A5034876062- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Cardiovascular Effects of Exercise
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiomyopathy and Myosin Studies
- Cardiac Valve Diseases and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Diabetes Treatment and Management
- Retinoids in leukemia and cellular processes
- Parathyroid Disorders and Treatments
- Cancer Immunotherapy and Biomarkers
- Acne and Rosacea Treatments and Effects
- Congenital Heart Disease Studies
- Pericarditis and Cardiac Tamponade
- Takotsubo Cardiomyopathy and Associated Phenomena
- Viral Infections and Immunology Research
- Metabolism, Diabetes, and Cancer
- RNA regulation and disease
- Antiplatelet Therapy and Cardiovascular Diseases
University of Bari Aldo Moro
2021-2025
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2021-2024
Presidio Ospedaliero
2024
University of Rome Tor Vergata
2024
Ospedale Pediatrico Giovanni XXIII
2023
Polyclinic General Hospital
2023
University of Foggia
2007-2011
Cardiac magnetic resonance (CMR) imaging has witnessed substantial progress with the advent of parametric mapping techniques, most notably T1 and T2 mapping. These advanced techniques provide valuable insights into a wide range cardiac conditions, including ischemic heart disease, cardiomyopathies, inflammatory valve athlete’s heart. Mapping could be first sign myocardial injury oftentimes precedes symptoms, changes in ejection fraction, irreversible remodeling. The ability to offer...
Background: Several drugs are emerging as potential therapeutic resources in the context of chronic heart failure (CHF), although their impact on daily clinical practice remains unknown. The objective this study was to investigate theoretical eligibility for vericiguat and omecamtiv mecarbil (OM) a real-world outpatient setting. Methods: A cross-sectional observational conducted, enrolling all patients with CHF who had at least one visit between January 2023 2024 dedicated clinic tertiary...
Acute coronary syndrome (ACS) and stroke are interconnected conditions that often share risk factors such as atherosclerosis, thrombosis, systemic inflammation. When these events occur simultaneously, they present unique diagnostic therapeutic challenges. This review explores the pathophysiological mechanisms linking ACS stroke, including common pathways like plaque instability, cardioembolism, endothelial dysfunction, while highlighting distinct features of ischemic hemorrhagic strokes. The...
(1) Background: Glucagone-Like Peptide-1 Receptor Agonists (GLP-1 RAs) are incretine-based medications recommended in the treatment of type 2 Diabetes Mellitus (DM2) with atherosclerotic cardiovascular disease (ASCVD) or high very (CV) risk. However, knowledge direct mechanism GLP-1 RAs on cardiac function is modest and not yet fully elucidated. Left ventricular (LV) Global Longitudinal Strain (GLS) Speckle Tracking Echocardiography (STE) represents an innovative technique for evaluation...
Aim: Micra AV represents a leadless endocardial pacing system able to detect atrial contractions providing atrioventricular synchrony. A reduction of myocardial contractility may be detected in case first-degree block (AVB). Materials & methods: In six patients with AVB (PQ interval ≥220 msec) was evaluated the left ventricle global longitudinal strain (LV GLS) by speckle tracking (ST) echocardiography during single-lead sensing ventricular (VDD) stimulation as compared spontaneous rhythm...
Arrhythmic risk stratification in patients with Lamin A/C gene (LMNA)-related cardiomyopathy influences clinical decisions. An implantable cardioverter defibrillator (ICD) should be considered an estimated 5-year of malignant ventricular arrhythmia (MVA) ≥10%. The prediction score for MVA includes non-missense LMNA mutations, despite their role as established factor sudden cardiac death (SCD) has been questioned several studies. purpose this study is to investigate features and find...
Telemedicine and remote monitoring devices, including implantable loop recorders (ILR), are increasingly adopted in the cardiologic setting. These valuable tools arrhythmic stratification of patients at risk sudden cardiac death, providing a tailored therapeutic management to prevent lethal arrhythmias. We report case an asymptomatic 18-year-old boy with family history syncope arrest, who had diagnosis Brugada syndrome inducible type 1 pattern carrier missense mutation SCN5A gene. In light...
Cardiomyopathies (CMPs) are a group of myocardial disorders that characterized by structural and functional abnormalities the heart muscle. These occur in absence coronary artery disease (CAD), hypertension, valvular disease, congenital disease. CMPs an increasingly important topic field cardiovascular diseases due to complexity their diagnosis management. In 2023, ESC guidelines on cardiomyopathies were first published, marking significant progress field. The growth techniques such as...
Abstract Background Immune checkpoint inhibitors (ICIs) such as Ipilimumab and Nivolumab have revolutionized the field of cancer therapy. These monoclonal antibodies help to reinforce antitumor immunity, resulting in robust activation immune system which promotes tumor cell death. T–cell–targeted immunomodulators are now widely used treatment about 50 types, including metastatic Renal Cell Carcinoma (RCC). However, responses by ICIs, especially when combination, may lead systemic...
Abstract Introduction Takotsubo Syndrome (TTS) is characterized by a transient left ventricle (LV) systolic dysfunction usually occurring in postmenopausal women after intense physical or emotional stress. Case Report A 75–year–old female patient without history of heart disease was admitted to our hospital for sudden onset painful muscle spasms associated with burning sensation hands and feet. She also reported peri–oral numbness, dysphagia nausea. received, at the age 68, diagnosis...
One of the most common complications tricuspid valve replacement is atrioventricular block (AVB), often requiring permanent pacing. The endocardial pacemaker lead, placed in right ventricle, may sometimes interfere with implanted prosthesis, causing its early dysfunction and need for alternative sites To best our knowledge, we present first case a successful combined percutaneous procedure consisting implantation two leads coronary sinus univentricular bifocal pacing transcatheter...
The presence of inflammatory reaction in peri-tumoural connective tissue is generally considered as a defense mechanism against cancer, but inflammation malignant transformation and early steps oncogenesis has been recently proven to play supporting aggravating role some carcinomas. Aims this retrospective study were evaluate OSCCs the independent association peri-tumoral infiltrate (PTI) with local recurrence (LR) or survival outcome, verify whether PTI can be marker prognosis. Data from...
Isotretinoin or 13-cis-retinoic acid (RA) is one of the most effective and widely used drugs for treatment severe acne vulgaris. Despite being deemed safe, no definite consensus has been reached on cardiovascular risk RA derivatives. We report a case heart failure due to dilated cardiomyopathy (DCM) concomitant renal infarction occurring after 5 months isotretinoin use in previously healthy 18-year-old male. The patient, with history vulgaris, presented our emergency department left iliac...
Cangrelor, the first intravenous P2Y12 inhibitor (P2Y12-I), has been approved on basis of three large RCTs from CHAMPION program which nevertheless have criticized for low bleeding risk enrolled patients, quote chronic coronary syndromes, and use Clopidogrel as control arm even in setting acute syndromes (ACS). We sought to investigate, ACS, comparative performance Cangrelor terms in-hospital ischemic haemorrhagic outcomes compared with current gold-standard oral P2Y12-I. The study...