- Foot and Ankle Surgery
- Food Allergy and Anaphylaxis Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Lower Extremity Biomechanics and Pathologies
- Child Nutrition and Feeding Issues
- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- LGBTQ Health, Identity, and Policy
- Psychological Treatments and Disorders
- Pediatric health and respiratory diseases
- Consumer Attitudes and Food Labeling
- Virology and Viral Diseases
- Knee injuries and reconstruction techniques
- Immunodeficiency and Autoimmune Disorders
- Infant Health and Development
- Eating Disorders and Behaviors
- SARS-CoV-2 detection and testing
- Tendon Structure and Treatment
- Adolescent Sexual and Reproductive Health
- Healthcare and Environmental Waste Management
- Infection Control and Ventilation
Universidad de Los Andes, Chile
2019-2023
Hospital Clínico de la Universidad de Chile
2013-2019
University of Chile
2013-2014
BackgroundThe Omicron variant has challenged the control of COVID-19 pandemic due to its immuno-evasive properties. The administration a booster dose SARS-CoV-2 vaccine showed positive effects in immunogenicity against SARS-CoV-2, effect that is even enhanced after second booster.MethodsDuring phase-3 clinical trial, we evaluated CoronaVac®, an inactivated administered 6 months first booster, neutralization (n = 87). In parallel, cellular immunity 45) was analyzed stimulated peripheral...
Several vaccines have been developed to control the COVID-19 pandemic. CoronaVac®, an inactivated SARS-CoV-2 vaccine, has demonstrated safety and immunogenicity, preventing severe cases. We investigate non-inferiority of two immunization schedules CoronaVac® in a trial healthy adults. A total 2302 adults were enrolled at 8 centers Chile randomly assigned vaccination schedules, receiving doses with either 14 or 28 days between each. The primary efficacy endpoints solicited adverse events...
Abstract Background Food allergy ( FA ) is a growing condition among children and it's psychological impact over the patients their caregivers well known, establishing vicious circle that perpetuates stress levels. However, psychosocial factors are not commonly included in treatments. Based on lack of evidence records about scale indicates level interaction between biopsychosocial patient–caregivers dyad for , present research aims to develop with these characteristics as helpful tool...
Background . The Scale for Psychosocial Factors in Food Allergy (SPS-FA) is based on the biopsychosocial model of health and was developed validated Chile to measure interaction between psychological variables allergy symptoms child. We sought validate this scale an English speaking population explore its relationship with parental quality life, self-efficacy, mental health. Methods Parents (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
An 11-year-old girl was transferred to the Universidad de Chile Clinical Hospital after 2.5 months of persistent and unresponsive treatment for coughlike spasms. On arrival, frequency symptoms 1 cough every 4 s, which disappeared during sleep. A multidisciplinary examination excluded allergic, viral, respiratory, epileptic, other more usual causes similar conditions. Two diagnoses (psychogenic transient vocal tic disorder) a mixed intervention were proposed leading resolution in 12 days...
The purpose of this protocol was to adapt and validate the English version Short Musculoskeletal Function Assessment (SMFA) into Chilean Spanish according World Health Organisation guidelines. This is a cross-sectional study 897 surveys patients with non-traumatic surgical orthopaedic pathologies. We analysed internal consistency, validity, acceptability, including correlation short form 36 (SF-36) medical score. validation included 900 participants response rate 99,66%, excellent...
Raising children with chronic diseases has been described as a stressing situation for carers. Several studies, especially in asthma and rhinitis, have documented psychological physiologic impact on However, little work describing the psychosocial of raising food allergy (FA) done. Consecutive carers (63) from Universidad de Chile Clinical Hospital peer support group parents (Creciendo con Alergias) were recruited evaluated anxiety, depression, perceived social personality. Carers´ reaction...
Abstract Background Several vaccines have been developed to control the COVID-19 pandemic. CoronaVac ® (Sinovac Life Sciences), an inactivated SARS-CoV-2 vaccine, has demonstrated safety and immunogenicity in previous studies, preventing severe cases. We further investigated efficacy of two immunization schedules a non-inferiority trial healthy adults. Methods This is multi-center randomized clinical trial. Healthy adults were enrolled at eight centers Chile. Participants randomly assigned...
Category: Other; Ankle; Hindfoot; Midfoot/Forefoot Introduction/Purpose: The purpose of this study is to adapt and validate the English version Short Musculoskeletal Function Assessment (SMFA) into Chilean Spanish according WHO guidelines. Methods: Cross-sectional where through 897 surveys patients with non-trauma surgical orthopaedic pathologies, internal consistency, validity acceptability were evaluated, including correlation short form 36 (SF-36) medical score. Results: preliminary...
Ankle hemiarthroplasty is a 1-piece implant system replacing the talar side of tibiotalar joint. Hemiarthroplasty offers limited bone resection and may provide easier revision options than joint-ablating procedures.Prospective, multicenter, noncomparative, nonrandomized clinical study with short term follow-up on patients undergoing ankle. Radiologic functional outcomes (Foot Outcome Score FAOS, Foot Ability Measure [FAAM], Short Form-36 Health Survey [SF-36], Musculoskeletal Functional...