A5100617803- Photonic and Optical Devices
- Covalent Organic Framework Applications
- RNA Research and Splicing
- Mechanical and Optical Resonators
- Iron Metabolism and Disorders
- Advanced Fiber Laser Technologies
- Advanced Photocatalysis Techniques
- Photonic Crystals and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Hemoglobinopathies and Related Disorders
- Ion channel regulation and function
- Plant biochemistry and biosynthesis
- Nuclear Structure and Function
- Calcium signaling and nucleotide metabolism
- Cancer Treatment and Pharmacology
- Advanced Fiber Optic Sensors
- Cellular transport and secretion
- Enzyme Catalysis and Immobilization
- Nuclear Receptors and Signaling
- Photoreceptor and optogenetics research
- Plasmonic and Surface Plasmon Research
- Hereditary Neurological Disorders
- Catalytic Processes in Materials Science
- Trace Elements in Health
- Birth, Development, and Health
Beijing Normal University
2025
Anhui University of Science and Technology
2025
Southwest University of Science and Technology
2024-2025
Northwestern Polytechnical University
2025
Dana-Farber Cancer Institute
2017-2024
Washington University in St. Louis
2018-2024
Harvard University
2015-2024
Nanjing University of Posts and Telecommunications
2022-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2024
Central South University
2024
Wnt signaling plays critical roles during synaptic development and plasticity. However, the mechanisms by which Wnts are released travel to target cells unresolved. During development, secretion of Drosophila Wnt1, Wingless, requires function Evenness Interrupted (Evi)/Wls, a Wingless-binding protein that is secreted along with Wingless at neuromuscular junction. Given Evi transmembrane protein, these studies suggested presence novel vesicular mechanism trans-synaptic communication,...
Optical sensors, crucial in diverse fields like gravitational wave detection, biomedical imaging, and structural health monitoring, rely on optical phase to convey valuable information. Enhancing sensitivity is important for detecting weak signals. Exceptional points (EPs), identified non-Hermitian systems, offer great potential advanced given their marked response perturbations. However, strict physical requirements operating a sensor at EPs limit broader applications. Here, we introduce an...
Abstract Enzymatic stereoselectivity has typically been unrivalled by most chemical catalysts, especially in the conversion of small substrates. According to ‘lock-and-key theory’ 1,2 , enzymes have confined active sites accommodate their specific reacting substrates, a feature that is absent from catalysts. An interesting case this context formation cyanohydrins ketones and HCN, as reaction can be catalysed various classes including biological, inorganic organic ones 3–7 . We now report...
Cancer patients frequently develop chemotherapy-induced peripheral neuropathy (CIPN), a painful and long-lasting disorder with profound somatosensory deficits. There are no effective therapies to prevent or treat this disorder. Pathologically, CIPN is characterized by “dying-back” axonopathy that begins at intra-epidermal nerve terminals of sensory neurons progresses in retrograde fashion. Calcium dysregulation constitutes critical event CIPN, but it not known how chemotherapies such as...
Abstract The emerging concept of aerogel composite phase change materials (PCMs) represents a promising approach for thermal energy storage and utilization. However, the aerogels currently reported usually lack essential properties, thereby constraining their potential functional design advanced applications. Herein, multifunctional with characteristics thermoregulation performance are prepared by chemically crosslinking unidirectional freezing to make functionalized mineral‐based PCMs as...
The Internet of Things (IoT)1,2 employs a large number spatially distributed wireless sensors to monitor physical environments, e.g., temperature, humidity, and air pressure, has many applications, including environmental monitoring3, health care monitoring4, smart cities5, precision agriculture. A sensor can collect, analyze, transmit measurements its environment1,2. Currently, used in the IoT are predominately based on electronic devices that may suffer from electromagnetic interference...
Complex neural circuitry requires stable connections formed by lengthy axons. To maintain these functional circuits, fast transport delivers RNAs to distal axons where they undergo local translation. However, the mechanism that enables long-distance of RNA granules is not yet understood. Here, we demonstrate a complex containing and RNA-binding protein (RBP) SFPQ interacts selectively with tetrameric kinesin adaptor KLC1 motor KIF5A. We show binding KIF5A/KLC1 required for axon survival...
Abstract Optical whispering-gallery-mode microsensors are a promising platform for many applications, such as biomedical monitoring, magnetic sensing, and vibration detection. However, like other micro/nanosensors, they cannot simultaneously have two critical properties – ultrahigh sensitivity large detection area, which desired most sensing applications. Here, we report novel scanning microprobe optimized both features demonstrate enhanced Raman spectroscopy, providing high-specificity...
Dragon’s blood (DB) is a traditional Chinese medicine (TCM) with hemostatic effects and antibacterial properties. However, it still challenging to use for rapid hemostasis because of its insolubility. In this study, different amounts DB were loaded on mesoporous silica nanoparticles (MSNs) prepare series DB-MSN composites (5DB-MSN, 10DB-MSN, 20DB-MSN). could quickly release activate the intrinsic coagulation cascade simultaneously by MSN. Hemostasis tests demonstrated that showed superior...
Optical cavities that are capable for detecting single nanoparticles could lead to great progress in early stage disease diagnostics and the study of biological interactions on single-molecule level. In particular, photonic crystal (PhC) excellent platforms label-free single-nanoparticle detection, owing their high quality (Q) factors wavelength-scale modal volumes. Here, we demonstrate design fabrication a high-Q (>104) slot-mode PhC nanobeam cavity, which is able strongly confine...
In the medical industry, minimizing biofouling is of utmost importance as it helps to reduce bacterial adhesion and prevent cross-infection. this study, cyclized/knotted polydivinylbenzene (PDVB), a polymer with distinctive structural features, proposed for first time be utilized in preparation antibacterial coatings. Firstly, (PDVB) synthesized via deactivation-enhanced atom transfer radical polymerization (DE-ATRP). Subsequently, processed into coatings by employing "grafting to" method....
Abstract Amorphous MOFs have attracted more attentions due to their excellent adsorption performance. However, the transformation of crystalline MOF into amorphous often requires harsh conditions, and simple scalable amorphization strategies are still lacking. In this work, via a solvent‐assisted evaporation strategy is synthesized. The results show that gf BNU‐1(Zn) BNU‐1(Cd) glass foams with short‐range ordered but long‐range disordered atomic structure foam‐like multistage pore display...