- Spine and Intervertebral Disc Pathology
- Total Knee Arthroplasty Outcomes
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Renal Transplantation Outcomes and Treatments
- Pelvic and Acetabular Injuries
- Blood transfusion and management
- Musculoskeletal pain and rehabilitation
- Knee injuries and reconstruction techniques
- Shoulder Injury and Treatment
- Venous Thromboembolism Diagnosis and Management
- Pain Mechanisms and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Spinal Hematomas and Complications
- Pancreatic function and diabetes
- Burn Injury Management and Outcomes
- Advanced Sensor and Energy Harvesting Materials
- Periodontal Regeneration and Treatments
- Interdisciplinary Research and Collaboration
- Organ Donation and Transplantation
- Advanced Materials and Mechanics
- Circular RNAs in diseases
- Spondyloarthritis Studies and Treatments
- Veterinary Orthopedics and Neurology
- Diabetes and associated disorders
Beijing Jishuitan Hospital
2009-2025
Peking University
2009-2025
Capital Medical University
2025
Second Affiliated Hospital of Xi'an Jiaotong University
2025
Beijing National Laboratory for Molecular Sciences
2024
Tianjin Hospital
2012-2023
Tianjin University
2022
Central Hospital of Zibo
2021
Xuzhou Medical College
2020
Tianjin University of Traditional Chinese Medicine
2018
Abstract Objectives Large bone defects are a common, debilitating clinical condition that have substantial global health and economic burden. Bone tissue engineering technology has become one of the most promising approaches for regenerating defective bones. In this study, we fabricated naringin‐inlaid composite silk fibroin/hydroxyapatite (NG/SF/HAp) scaffold to repair defects. Materials Methods The salt‐leaching was used fabricate NG/SF/HAp scaffold. cytocompatibility assessed using...
Hypertrophic scars are a type of pathological scar that can cause discomfort, pain, and itching. The assessment hypertrophic depends largely on the clinician's long-term experience. Computer-aided greatly improve efficiency accuracy assessment. In this paper, we propose deep neural network-based method for degree pigmentation vascularity using real images. Firstly, large amount images were collected to produce dataset including patients all ages distribution lesions in different parts body....
This study aims to explore the association between Life's Essential 8 (LE8) and stroke all-cause mortality, compare whether it has an advantage over Simple 7 (LS7). investigated data from NHANES spanning 1999 2018. The LE8 was categorized as low, moderate high cardiovascular health (CVH). LS7 score inadequate, average, or optimal. Weighted logistic regression restricted cubic spline (RCS) were used examin correlations. Receiver operating characteristic (ROC) curves employed detect accuracy...
Over 90% of cancer patients succumb to metastasis, yet conventional frontline therapy struggles halt the progression metastatic tumors. Targeted radionuclide therapy, which delivers radiation precisely tumor sites, shows promise for treating metastasis. The rational design a prodrug activation platform using radionuclides would be an ideal approach synergize chemotherapy with targeted it has not been established. Here, we present therapy-induced cleavage chemistry that enables controlled...
Mono-segment transpedicular fixation is a method for the treatment of certain types thoracolumbar spinal fracture. Finite element models were constructed to evaluate biomechanics mono-segment Spinal motion (T10–L2) was scanned and used establish models. The superior half cortical bone T12 removed cancellous body assigned material properties injured mimic vertebral Transpedicular T11 performed produce model; L1 fixed short-segment model. Motion differences between functional units von Mises...
The growing rod technique was applied in the treatment of early onset scoliosis (EOS) with promising outcomes and many complications at same time. We reviewed data from literatures to compare results single rods dual achieve a clear understanding this technique. PubMed, Embase, MEDLINE, ScienceDirect, CNKI, Wanfang Data, CQVIP were searched electronically until March 2016 using "growing rod" "early scoliosis" as major search terms. Also, we manually other relevant conference proceedings. Two...
Abstract Fracture healing is a complex bone formation process, and neovascularization may contribute to new regeneration. The circulating endothelial progenitor cell (EPC) mobilization homing could involve in vasculogenesis. In this study, we investigate the changes of EPC during fracture healing, possible contribution EPCs increased healing. number was monitored twenty‐four patients with long traumatic within first 48 h at 3, 5, 10, 14 days post‐fracture. mononuclear cells which isolated...
Studies have indicated that interleukin 23 (IL-23) plays an important role in many inflammatory- and autoimmune-related diseases. However, there is little knowledge about IL-23 lumbar disc herniation (LDH). Thus, this study, we aimed to find out whether expressed intervertebral discs (IVDs) what roles it may play.Human IVD tissues were collected from 29 LDH patients 8 vertebral fracture (normal control, NC group). According the integrity of annulus fibrosus, divided into two groups: R group...
The establishment of Modic changes (MCs) in animal model was vital for research MCs. Fifty-four rabbits were divided into a sham group, muscle embedment group (ME group) and nucleus pulposus (NP) (NPE group). In the NPE discs exposed by lumbar anterolateral surgical approach. A needle used to puncture L5 vertebral body close endplate. NP extracted syringe from L1/2 intervertebral then injected drilled hole subchondral bone. had same procedure drill method as group. Some pieces put ME but...
Objective: To determine the correlation between degree of radiculalgia and counts T lymphocyte subsets in peripheral blood patients with lumbar disc herniation. Methods: Forty‐nine herniation (group A) were divided into three subgroups according to Visual Analogue Scale (VAS) pain scores A 1 : n = 12, VAS 0–4.0; 2 24, 4.1–7.0; 3 13, 7.1–10.0. Twenty health donors who volunteered be involved study comprised control group B). Peripheral various measured each group. Results: (i) The CD4+...
Lumbar disc herniation (LDH) is a common cause of lumbosacral radiculopathy. An autoimmune response to herniated nucleus pulposus (NP) has been suggested play an important role in the initiation Interleukin-17 (IL-17) cytokine associated with inflammation and autoimmunity. The presence IL-17 studied patients LDH; however, extensive investigation into expression different pathologies LDH not yet conducted. aim present study was investigate neovascularization hypertrophic chondrocytes...