A5039327777- Particle Accelerators and Free-Electron Lasers
- Particle accelerators and beam dynamics
- Radiation Therapy and Dosimetry
- Particle Detector Development and Performance
- Gyrotron and Vacuum Electronics Research
- Radiation Detection and Scintillator Technologies
- Radiation Effects in Electronics
- Photonic Crystal and Fiber Optics
- Superconducting Materials and Applications
- Laser-Matter Interactions and Applications
- Advanced Radiotherapy Techniques
- Advanced Fiber Laser Technologies
- Laser Material Processing Techniques
- Microwave Engineering and Waveguides
- Optical Network Technologies
- Solid State Laser Technologies
- Laser and Thermal Forming Techniques
- Laser Design and Applications
- Neutrino Physics Research
- Electromagnetic Simulation and Numerical Methods
- Laser-Plasma Interactions and Diagnostics
- Optical Coherence Tomography Applications
- Semiconductor Lasers and Optical Devices
- Integrated Circuits and Semiconductor Failure Analysis
- Electron and X-Ray Spectroscopy Techniques
European Organization for Nuclear Research
2018-2025
Lawrence Berkeley National Laboratory
2021-2023
SLAC National Accelerator Laboratory
2022-2023
Linac Coherent Light Source
2023
University of Naples Federico II
2019-2022
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2021
Laboratoire d'Informatique, de Robotique et de Microélectronique de Montpellier
2021
University of Jyväskylä
2021
European Space Research and Technology Centre
2021
Vanderbilt University
2021
The R2E project at CERN has tested a few commercial SRAMs and custom-designed SRAM, whose data are complementary to various scientific publications. experimental include low- high-energy protons, heavy ions, thermal, intermediate- neutrons, electrons pions.
Abstract High dose-rate radiotherapy, known as FLASH, has been shown to increase the differential response between healthy and tumour tissue. Moreover, Very Energy Electrons (VHEEs) provide more favourable dose distributions than conventional radiotherapy electron photon beams. Plane-parallel ionisation chambers are recommended secondary standard systems for clinical reference dosimetry of electrons, therefore chamber these high energy dose-per-pulse beams must be well understood. Graphite...
Abstract Very high energy electron (VHEE) beams have been proposed as an alternative radiotherapy modality to megavoltage photons; they penetrate deeply without significant scattering in inhomogeneous tissue because of their relativistic inertia. However, the depth dose distribution a single, collimated VHEE beam is quasi-uniform, which can lead healthy being overexposed. This be largely overcome by focusing small spot. Here, we present experiments demonstrate means concentrating into...
Abstract This paper presents the first plasmid DNA irradiations carried out with Very High Energy Electrons (VHEE) over 100–200 MeV at CLEAR user facility CERN to determine Relative Biological Effectiveness (RBE) of VHEE. damage yields were measured in dry and aqueous environments that ~ 99% total breaks caused by indirect effects, consistent other published measurements for protons photons. Double-Strand Break (DSB) yield was used as biological endpoint RBE calculation, values found be...
Optical Beam-Loss Monitors (oBLMs) allow for cost-efficient and spatially continuous measurements of beam losses at accelerator facilities. A standard oBLM consists several tens metres optical fibre aligned parallel to a beamline, coupled photosensors either or both ends. Using the timing information from loss signals, positions can be reconstructed. This paper presents novel system recently deployed CERN Linear Electron Accelerator Research (CLEAR). Multiple methods extracting position...
The aim of this work is the dosimetric characterization a plane parallel ionization chamber under defined beam setups at CERN Linear Electron Accelerator for Research (CLEAR). A laser driven electron with energy 200 MeV two different field sizes approximately 3.5 mm FWHM and 7 were used pulse structures. Thereby dose-per-pulse range varied between 0.2 12 Gy per pulse. This represents conventional dose rate conditions up to ultra-high (UHDR) conditions. experiment was based on water phantom...
An 8-beam, diffractive coherent beam combiner is phase controlled by a learning algorithm trained while optical phases drift, using differential mapping technique. Combined output power stable to 0.4% with 95% of theoretical maximum efficiency, limited the element.
In this work, non-destructive virtual diagnostics are applied to retrieve the electron beam time of arrival and energy in a relativistic ultrafast diffraction (UED) beamline using independently-measured machine parameters. This technique has potential improve temporal resolution pump probe UED scans. Fluctuations have multiple components, including shot-to-shot jitter long-term drift which can be separately addressed by closed loop feedback systems. A linear-regression-based model is used...
Over the past two decades, serial X-ray crystallography has enabled structure determination of a wide range proteins. With advent free-electron lasers (XFELs), ever-smaller crystals have yielded high-resolution diffraction and determination. A crucial need to continue advancement is efficient delivery fragile micrometre-sized beam intersection. This paper presents an improved design all-polymer microfluidic `chip' for room-temperature fixed-target that can be tailored broadly meet needs...
We demonstrate ultra-broadband spectral combining of ultrashort pulses from Yb-doped fiber amplifiers, with coherently spectrally synthesized pulse shaping, to achieve tens-of-fs pulses. This method can fully compensate for gain narrowing and high order dispersion over broad bandwidth. produce 42fs by synthesizing three chirped-pulse amplifiers two programmable shapers across an 80nm overall To the best our knowledge, this is shortest duration achieved a combined system at one-micron...
We present the observation and detailed investigation of coherent Cherenkov diffraction radiation (CChDR) in terms spectral-angular characteristics. Electromagnetic simulations have been performed to optimize design a prismatic dielectric radiator performance detection system with aim providing longitudinal beam diagnostics. Successful experimental validations organized on CLEAR CLARA facilities based at CERN Daresbury laboratory respectively. With ps sub-ps long electron bunches, emitted...
Abstract Recent results from pre-clinical studies investigating the so-called FLASH effect suggest that ultrahigh pulse dose rates (UHPDR) of this modality reduces normal tissue damage whilst preserving tumour response, when compared with conventional radiotherapy (RT). FLASH-RT is characterized by average dozens Gy/s instead only a few Gy/min. For some studies, exceeding hundreds have been used for response. Moreover, depending on source radiation, pulsed beams can be low repetition rate...
ou non, émanant des établissements d'enseignement et de recherche français étrangers, laboratoires publics privés.
The CERN Linear Electron Accelerator for Research (CLEAR) has now finished its second year of operation, providing a testbed new accelerator technologies and versatile radiation source. Hosting varied experimental program, this beamline provides flexible test facility users both internal external to CERN, as well being an excellent physics training ground. energy can be between 60 220 MeV, bunch length 1 4 ps, charge in the range 10 pC 2 nC, number bunches 200, at repetition rate 0.8 Hz....
We analyze a new kind of machine learning algorithm designed to feedback stabilize coherently combined lasers. This learns differential, rather than absolute, values action in phase space, order facilitate on initially unstable systems. Experiments have shown that this approach can control small-scale spatial beam combination with high stability. In paper we the algorithm's performance and limitations depth, showing it continuously learn during operation track changes. Using simulation,...
Abstract A method to monitor the length of a particle bunch, based on combination Radio Frequency Deflector (RFD) with magnetic focusing elements, is presented. With respect state-of-the-art bunch measurement, additional element allows measure also correlations between longitudinal and transverse planes in terms both position divergence. Furthermore, quadrupole-based increases input dynamic range measurement system (i.e. for larger beam Twiss parameters at entrance RFD). Thus, resolution...
We study the radiation environment near terahertz (THz) dump of CERN Linear Electron Accelerator for Research (CLEAR) electron accelerator at CERN, using FLUktuierende KAskade in German (FLUKA) simulations and single-event upset (SEU) measurements taken with 32-Mbit Integrated Silicon Solution Inc. (ISSI) static random access memories (SRAMs). The main focus is on characterization neutron field to evaluate its suitability tests electronics comparison other irradiation facilities. Neutrons...
In high-brightness electron linear accelerators (LINACs), the particle bunch length is measured by a radio frequency deflector (RFD). The deflected vertically toward screen and its can be obtained using vertical spot size measurements after proper calibration, e.g., measuring centroid while varying deflecting voltage phase. energy parameters of (the chirp spread) correlation between positions, divergences, energies contribute to dimension at position RFD so far were considered as source...
Rotating-coil measurement systems are widely used to measure the multipolar fields of particle accelerator magnets. This paper presents a rotating-coil system that aims at providing complete data set for characterization quadrupole magnets with small bore diameters (26 mm). The PCB magnetometer design represents challenging goal this type transducer. It is characterized by an aspect ratio 30% higher than state art, imposed reduced dimension external radius rotating shaft and necessity...
The paper describes an experimental analysis for the definition of design parameters High-order Modes couplers, used to damp electromagnetic resonances in equipment. consists characterization RF equipment alone and with insertion High-Order (HOM) couplers different lengths diameters. has been applied a test at European Organization Nuclear Research (CERN), where significant reduction resonance obtained certain configurations parameters. In paper, full method is explained: theoretical idea,...