A5018524388- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Intensive Care Unit Cognitive Disorders
- Stroke Rehabilitation and Recovery
- Telemedicine and Telehealth Implementation
- Pain Mechanisms and Treatments
- EEG and Brain-Computer Interfaces
- Cerebral Palsy and Movement Disorders
- Musculoskeletal pain and rehabilitation
- Neuroinflammation and Neurodegeneration Mechanisms
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Spinal Cord Injury Research
- Pain Management and Treatment
- Cancer-related cognitive impairment studies
- Prosthetics and Rehabilitation Robotics
- COVID-19 and healthcare impacts
- Psychosomatic Disorders and Their Treatments
- Technology Use by Older Adults
- Epilepsy research and treatment
- Muscle activation and electromyography studies
- Hemodynamic Monitoring and Therapy
- Cardiovascular Syncope and Autonomic Disorders
- Assistive Technology in Communication and Mobility
- Takotsubo Cardiomyopathy and Associated Phenomena
- Mobile Health and mHealth Applications
Stony Brook School
2024
Stony Brook University
2024
Icahn School of Medicine at Mount Sinai
2020-2024
Abstract Post-acute infection syndromes may develop after acute viral disease 1 . Infection with SARS-CoV-2 can result in the development of a post-acute syndrome known as long COVID. Individuals COVID frequently report unremitting fatigue, post-exertional malaise, and variety cognitive autonomic dysfunctions 2–4 However, biological processes that are associated persistence these symptoms unclear. Here 275 individuals or without were enrolled cross-sectional study included multidimensional...
COVID survivors frequently experience lingering neurological symptoms that resemble cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial reactivity and consequent neural dysregulation is central. Here, we explored the neurobiological effects of respiratory SARS-CoV-2 infection found white-matter-selective in mice humans. Following mild mice, persistently impaired hippocampal neurogenesis, decreased oligodendrocytes, myelin loss were evident together with...
SARS-CoV-2 infection can result in the development of a constellation persistent sequelae following acute disease called post-acute COVID-19 (PASC) or Long COVID 1-3 . Individuals diagnosed with frequently report unremitting fatigue, post-exertional malaise, and variety cognitive autonomic dysfunctions ; however, basic biological mechanisms responsible for these debilitating symptoms are unclear. Here, 215 individuals were included an exploratory, cross-sectional study to perform...
This report describes persistent symptoms associated with post-acute COVID-19 syndrome (PACS) and the impact of these on physical function, cognitive health-related quality life, participation.This study used a cross-sectional observational design. Patients attending Mount Sinai's clinic completed surveys containing patient-reported outcomes.A total 156 patients survey, at median (range) time 351 days (82-457 days) after infection. All were prevaccination. The most common reported fatigue (n...
Survivors of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection frequently experience lingering neurological symptoms, including impairment in attention, concentration, speed information processing and memory. This long-COVID cognitive syndrome shares many features with the cancer therapy-related (CRCI). Neuroinflammation, particularly microglial reactivity consequent dysregulation hippocampal neurogenesis oligodendrocyte lineage cells, is central to CRCI. We hypothesized...
Background: Coronavirus disease 2019 (COVID-19) poses a global public health emergency, overwhelming systems worldwide and forcing rapid adoption of telemedicine strategies.
Abstract Introduction One of the noted features COVID-19 is spectrum expressivity in symptoms among those with disease, ranging from no or mild that may last a small number days, to severe and/or longer lasting symptoms. It emerging many patients have long symptoms, several months after initial infection COVID-19. The aim this research was characterize post-acute syndrome (PACS). Methods This retrospective cross-sectional observational study. Participants were recovering infection, enrolled...
Introduction: Telehealth was frequently used in the provision of care and remote patient monitoring (RPM) during COVID-19 pandemic. The Precision Recovery Program (PRP) remotely monitored supported patients with their home environment. Materials Methods: This a single-center retrospective cohort study reviewing data acquired from PRP clinical initiative. Results: Of 679 enrolled PRP, 156 were screened by clinician following deterioration symptoms vital signs on total 240 occasions, included...
Abstract Introduction: Neuropathic pain (NP) poses significant challenges for individuals with spinal cord injury (SCI), often inadequately managed by current interventions. Immersive virtual reality (IVR) has emerged as a promising approach modulation, yet robust evidence is lacking. Objectives: This pilot study investigated the analgesic effects of different IVR environments (scenic, somatic) compared control environment, and explored psychomotor properties influencing attenuation....
Emerging literature suggests that virtual reality (VR) may be a viable therapy for neuropathic pain (NP). This pilot study aimed to investigate the immediate effect of VR in reducing NP people with spinal cord injury (SCI). Eight individuals chronic after SCI were recruited and underwent consecutive exposure scenery somatic environments (VE). The numeric rating scale (NRS) was used assess before each VE. Immersive Tendencies Questionnaire (ITQ) Presence (UQO-PQ) interaction between reported...
Abstract Post-acute COVID-19 syndrome (PACS) is a collection of persistent and debilitating symptoms lasting weeks to months after acute infection, with fatigue most commonly reported. There controversy surrounding the role exercise programs for this condition, due concerns over potential worsen fatigue. We developed novel physical therapy program known as Autonomic Conditioning Therapy (ACT) PACS, report on preliminary patient-reported outcome (PRO) data from individuals who completed ACT...
Despite the prevalence of dysautonomia in people with Long COVID, it is currently unknown whether COVID routinely accompanied by structural or functional cardiac alterations. In this retrospective observational study, presence echocardiographic abnormalities was assessed. Left ventricular (LV) chamber sizes were correlated to diagnostic categories and symptoms via standardized patient-reported outcome (PRO) questionnaires. A total 203 individuals without pre-existing disease available...
Strict blood pressure (BP) control is a universally accepted therapeutic intervention in the prevention of secondary stroke, yet this remains difficult when patients return home postinjury. This study aimed to investigate application remote patient monitoring (RPM) BP after or who were at immediate risk and subsequent outcomes relating triage escalation care.This was single-center proof-of-concept study. Participants aged 18 years older with diagnosis stroke stroke. Patients enrolled into...
Abstract Neuropathic Pain (NP) affects 10% of the general population, decreasing quality life for millions Americans and contributing to higher physical mental health care costs. The most widely used treatments NP involve medications that show limitations in efficacy burdensome side effects. This randomized controlled trial explored a wearable Audio-Visual Stimulation neuromodulation device (Sana) as novel intervention chronic 64 participants. Outcomes were assessed at baseline, after...
Introduction: To evaluate if the offering of Fitbit technology led to changes in cardiovascular health metrics a cohort older adults. Methods: A retrospective study was developed two community-embedded monitoring sites, located aggregate housing communities for adults Westchester County, NY. Participants included (55 years or older) enrolled Telehealth Intervention Programs Seniors (TIPS) initiative, remote patient initiative. Weekly blood pressure, heart rate, weight, and oxygenation were...
BACKGROUND: Advanced technologies are increasingly used to address impaired mobility after neurological insults, with growing evidence of their benefits for various populations. However, certain robotic devices have not been extensively investigated in specific conditions, limiting knowledge about optimal application healthcare. OBJECTIVE: To compare effectiveness conventional gait training exoskeleton-assisted walking non-traumatic brain injury during early stage rehabilitation. METHODS:...