Kaiwen Liu

ORCID: 0000-0002-4988-4367
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About
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Research Areas
  • Bone Metabolism and Diseases
  • Bone health and treatments
  • S100 Proteins and Annexins
  • Hip and Femur Fractures
  • Bone health and osteoporosis research
  • Pain Mechanisms and Treatments
  • Medical Imaging and Analysis
  • Cardiac Valve Diseases and Treatments
  • Spine and Intervertebral Disc Pathology
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac pacing and defibrillation studies

Qilu Hospital of Shandong University
2023-2024

Beijing Anzhen Hospital
2024

Capital Medical University
2024

Abstract Osteoporosis is a systemic metabolic bone disorder for which inflammatory cytokines play an important role. To develop new osteoporosis treatments, strategies improving the microenvironment osteoblast and osteoclast balance are needed. Tumor necrosis factor-α (TNF-α) plays role in initiation development of osteoporosis. Atsttrin engineered protein derived from growth factor, progranulin (PGRN). The present study investigates whether affects formation formation. Here we show inhibits...

10.1038/s42003-023-05635-y article EN cc-by Communications Biology 2023-12-11

Low back pain (LBP) caused by nucleus pulposus degeneration and calcification leads to great economic social burden worldwide. Unexpectedly, no previous studies have demonstrated the association underlying mechanism between tissue formation. Secreted Phosphoprotein 1 (SPP1) exerts crucial functions in bone matrix mineralization calcium deposition. Here, a novel function of SPP1 is reported, namely that it can aggravate cells (NPs) negatively regulating extracellular homeostasis. The...

10.1002/advs.202411162 article EN cc-by Advanced Science 2024-12-25

Background The reaserch of artificial intelligence (AI) model for predicting spinal refracture is limited to bone mineral density, X‐ray and some conventional laboratory indicators, which has its own limitations. Besides, it lacks specific indicators related osteoporosis imaging factors that can better reflect quality, such as computed tomography (CT). Objective To construct a novel based on turn‐over markers CT identify patients who were more inclined suffer spine refracture. Methods images...

10.1111/os.14155 article EN cc-by-nc-nd Orthopaedic Surgery 2024-07-01

To compare the efficacy of isolated off-pump coronary artery bypass grafting (OPCABG) and (CABG) plus mitral valve plasty (MVP) in treating heart disease with moderate ischemic regurgitation to find a better surgical method.

10.21470/1678-9741-2023-0254 article EN PubMed 2024-11-28

Abstract Osteoporosis is a systemic metabolic bone disease. believed to be inflammatory condition in which cytokines play an important role. Among these molecules, tumor necrosis factor-α (TNF-α) plays role the initiation and development of osteoporosis. Atsttrin engineered protein derived from growth factor, progranulin (PGRN). It’s well accepted inhibits TNF-α’s function by binding receptors (TNFRs). The aim this study was investigate Present use cell TRAP staining determine...

10.21203/rs.3.rs-2565180/v1 preprint EN cc-by Research Square (Research Square) 2023-02-20
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