Zhenchuan Liu

ORCID: 0000-0002-1503-4516
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About
Contact & Profiles
Research Areas
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Immune cells in cancer
  • Neurological Disease Mechanisms and Treatments
  • Bone Metabolism and Diseases
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Spine and Intervertebral Disc Pathology
  • Eicosanoids and Hypertension Pharmacology
  • Pain Mechanisms and Treatments
  • Acute Ischemic Stroke Management
  • Kruppel-like factors research
  • Neuroinflammation and Neurodegeneration Mechanisms

Linyi People's Hospital
2019-2024

Qilu Hospital of Shandong University
2024

The cervical spine's mobility affects the compression level of cord which varies with dynamic positioning. High signal on MRI T2-weight imaging (MRI-T2WI) indicates a poorer prognosis. This study investigates relationship between high-signal intensity MRI-T2WI and change using kinematic MRI. objective this was to explore changes in degree spinal during flexion-extension motions identify risk factors linked occurrence high signals. We collected data patients who underwent surgical treatment...

10.1186/s13018-025-05715-1 article EN cc-by-nc-nd Journal of Orthopaedic Surgery and Research 2025-04-09

Intracerebral hemorrhage (ICH) could trigger inflammatory responses. However, the specific role of proteins in pathological mechanism, complications, and prognosis ICH remains unclear. In this study, we investigated expression 92 plasma inflammation-related patients with (n = 55) healthy controls 20) using an Olink inflammation panel discussed relation to severity stroke, clinical 30-day mortality, 90-day outcomes. Our result showed that six were upregulated compared controls, while...

10.1021/acs.jproteome.4c00311 article EN Journal of Proteome Research 2024-09-03

Low back pain (LBP) caused by nucleus pulposus degeneration and calcification leads to great economic social burden worldwide. Unexpectedly, no previous studies have demonstrated the association underlying mechanism between tissue formation. Secreted Phosphoprotein 1 (SPP1) exerts crucial functions in bone matrix mineralization calcium deposition. Here, a novel function of SPP1 is reported, namely that it can aggravate cells (NPs) negatively regulating extracellular homeostasis. The...

10.1002/advs.202411162 article EN cc-by Advanced Science 2024-12-25

The popular traditional Chinese medicine (TCM) compound FYTF-919 (Zhong Feng Xing Nao prescription) may improve outcome from acute intracerebral hemorrhage (ICH) through effects on brain edema, hematoma absorption, and the immune system. This study is to assess whether safe effective as compared matching placebo treatment in patients with ICH.

10.1159/000534761 article EN cc-by-nc Cerebrovascular Diseases 2023-10-26
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