A5087027099- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Pathology Studies
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Radiopharmaceutical Chemistry and Applications
- Advanced MRI Techniques and Applications
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Cancer, Hypoxia, and Metabolism
- Trace Elements in Health
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Peptidase Inhibition and Analysis
- MicroRNA in disease regulation
- Metastasis and carcinoma case studies
- Cardiovascular Function and Risk Factors
- Cancer Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
Tongji University
2010-2023
Shanghai Pulmonary Hospital
2010-2023
Primary pulmonary enteric adenocarcinoma (PEAC) is a rare subtype of primary lung adenocarcinoma. However, it not known whether there are any distinctive clinical or molecular features.PEACs were retrospectively identified in 28 patients from July 2014 to June 2016. We compared the clinicopathological, radiographic, and oncogenic characteristics PEAC invasive (IAC).A total 92 IAC compared. occurred more frequently males (P = .008), older .041), those with larger lesions .001), advanced stage...
The aim of this study was to develop a machine learning-based automatic analysis method for the diagnosis early-stage lung cancer based on positron emission tomography/computed tomography (PET/CT) data.
Objectives . Immune checkpoint blockers constitute the first-line treatment for advanced non-small-cell lung cancer (NSCLC) with ≥50% PD-L1 expression. In NSCLC, positivity is correlated high 18 F-fluorodeoxyglucose ( F-FDG) uptake. However, these studies only included patients undergoing surgical resection, almost all in their early stages. Moreover, differences F-FDG uptake between NSCLC (≥50%) and low (49%) expression remain unknown. We aimed to investigate association metabolic parameter...
This study sought to investigate the association between 18F-fludeoxyglucose (18F-FDG) uptake in positron emission tomography/CT (PET/CT) scans and different programmed death ligand-1 (PD-L1) expression conditions non-small cell lung cancer (NSCLC).From October 2017 December 2019, NSCLC was retrospectively identified 419 consecutive patients who underwent 18F-FDG PET/CT PD-L1 tests using 22C3 assay. The clinicopathological characteristics assessed.The frequency of PD-L1-positive tumours...
This systemic analysis was conducted to evaluate the application value of positron emission tomography/computed tomography (PET/CT) in early diagnosis lung cancer.Clinical studies evaluating PET/CT for patients underwent imaging. The histological served as standard truth.Four clinical which including 1330 with pulmonary space- occupying lesions were considered eligible inclusion. Systemic suggested that, all patients, pooled sensitivity 98.7% (1313.2/1330) and specificity...
Copper(II) ion (Cu2+) is the essential element for numerous pathophysiological processes in vivo. Copper transporter 1 (CTR1) mainly responsible maintaining Cu2+ accumulation cells, which has been found to be over-expressed inflammatory tissues. Therefore, we explored potential application of 64CuCl₂ PET imaging inflammation through targeting CTR1. The animal models H₂O₂ induced muscle and lipopolysaccaharide lung were successfully established, then imaged by small (PET/CT) post-injection...
This study aimed to investigate the relationship between standardised uptake value of free wall right ventricular myocardium (SUVrv) and left end-diastolic volume (LVEDV) among patients with heart failure reduced ejection fraction (HFrEF) coronary artery disease (CAD). retrospective included 50 CAD HFrEF scheduled for cardiac viability imaging electrocardiography-gated fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). The maximal SUVrv was...
Abstract Purpose This study aimed to identify and validate the optimal 18 F-FDG activity acquisition time for cardiac viability imaging with intravenous insulin administration based on a fixed activity. Methods Cardiac positron emission tomography (PET) images from 30 patients coronary artery disease (CAD) were retrospectively reconstructed into 900, 360, 180, 90, 45 s durations. An product of maximum standardized uptake value (SUV) myocardium segmental (SU) (MSAT) was determined through...
Abstract Purpose This study aimed to identify and validate the optimal 18 F-FDG activity acquisition time for cardiac viability imaging with intravenous insulin administration based on a fixed activity. Methods Cardiac positron emission tomography (PET) images from 30 patients coronary artery disease (CAD) were retrospectively reconstructed into 900, 360, 180, 90, 45 s durations. An product of maximum standardized uptake value (SUV) myocardium segmental (SU) (MSAT) was determined through...