- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- MRI in cancer diagnosis
- Photoacoustic and Ultrasonic Imaging
- Cerebral Venous Sinus Thrombosis
- Lanthanide and Transition Metal Complexes
- Meningioma and schwannoma management
- Spine and Intervertebral Disc Pathology
- Cardiovascular Disease and Adiposity
- Ophthalmology and Eye Disorders
- Prostate Cancer Treatment and Research
- Medical Imaging and Analysis
- Atomic and Subatomic Physics Research
- Radiology practices and education
- Adipose Tissue and Metabolism
- Glaucoma and retinal disorders
- Radiation Therapy and Dosimetry
- Neurofibromatosis and Schwannoma Cases
- Dental Radiography and Imaging
University of Zurich
2019-2025
University of Fribourg
2025
Maastricht University
2021-2024
University Hospital of Zurich
2019-2024
Kantonsspital Winterthur
2017-2024
Kantonsspital Baden
2023-2024
J.P. Morgan
2024
Ferioli & Gianotti (Italy)
2024
Bayer (United States)
2023
University of Lucerne
2023
The aim of this study was to evaluate the feasibility and quality ultra-high-resolution coronary computed tomography angiography (CCTA) with dual-source photon-counting detector CT (PCD-CT) in patients a high calcium load, including an analysis optimal reconstruction kernel matrix size.In institutional review board-approved study, 20 (6 women; mean age, 79 ± 10 years; body mass index, 25.6 4.3 kg/m 2 ) undergoing PCD-CCTA mode were included. Ultra-high-resolution CCTA acquired...
The aims of this study were to determine the objective and subjective image quality high-pitch computed tomography (CT) angiography aorta in clinical dual-source photon-counting detector CT (PCD-CT) compare conventional energy-integrating (EID-CT) same patients at equal radiation dose.Patients with prior thoracoabdominal acquired on third-generation EID-CT mode automatic tube voltage selection (ATVS, reference 100 kV) included. Follow-up imaging was performed a first-generation, PCD-CT...
Background An iterative reconstruction (IR) algorithm was introduced for clinical photon-counting detector (PCD) CT. Purpose To investigate the image quality and optimal strength level of a quantum IR (QIR; Siemens Healthcare) virtual monoenergetic images polychromatic (T3D) in phantom patients undergoing portal venous abdominal PCD Materials Methods In this retrospective study, noise power spectrum (NPS) measured water-filled phantom. Consecutive oncologic who underwent CT between March...
The aim of this study was to evaluate the feasibility and accuracy cardiac late enhancement (LE) scanning for extracellular volume (ECV) quantification with dual-source photon-counting detector computed tomography (PCD-CT).In institutional review board-approved study, 30 patients (mean age, 79 years; 12 women; mean body mass index, 28 kg/m2) severe aortic stenosis undergoing PCD-CT as part their preprocedural workup transcatheter valve replacement were included. scan protocol consisted a...
The aim of this study was to characterize image quality and determine the optimal strength levels a novel iterative reconstruction algorithm (quantum reconstruction, QIR) for low-dose, ultra-high-resolution (UHR) photon-counting detector CT (PCD-CT) lung. Images were acquired on clinical dual-source PCD-CT in UHR mode reconstructed with sharp lung kernel at different QIR (QIR-1 QIR-4) without (QIR-off). Noise power spectrum (NPS) target transfer function (TTF) analyzed cylindrical phantom....
The aim of this study was to determine the potential photon-counting detector computed tomography (PCD-CT) for radiation dose reduction compared with conventional energy-integrated CT (EID-CT) in assessment interstitial lung disease (ILD) systemic sclerosis (SSc) patients.In retrospective study, SSc patients receiving a follow-up noncontrast chest examination on PCD-CT were included between May 2021 and December 2021. Baseline scans generated dual-source EID-CT by selecting tube current-time...
Background Accurate CT attenuation and diagnostic quality of virtual noncontrast (VNC) images acquired with photon-counting detector (PCD) are needed to replace true (TNC) scans. Purpose To assess the errors image VNC from abdominal PCD compared TNC images. Materials Methods In this retrospective study, consecutive adult patients who underwent a triphasic examination July 2021 October were included. reconstructed arterial portal venous phase CT. The absolute error was measured in multiple...
Objectives: To assess the impact of low kilo-electronvolt (keV) virtual monoenergetic image (VMI) energies and iterative reconstruction on quality clinical photon-counting detector coronary CT angiography (CCTA). Methods: CCTA with PCD-CT (prospective ECG-triggering, 120 kVp, automatic tube current modulation) was performed in a high-end cardiovascular phantom dynamic flow, pulsatile heart motion, including different calcified plaques various stenosis grades 10 consecutive patients. VMI at...
Purpose To assess the accuracy of aortic valve calcium (AVC), mitral annular (MAC), and coronary artery (CAC) quantification risk stratification using virtual noncontrast (VNC) images from late enhancement photon-counting detector CT as compared with true images. Materials Methods This retrospective, institutional review board–approved study evaluated patients undergoing between January September 2022. VNC were reconstructed cardiac scans at 60, 70, 80, 90 keV quantum iterative...
Acceleration of MR sequences beyond current parallel imaging techniques is possible with the Compressed SENSE technique that has recently become available for 1.5 and 3 Tesla scanners, nearly all image contrasts 2D 3D sequences. The impact this on examination timing parameters protocols in a clinical setting was investigated retrospective study.A numerical analysis (scan time, exam procedure interscan delay changeover nonscan time) based 6 different body regions (brain, knee, lumbar spine,...
The aim of this study was to assess the accuracy virtual noncontrast (VNC) images liver in a phantom and patients using dual-source photon-counting detector computed tomography (PCD-CT).An anthropomorphic abdominal with insert containing parenchyma (1.4 mgI/mL) 19 lesions (iodine content 0-5 imaged on clinical PCD-CT (tube voltage 120 kV) dual-energy mode energy-integrating (EID) CT combinations, 80/Sn150 kV, 90/Sn150 100/Sn150 kV). Rings fat-equivalent material were added emulate 3 sizes...
Abstract Objectives To compare the value of zero echo time (ZTE) and gradient “black bone” (BB) MRI sequences for bone assessment sacroiliac joint (SI) using computed tomography (CT) as reference standard. Materials methods Between May 2019 January 2021, 79 patients prospectively underwent clinically indicated 3-T including ZTE BB imaging. Additionally, all a CT scan covering SI joints within 12 months examination. Two blinded readers performed by grading each side qualitatively in terms...
Purpose The aim of this study was to assess the effect temporal resolution on subjective and objective image quality coronary computed tomography angiography (CCTA) in ultra-high-resolution (UHR) mode with dual-source photon-counting detector (PCD) CT. Materials Methods This retrospective, institutional review board–approved evaluated 30 patients (9 women; mean age, 80 ± 10 years) undergoing UHR CCTA a clinical PCD-CT scanner. Images were acquired tube voltage 120 kV using collimation × 0.2...
Abstract We sought to evaluate the utility of radiomics for Amide Proton Transfer weighted (APTw) imaging by assessing its value in differentiating brain metastases from high- and low grade glial tumors. retrospectively identified 48 treatment-naïve patients (10 WHO 2, 1 3, 10 4 primary tumors 27 metastases) with either or who had undergone APTw MR imaging. After image analysis feature extraction post-processing, machine learning algorithms (multilayer perceptron algorithm; random forest...
Epicardial Adipose Tissue Attenuation and Fat Index: Phantom Study In Vivo Measurements With Photon-Counting Detector CTVictor Mergen, MD1, Emanuel Ried, Thomas Allmendinger, PhD2, Sartoretti, BMed1, Kai Higashigaito, Robert Manka, MD1,3, Andre Euler, Hatem Alkadhi, MD, MPH1 Matthias Eberhard, MD1Audio Available | Share
To evaluate the performance of virtual non-contrast images (VNC) compared to true (TNC) in photon-counting detector computed tomography (PCD-CT) for evaluation lung parenchyma and emphysema quantification.
Abstract To investigate the applicability and performance of automated machine learning (AutoML) for potential applications in diagnostic neuroradiology. In medical sector, there is a rapidly growing demand methods, but only limited number corresponding experts. The comparatively simple handling AutoML should enable even non-experts to develop adequate models with manageable effort. We aim feasibility as well advantages disadvantages developing compared conventional models. discuss results...
To assess the accuracy of low-dose dual-energy computed tomography (DECT) to differentiate uric acid from non-uric kidney stones in two generations dual-source DECT with stone composition analysis as reference standard.
Abstract Background Despite the increasing interest in abbreviated protocols, we adopted an extended protocol for all prostate MRIs. In this study, assessed benefits of MRI protocol, measured by number and clinical importance additional findings (AFs) their impact on patient management. Methods a single-center retrospectively included 1282 patients undergoing between 01.10.2018 30.04.2022. Additional were defined as any pathology not located or seminal vesicles. These classified related...
Objective The aim of the study is to compare image quality and homogeneity vessel enhancement in high-pitch CT-angiography aorta (CTA) prior transcatheter aortic valve implantation between bolus tracking with a fixed trigger delay patient-specific delay. Materials Methods In this retrospective study, consecutive patients who received CTA January 2023 June 2024 were included. Patients imaged using either (Group A; 15 seconds) or B; FAST Bolus; Siemens Healthineers AG). same contrast injection...