A5049370538- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac Imaging and Diagnostics
- Head and Neck Surgical Oncology
- Systemic Sclerosis and Related Diseases
- Neurofibromatosis and Schwannoma Cases
- Meningioma and schwannoma management
- Lung Cancer Treatments and Mutations
- Aortic aneurysm repair treatments
- Infrared Thermography in Medicine
- Healthcare Systems and Practices
- Nosocomial Infections in ICU
- Thyroid Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Head and Neck Cancer Studies
- Oral Health Pathology and Treatment
- COVID-19 Clinical Research Studies
- Pelvic and Acetabular Injuries
- Thermal Regulation in Medicine
- Pediatric health and respiratory diseases
University Hospital of Zurich
2021-2025
University of Zurich
2022-2024
Anna Needs Neuroblastoma Answers
2024
Kantonsspital Baden
2024
Prevention Institute
2023
University of Lausanne
2022
Society of Interventional Radiology
2021-2022
LMU Klinikum
2017
Ludwig-Maximilians-Universität München
2017
The aim of this study was to evaluate the feasibility and accuracy cardiac late enhancement (LE) scanning for extracellular volume (ECV) quantification with dual-source photon-counting detector computed tomography (PCD-CT).In institutional review board-approved study, 30 patients (mean age, 79 years; 12 women; mean body mass index, 28 kg/m2) severe aortic stenosis undergoing PCD-CT as part their preprocedural workup transcatheter valve replacement were included. scan protocol consisted a...
To develop and evaluate a low-volume contrast media protocol for thoracoabdominal CT angiography (CTA) with photon-counting detector (PCD) CT.This prospective study included consecutive participants (April-September 2021) who underwent CTA PCD of the aorta previous energy-integrating (EID) at equal radiation doses. In CT, virtual monoenergetic images (VMI) were reconstructed in 5-keV intervals from 40 to 60 keV. Attenuation aorta, image noise, contrast-to-noise ratio (CNR) measured,...
68Ga-DOTATATE PET/CT enables detection of meningioma tissue based on somatostatin receptor 2 expression. Transosseous extension intracranial meningiomas is known to be an important risk factor for tumor recurrence and patient mortality. We analyzed the diagnostic performance contrast-enhanced MRI (CE-MRI) osseous infiltration using qualitative quantitative imaging parameters. Methods: In this institutional review board-approved retrospective study, subjects were selected from 327 consecutive...
Objective The aim of this study was to evaluate the image quality (IQ) and performance an artificial intelligence (AI)-based computer-aided detection (CAD) system in photon-counting detector computed tomography (PCD-CT) for pulmonary nodule evaluation at different low-dose levels. Materials Methods An anthropomorphic chest-phantom containing 14 nodules sizes (range, 3–12 mm) imaged on a PCD-CT conventional energy-integrating CT (EID-CT). Scans were performed with each 3 vendor-specific...
The aim of this study was to characterize image quality and determine the optimal strength levels a novel iterative reconstruction algorithm (quantum reconstruction, QIR) for low-dose, ultra-high-resolution (UHR) photon-counting detector CT (PCD-CT) lung. Images were acquired on clinical dual-source PCD-CT in UHR mode reconstructed with sharp lung kernel at different QIR (QIR-1 QIR-4) without (QIR-off). Noise power spectrum (NPS) target transfer function (TTF) analyzed cylindrical phantom....
The aim of this study was to determine the potential photon-counting detector computed tomography (PCD-CT) for radiation dose reduction compared with conventional energy-integrated CT (EID-CT) in assessment interstitial lung disease (ILD) systemic sclerosis (SSc) patients.In retrospective study, SSc patients receiving a follow-up noncontrast chest examination on PCD-CT were included between May 2021 and December 2021. Baseline scans generated dual-source EID-CT by selecting tube current-time...
Background Accurate CT attenuation and diagnostic quality of virtual noncontrast (VNC) images acquired with photon-counting detector (PCD) are needed to replace true (TNC) scans. Purpose To assess the errors image VNC from abdominal PCD compared TNC images. Materials Methods In this retrospective study, consecutive adult patients who underwent a triphasic examination July 2021 October were included. reconstructed arterial portal venous phase CT. The absolute error was measured in multiple...
To evaluate the performance of virtual non-contrast images (VNC) compared to true (TNC) in photon-counting detector computed tomography (PCD-CT) for evaluation lung parenchyma and emphysema quantification.
Purpose The aim of this study was to evaluate the impact contrast enhancement and different virtual monoenergetic image energies on automatized emphysema quantification with photon-counting detector computed tomography (PCD-CT). Material Methods Sixty patients who underwent contrast-enhanced chest CT a first-generation, clinical dual-source PCD-CT were retrospectively included. Scans performed in multienergy (QuantumPlus) mode at 120 kV weight-adjusted intravenous agent. Virtual noncontrast...
The aim of the study was to evaluate effect photon-counting detector (PCD-)CT dose reduction x-ray equivalent levels on nodule detection, diameter, volume, and density compared a low-dose reference standard using semiautomated manual methods. Between February July 2023, 101 prospectively enrolled participants underwent noncontrast same-study low- chest x-ray-dose CT scans PCD-CT. Patients who were not referred for lung cancer screening or follow-up, as well those with nodules smaller than 5...
The purpose of this study was to evaluate the impact virtual monoenergetic image (VMI) energies and iodine maps on diagnosis pleural empyema with photon counting detector computed tomography (PCD-CT).In IRB-approved retrospective study, consecutive patients non-infectious effusion or histopathology-proven were included. PCD-CT examinations performed a dual-source in multi-energy (QuantumPlus) mode at 120 kV weight-adjusted intravenous contrast-agent. VMIs from 40-70 keV obtained 10 intervals...
Zusammenfassung Klinisches/Methodisches Problem Die Identifizierung von raucherassoziierten Lungenerkrankungen (SRILD) bei Rauchern ist herausfordernd, da die klinischen Manifestationen unspezifisch sein können und es eine Vielzahl SRILD gibt, welche nicht nur ineinander übergehen, sondern auch überlappend vorkommen können. Radiologische Standardverfahren Bei der Diagnose ermöglichen bildgebende Verfahren wie hochauflösende CT (HRCT) charakteristischer Merkmale dienen daher als wichtiges...
Radiation dose should be as low reasonably achievable. With the invention of photon-counting detector computed tomography (PCD-CT), radiation may considerably reduced.
The aim of this study was to evaluate the impact contrast enhancement and different virtual monoenergetic image energies on automatized emphysema quantification with photon-counting detector computed tomography (PCD-CT).Sixty patients who underwent contrast-enhanced chest CT a first-generation, clinical dual-source PCD-CT were retrospectively included. Scans performed in multienergy (QuantumPlus) mode at 120 kV weight-adjusted intravenous agent. Virtual noncontrast (VNC) images as well...
Purpose To compare image quality, diagnostic performance, and conspicuity between single-energy multi-energy images for endoleak detection at CT angiography (CTA) after endovascular aortic repair (EVAR). Materials Methods In this single-center prospective randomized controlled trial, individuals undergoing CTA EVAR August 2020 May 2022 were allocated to imaging using either low-kilovolt (SEI; 80 kV, group A) or low-kiloelectron volt virtual monoenergetic (VMI) 40 50 keV from (80/Sn150 B)....
Objectives The aim of this study was to evaluate the feasibility and efficacy visual scoring, low-attenuation volume (LAV), deep learning methods for estimating emphysema extent in x-ray dose photon-counting detector computed tomography (PCD-CT), aiming explore future reduction potentials. Methods One hundred one prospectively enrolled patients underwent noncontrast low- chest CT scans same using PCD-CT. Overall image quality, sharpness, noise, as well pattern (no, trace, mild, moderate,...
To assess image quality and detectability of interstitial lung changes using multiple radiation doses from the same chest CT scan patients with suspected disease (ILD).Retrospective study consecutive adult ILD receiving unenhanced as single-energy dual-source acquisition at 100 kVp (Dual-split mode). 67% 33% overall tube current time product were assigned to A B, respectively. 100%-dose was 2.34 ± 0.97 mGy. Five different (100%, 67%, 45%, 39%, 33%) reconstructed this single linear-blending...
This pilot study conducted in Switzerland aims to assess the implementation, execution, and performance of low-dose CT lung cancer screening (LDCT-LCS). With being leading cause cancer-related deaths Switzerland, seeks explore potential impact on reducing mortality rates. However, initiating a program poses challenges depends country-specific factors. prospective study, initiated October 2018, enrolled participants meeting National Lung Cancer Study criteria or risk above 1.5% according...
BACKGROUND: Lung cancer is the leading cause of cancer-related deaths in Switzerland. Despite this, there no lung screening program country. In United States, low-dose computed tomography (LDCT) partially established and endorsed by guidelines. Moreover, evidence growing that reduces mortality this was recently shown a large European randomized controlled trial. Implementation program, however, challenging depends on many country-specific factors. The goal article to outline potential Swiss...
We evaluated the prognostic value of Sarcopenia, low precardial adipose-tissue (PAT), and high tumor-volume in outcome surgically-treated pleural mesothelioma (PM).
To assess the impact of lung cancer screening protocol recommended by European Society Thoracic Imaging (ESTI) on nodule diameter, volume, and density throughout different computed tomography (CT) scanners.An anthropomorphic chest phantom containing fourteen different-sized (range 3-12 mm) CT-attenuated (100 HU, -630 HU -800 termed as solid, GG1 GG2) pulmonary nodules was imaged five CT scanners with institute-specific standard protocols (PS) ESTI (ESTI protocol, PE). Images were...
Abstract Objective This study assessed the potential of ultra-high resolution (UHR) and a 1024-matrix in photon-counting-detector CT (PCD-CT) for evaluating interstitial lung disease (ILD) systemic sclerosis (SSc) patients. Methods Sixty-six SSc patients who underwent ILD-CT screening on first-generation PCD-CT were retrospectively included. Scans performed UHR mode at 100 kVp with two different matrix sizes (512×512 1024x1024) reconstructed slice thicknesses 1.5 0.2 mm. Image noise,...