A5029341846- Antibiotic Resistance in Bacteria
- Infective Endocarditis Diagnosis and Management
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Bacterial Infections and Vaccines
- COVID-19 and healthcare impacts
- Antimicrobial Resistance in Staphylococcus
- Orthopedic Infections and Treatments
- Hepatitis B Virus Studies
- Microscopic Colitis
- Clostridium difficile and Clostridium perfringens research
- Streptococcal Infections and Treatments
- Infectious Diseases and Tuberculosis
- Antifungal resistance and susceptibility
- SARS-CoV-2 and COVID-19 Research
- Burkholderia infections and melioidosis
- Healthcare Systems and Challenges
- Gastrointestinal motility and disorders
- Actinomycetales infections and treatment
- Urinary Tract Infections Management
- Enterobacteriaceae and Cronobacter Research
- Infection Control and Ventilation
- Salmonella and Campylobacter epidemiology
- Vibrio bacteria research studies
- COVID-19 Impact on Reproduction
Beaumont Hospital
2016-2024
Royal College of Surgeons in Ireland
2017-2024
Western University
2019
University Hospital Galway
2011-2012
Streptococci are not an infrequent cause of periprosthetic joint infection (PJI). Management by debridement, antibiotics, and implant retention (DAIR) is thought to produce a good prognosis, but little known about the real likelihood success. A retrospective, observational, multicenter, international study was performed during 2003–2012. Eligible patients had streptococcal PJI that managed with DAIR. The primary endpoint failure, defined as death related infection, relapse/persistence or...
Extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae infections are associated with delayed initiation of appropriate treatment, poor outcomes and increased hospital stay expense. Although initially healthcare settings, more recent international reports have shown increasing isolation ESBLs in the community. Both community ESBL epidemiology Ireland poorly defined.This report describes clinical laboratory data from three hospitals over 4.5 years. All significant isolates were...
We describe a case of brucellosis in man his 20s, who presented to the emergency department with 1-month history fevers, dry cough and knee pain. Blood cultures were positive after 55 hours Ochrobactrum daejeonense was identified on matrix-assisted laser desorption/ionisation time flight (MALDI-TOF) mass spectrometry. spp are Gram-negative organisms that phylogenetically related Brucella but commercially available MALDI-TOF libraries cannot distinguish between two genera. Further blood for...
Abstract Objectives: Molecular epidemiological description of an OXA-48 CPE outbreak affecting a tertiary-care hospital ward in Ireland over extended period (2018–2019). Methods: Microbiological testing and whole-genome sequencing (WGS) were performed on all 56 positive case isolates. Results: In total, 7 different species identified: Enterobacter hormaechei (n = 35, 62.5%), Escherichia coli 12, 21.4%), Klebsiella pneumoniae 5, 8.9%), oxytoca 1, 1.8%), michiganensis Citrobacter freundii...
Abstract. We describe a case of 60-year old male who developed an acute prosthetic joint infection (PJI) the knee, secondary to erysipelas lower leg due beta-hemolytic Group G streptococci. As it is unknown how often this phenomenon occurs in patients with implants and which are most prone develop complication, we analyzed: i) incidence development PJI these ii) clinical characteristics streptococcal during episode erysipelas/cellulitis. Based on retrospective analysis implant situ...
Shared accommodation, equipment, and staff movement enhance healthcare transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [[1]Rickman H.M. Rampling T. Shaw K. Martinez-Garcia G. Hail L. Coen P. et al.Nosocomial disease 2019: a retrospective study 66 hospital-acquired cases in London teaching hospital.Clin Infect Dis. 2020 Jun 20; https://doi.org/10.1093/cid/ciaa816Crossref PubMed Scopus (157) Google Scholar]. Pre- or asymptomatic 2019 (COVID-19) poses silent risk....
The recently published European Society of Cardiology guidelines for infective endocarditis management recommends daptomycin combination therapy the treatment staphylococcal in severe penicillin allergy, rather than monotherapy. We discuss evidence-base behind this recommendation, highlighting concerns regarding lack robust clinical studies, increased cost and logistical considerations, adverse effects therapy. Although further studies are required to elucidate role versus monotherapy these...
Acute pancreatitis (AP) is an inflammatory condition of the pancreas that varies widely in both clinical presentation and severity. Current international guidelines do not recommend use prophylactic antimicrobials AP. To review compliance antimicrobial prescribing AP with guidelines. We conducted a retrospective patients admitted between 1st January 2021 31st December 2021, Beaumont Hospital, Dublin, Ireland. For each case identified, 2012 Revised Atlanta Criteria for were then applied on...
The primary aim of this study was to review the diagnosis, management and outcome Candida meningitis/ventriculitis in our hospital over a ten-year period.We retrospectively reviewed all culture 18s rRNA nucleic acid positive CSF specimens processed between 1st January 2010 31st December 2020. Patient records were subsequently assess significance isolate.Of 851 culture-positive cerebrospinal fluid (CSF) specimens, spp. isolated from 29 (3.4%), representing infection 12 patients. One...
Carbapenemase-producing enterobacterales (CPE) have disseminated worldwide, with the enzyme OXA-48 (so-named by its hydrolysis of antibiotic oxacillin) emerging as most prevalent carbapenem...
The aim of this submission is to demonstrate the need for broad antimicrobial therapy, including empiric anti-fungal if rim-enhancing lesions are noted on cerebral imaging.A retrospective microbiological and radiologic review management a rare case multiple Scedosporium apiospermum vancomycin-resistant Enterococcus faecium intra-cranial abscesses in an immunocompromised patient was performed. A manual chart assessing clinical epidemiologic characteristics completed procedures operative...