A5081544704- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Cardiovascular and Diving-Related Complications
- Lipoproteins and Cardiovascular Health
- Cardiac pacing and defibrillation studies
- Cardiac tumors and thrombi
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Platelet Disorders and Treatments
- Heart Failure Treatment and Management
- Inflammatory mediators and NSAID effects
- Chronic Kidney Disease and Diabetes
- Cardiac Ischemia and Reperfusion
- Renal Diseases and Glomerulopathies
- Peripheral Artery Disease Management
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cerebrovascular and Carotid Artery Diseases
Azienda Ospedaliera San Camillo-Forlanini
2023-2024
Carlo Forlanini Hospital
2022-2024
Sapienza University of Rome
2012-2023
Azienda Ospedaliera Sant'Andrea
2023
Ospedale generale di zona San Camillo Treviso
2023
IRCCS San Camillo Hospital
2021-2022
Policlinico Umberto I
2012-2020
Ospedale Maggiore
2018-2019
Ferrarotto Hospital
2013
University of Catania
2013
There are limited data regarding the impact of final kissing balloon (FKI) in patients treated with percutaneous coronary intervention using ultrathin stents left main or bifurcations.All undergoing bifurcations enrolled RAIN registry (Very Thin Stents for Patients With MAIN BiF Real Life: The RAIN, a Multicenter Study) evaluating were included. Major adverse cardiac event (a composite all-cause death, myocardial infarction, target lesion revascularization, and stent thrombosis) was primary...
The aim of this multicentre study was to investigate the in-hospital and midterm outcomes rotational atherectomy (RA) followed by metallic stent implantation.Between 2002 2013, 1,176 de novo lesions with calcified coronary treated RA implantation at nine institutions were assessed. Patients ST-segment elevation myocardial infarction (STEMI) within 30 days, cardiogenic shock before procedure, thrombus, in-stent restenosis excluded from current analysis. In-hospital major adverse cardiac...
Objectives We aimed to investigate procedural feasibility and outcomes associated with planned rotational atherectomy (RA) for severely calcified coronary lesions. Background: Limited data are available addressing the benefits of RA compared provisional RA. Methods Between 2002 2013, all patients lesions treated by were enrolled. Of these, (358 patients) those (309 patients). Results In‐hospital major adverse cardiovascular events (MACE) tended be better in group (unadjusted OR: 0.76; 95%...
Aims:The safety and efficacy of rotational atherectomy (RA) in patients presenting with non-ST-elevation myocardial infarction (NSTE-ACS) remain to be defined.The aim our study was assess the RA NSTE-ACS reference both short-and long-term follow-up. Methods results:This an observational retrospective registry which enrolled all consecutive undergoing RA, comparing stable angina (SA) NSTE-ACS.In addition, ACS were matched those not RA.The primary endpoint angiographic success.Procedural...
High on-treatment platelet reactivity (HTPR) is associated with adverse outcomes. We aim to compare the novel thienopyridine prasugrel versus double-dose clopidogrel in patients HTPR and explore interaction between CYP2C19 genotype both drugs.Consecutive stable undergoing percutaneous coronary intervention were screened Multiplate Analyzer P2Y12 assay, defining as area under curve >450. Those randomized (10 mg/day) or high-dose (150 for 2 weeks then crossed-over to, respectively, prasugrel,...
Background Rotational atherectomy (RA) is relatively contraindicated in patients with lesions ≥25 mm of length. Aim this study was to evaluate RA safety and efficacy subset new technology devices. Methods Results From April 2002 August 2013, the ROTATE registry included all consecutive undergoing 8 centres. They were divided into shorter lesion group (SLG, < 25 mm) longer (LLG, ≥ mm). The angiographic success (AS) primary end point. Procedural complications (PC), a composite point...
The epidemiology and management of patients with acute coronary syndromes (ACSs) have evolved. We aimed to describe recent demographics therapeutic changes in the Italian ACS population. analyzed data from 2 multicenter consecutive registries (the EYESHOT [EmploYEd antithrombotic therapies Syndromes HOspitalised iTalian cardiac care units] START-ANTIPLATELET registries) enrolling between December 2013 June 2016. An overall population 3756 was enrolled: 2585 1171 START-ANTIPLATELET. Compared...
Transcatheter aortic valve implantation (TAVI) has been proposed to treat older surgical high-risk patients with severe symptomatic stenosis. There are no data regarding short-term and long-term infectious complications in these patients. The objective of this study was define the incidence, aetiology outcome early late following TAVI compared >65 years old undergoing traditional replacement (SAR). This a prospective observational evaluating all consecutive who underwent or SAR. Follow up...
Objective In the setting of reperfused ST-elevation myocardial infarction (STEMI), increased production reactive oxygen species (ROS) contributes to reperfusion injury. Among ROS, hydrogen peroxide (H 2 O ) showed toxic effects on human cardiomyocytes and may induce microcirculatory impairment. Glutathione (GSH) is a water-soluble tripeptide with potent oxidant scavenging activity. We hypothesised that infusion GSH before acute reoxygenation might counteract deleterious H generation...
Abstract Background The relationship between high postprocedural mean gradient (ppMG) and clinical events following mitral valve transcatheter edge‐to‐edge repair (MV‐TEER) in patients with degenerative regurgitation (DMR) is still debated. Aim purpose of this study was to evaluate the effect elevated ppMG after MV‐TEER on DMR at 1‐year follow‐up. Methods included 371 treated enrolled “Multi‐center Italian Society Interventional Cardiology (GISE) registry trans‐catheter treatment...
Abstract Background The PARIS risk score (PARIS‐rs) and percutaneous coronary intervention complexity (PCI‐c) predict clinical procedural residual ischemic following PCI. Their accuracy in patients undergoing unprotected left main (ULM) or bifurcation PCI has not been assessed. Methods predictive performances of the PARIS‐rs (categorized as low, intermediate, high) PCI‐c (according to guideline‐endorsed criteria) were evaluated 3,002 ULM/bifurcation with very thin strut stents. Results After...
Objectives To compare the safety and efficacy of Axxess™ biolimus‐eluting stent with second‐generation drug‐eluting (DES) in treatment bifurcation lesions. Background The is a dedicated stent, designed to cover lesion at carina level. Methods Between April 2012 August 2014, 165 patients de novo lesions were treated (Axxess group). A propensity‐score matched group DES same period was selected (Control primary objectives (1) procedural complication rate, including side branch (SB) occlusion...
To evaluate the performance of biolimus-eluting stent (BES) in patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) a real world clinical scenario.Randomized studies suggest that BES biodegradable polymer is more effective and safe than early generation stents STEMI.We included all consecutive STEMI PCI this prospective, multicenter registry. The primary endpoint study was rate major adverse cardiac events (MACE), composite death,...
Abstract Background Complete revascularization (CR) of nonculprit lesions (NCL) is strongly recommended in patients with ST‐elevation myocardial infarction (STEMI) and multivessel coronary artery disease (MVD), but no definitive evidence available regarding which diagnostic strategy should be preferred. Instantaneous wave‐free ratio (iFR) has never been investigated this setting. We aimed to describe clinical outcomes a cohort undergoing iFR‐guided CR. Methods Following primary percutaneous...
To evaluate the short- and long-term clinical echocardiographic outcomes of percutaneous closure patent foramen ovale (PFO) with an atrial septal aneurysm (ASA) using 2 different devices.We enrolled 100 patients PFO ASA. Fifty consecutive had transcatheter Gore Cardioform occluder (GSO) (Gore Medical) a second group 50 Amplatzer (APO) (Abbott). A transthoracic follow-up was performed at 1, 3, 6, 12 months after implant procedure. The primary endpoint incidence moderate-to-severe residual...
We report a case of an 81-years-old male, recently implanted with Core Valve (CV) prosthesis and admitted to the ER for acute coronary syndrome. Coronary angiography revealed patency artery by-pass grafts but was impossible cannulate left main "imprisoned" by CV struts. Aortography showed excessive gap between struts ostium. To cross struts, we developed "proboscis" catheter cutting away proximal end 7F JL 4 putting inside 5F Heartrail catheter. The following angiograms critical stenosis in...
Left ventricular assist device (LVAD) obstruction can be a dramatic and life-threatening complication in patients with advanced heart failure (HF). Despite surgical redo is often required these patients, it associated high risk of periprocedural negative outcome. We report the case 68-year-old male thrombotic stenosis LVAD proximal outflow-graft. Following Heart Team debate, percutaneous intervention was planned during veno-arterial Extra Corporeal Membrane Oxygenation (ECMO) assistance. To...
Introduction The treatment of patients with cardiogenic shock (CS) encompasses several health technologies including Impella pumps and venoarterial extracorporeal membrane oxygenation (VA-ECMO). However, while they are widely used in clinical practice, information on resource use quality life (QoL) associated these devices is scarce. aim this study is, therefore, to collect comparatively assess socioeconomic data versus VA-ECMO for the severe CS, ultimately conduct both a cost-effectiveness...