA was collected. patients′basic information, situation fibrinolytic therapy (including type, dosage, usage rtPA, outcomes therapy), occurrence ADR, pregnancy recorded. A descriptive statistical analysis above-mentioned results...