- Autoimmune Neurological Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- RNA regulation and disease
- Cerebrospinal fluid and hydrocephalus
- Global Public Health Policies and Epidemiology
- Brain Metastases and Treatment
- Global Maternal and Child Health
- Cerebral Palsy and Movement Disorders
- Congenital Heart Disease Studies
- Neurological Disease Mechanisms and Treatments
- Telemedicine and Telehealth Implementation
- Cardiovascular Issues in Pregnancy
- Global Health and Surgery
- Herpesvirus Infections and Treatments
- Diabetes Treatment and Management
- Mycobacterium research and diagnosis
- Clinical Reasoning and Diagnostic Skills
- Healthcare Systems and Reforms
- Immunotoxicology and immune responses
- Glioma Diagnosis and Treatment
- Neurology and Historical Studies
- Diabetes and associated disorders
- Metabolomics and Mass Spectrometry Studies
- Cerebrovascular and genetic disorders
- History of Medical Practice
Hôpital de l'Enfant-Jésus
2025
Université Laval
2025
University of California, San Francisco
2023-2024
Universidad Católica de Santa Fe
2024
Tufts Medical Center
2020-2021
Centre Hospitalier d'Angoulême
2021
Dartmouth College
2019
Vitamin B12 is critical for hematopoiesis and myelination. Deficiency can cause neurologic deficits including loss of coordination cognitive decline. However, diagnosis relies on measurement vitamin in the blood, which may not accurately reflect concentration brain. Using programmable phage display, we identified an autoantibody targeting transcobalamin receptor (CD320) a patient with progressive tremor, ataxia, scanning speech. Anti-CD320 impaired cellular uptake cobalamin (B12) vitro by...
Summary Recent studies have shown that sensory rhythmic stimulation can enhance executive functions by synchronizing, entraining, oscillations within higher-order cortical networks. However, whether this entrainment extends to subcortical structures and shapes human behavior remains unclear. In a first experiment, we used intracranial EEG recordings in epileptic patients during visual search task. While neutral induced moderate entrainment, demonstrated 5 Hz negative-valence significantly...
<h3>Objective</h3> There is increasing attention to cardiovascular diseases in low-income countries. However, little known about heart failure (HF) rural areas, where most of the populations countries live. We studied HF epidemiology, care delivery and outcomes Haiti. <h3>Methods</h3> Among adults admitted with a Haitian tertiary hospital during 12-month period (2013–2014), we clinical characteristics short-term including length stay, inhospital death outpatient follow-up rates....
<strong>Background:</strong> Poverty is a major barrier to healthcare access in low-income countries. The degree of equitable for noncommunicable disease (NCD) patients not known rural Haiti. <strong>Objectives:</strong> We evaluated the poverty distribution among receiving care an NCD clinic Haiti compared with community and assessed associations sex distance from health facility. <strong>Methods:</strong> performed cross-sectional study NCDs attending public-sector center 2013–2016,...
Abstract Vitamin B12 is critical for hematopoiesis and myelination. 1 Deficiency can cause neurologic deficits including loss of coordination, spasticity, cognitive decline. 2,3,4 However, diagnosis relies on vitamin measurement in the blood which may not accurately reflect levels brain. Here, we discovered an autoimmune deficiency restricted to central nervous system (CNS), termed (ABCD). Using programmable phage display, identified autoantibody targeting transcobalamin receptor (CD320) a...
From 2004 to 2015, the average number of neurologists in high-income countries increased from 3 5.14 per 100,000 population; low-income (LICs) remained static at 0.03 100,000.1,2 This disparity is likely due large part paucity neurology training programs LICs,3 leading physicians interested train abroad, where many stay (the brain drain phenomenon).4 Neurologic disorders are cause disability-adjusted life-years and second mortality worldwide,5 requiring expansion global workforce. Here we...
To assess the host immune response in focal cerebral arteriopathy of childhood.
We investigated cerebrospinal fluid (CSF) host transcriptomic differences in TBM survivors compared to non-survivors as a means of understanding the role that response plays surviving
To assess the effects of secreted factors from human B cells on neuronal viability in vitro.
April 26, 2018April 10, 2018Free AccessHead CT Findings at a Public Hospital in Rural Haiti: Retrospective Analysis of 3614 Scans (P5.157)Yannis Valtis, Maggie Cochran, Louine Martineau, Bregenet Lamour, Jeffrey Mendel, and Aaron BerkowitzAuthors Info & AffiliationsApril 2018 issue90 (15_supplement) Letters to the Editor