Login

Sergio Bustos

ORCID: 0000-0002-6427-7266
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
A5038575465
Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Vaccine Coverage and Hesitancy
  • Viral gastroenteritis research and epidemiology
  • COVID-19 Clinical Research Studies
  • vaccines and immunoinformatics approaches

Pontificia Universidad Católica de Chile
 2022-2023

 Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adults
OPENALEX - Publications 
Constanza Méndez Hernán F. Peñaloza Bárbara M. Schultz Alejandro Piña-Iturbe Mariana Ríos and 95 more Daniela Moreno-Tapia Patricia Pereira-Sánchez Diane Leighton Claudia Orellana Consuelo Covarrubias Nicolás M. S. Gálvez Jorge A. Soto Luisa F. Duarte Daniela Rivera-Pérez Yaneisi Vázquez Alex Cabrera Sergio Bustos Carolina Iturriaga Marcela Urzúa María S Navarrete Álvaro Rojas Rodrigo Fasce Jorge Onrubia Fernández Judith Mora Eugenio Ramı́rez Aracelly Gaete-Argel Mónica L. Acevedo Fernando Valiente‐Echeverría Ricardo Soto‐Rifo Daniela Weiskopf Alba Grifoni Alessandro Sette Gang Zeng Weining Meng José Vicente González-Aramúndiz Pablo A. González Katia Abarca Felipe Melo-González Susan M. Bueno Alexis M. Kalergis Álvaro Rojas María S Navarrete Constanza del Río Dinely Del Pino Natalia Aguirre Grecia Salinas Franco Vega Acsa Salgado Thomas Quinteros Marlene Ortiz Marcela Puente Alma Muñoz Patricio Astudillo Nicole Le Corre Marcela Potı́n J.P. Catalán Melan Peralta Consuelo Zamanillo Nicole Keller Rocío Fernández Sofía Aljaro Sofía López José Tomás González Tania Weil Luz Opazo P. Rubio Muñoz Inés Estay Miguel Cantillana Liliana Carrera Matías Masalleras Paula Guzmán Francisca Aguirre Aarón Cortés Luis Federico Bátiz Javiera Pérez Karen Apablaza L. D. Yates María de los Ángeles Valdés Bernardita Hurtado Veronique Venteneul Constanza Astorga Paula Muñoz Venturelli Pablo Vial Andrea Schilling Daniela Pavez Inia Pérez Amy Riviotta Francisca González Francisca Urrutia Alejandra Del Río Claudia Asenjo Bárbara Vargas Francisca Dias de Castro Alejandra Acuña Javiera Guzmán Camila Astudillo Carlos M. Pérez Pilar Espinoza Andrea Martínez Marcela Arancibia

BackgroundThe Omicron variant has challenged the control of COVID-19 pandemic due to its immuno-evasive properties. The administration a booster dose SARS-CoV-2 vaccine showed positive effects in immunogenicity against SARS-CoV-2, effect that is even enhanced after second booster.MethodsDuring phase-3 clinical trial, we evaluated CoronaVac®, an inactivated administered 6 months first booster, neutralization (n = 87). In parallel, cellular immunity 45) was analyzed stimulated peripheral...

10.1016/j.ebiom.2023.104563 article EN cc-by-nc-nd EBioMedicine 2023-04-24
 Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adults
OPENALEX - Publications 
Felipe Melo-González Constanza Méndez Hernán F. Peñaloza Bárbara M. Schultz Alejandro Piña-Iturbe and 35 more Mariana Ríos Daniela Moreno-Tapia Patricia Pereira-Sánchez Diane Leighton Claudia Orellana Consuelo Covarrubias Nicolás M. S. Gálvez Jorge A. Soto Luisa F. Duarte Daniela Rivera-Pérez Yaneisi Vázquez Alex Cabrera Sergio Bustos Carolina Iturriaga Marcela Urzúa María S Navarrete Álvaro Rojas Rodrigo Fasce Jorge Fernández Judith Mora Eugenio Ramı́rez Aracelly Gaete-Argel Mónica Acevedo Fernando Valiente‐Echeverría Ricardo Soto‐Rifo Daniela Weiskopf Alba Grifoni Alessandro Sette Gang Zeng Weining Meng José Vicente González-Aramúndiz Pablo A. González Katia Abarca Susan M. Bueno Alexis M. Kalergis

Summary The SARS-CoV-2 Omicron variant has challenged the control of COVID-19 pandemic even in highly vaccinated countries. While a second booster mRNA vaccines improved immunity against SARS-CoV-2, humoral and cellular responses induced by an inactivated vaccine have not been studied. In context phase 3 clinical study, we report that CoronaVac ® increased neutralizing response ancestral virus yet showed poor neutralization variant. Additionally, isolated PBMCs displayed equivalent...

10.1101/2022.08.22.22279080 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-08-23
Coming Soon ...