A5071171015- Bryophyte Studies and Records
- Plant Molecular Biology Research
- Single-cell and spatial transcriptomics
- Plant nutrient uptake and metabolism
- Legume Nitrogen Fixing Symbiosis
- Plant Parasitism and Resistance
- Photosynthetic Processes and Mechanisms
- Material Properties and Applications
- RNA and protein synthesis mechanisms
- Coastal wetland ecosystem dynamics
- Cell Image Analysis Techniques
- Peatlands and Wetlands Ecology
- Immune Cell Function and Interaction
- Nematode management and characterization studies
- Engineering and Materials Science Studies
- Botany and Plant Ecology Studies
- Chromosomal and Genetic Variations
- T-cell and B-cell Immunology
- Plant and Biological Electrophysiology Studies
- Advanced Fluorescence Microscopy Techniques
- Marine and coastal plant biology
- Mitochondrial Function and Pathology
University of Zurich
2019-2024
Finnish Museum of Natural History
2024
University of Helsinki
2024
German Center for Neurodegenerative Diseases
2023-2024
University of Potsdam
2024
Life Science Zurich
2022-2023
Abstract Hornworts comprise a bryophyte lineage that diverged from other extant land plants >400 million years ago and bears unique biological features, including distinct sporophyte architecture, cyanobacterial symbiosis pyrenoid-based carbon-concentrating mechanism (CCM). Here, we provide three high-quality genomes of Anthoceros hornworts. Phylogenomic analyses place hornworts as sister clade to liverworts plus mosses with high support. The lack repeat-dense centromeres well...
Summary Hornworts are crucial to understand the phylogeny of early land plants. The emergence ‘reverse’ U‐to‐C RNA editing accompanying widespread C‐to‐U in plant chloroplasts and mitochondria may be a molecular synapomorphy hornwort–tracheophyte clade. is well understood after identification many factors models like Arabidopsis thaliana Physcomitrella patens , but there no model yet investigate editing. hornwort Anthoceros agrestis now emerging as such system. We report on assembly analyses...
Understanding the molecular basis of morphological shifts is a fundamental question evolutionary biology. New morphologies may arise through birth/death genes (gene gain/loss) or by reutilizing existing gene sets. Yet, relative contribution these two processes to radical still poorly understood. Here we use model system mosses, Funaria hygrometrica and Physcomitrium (Physcomitrella) patens, investigate mechanisms underlying contrasting sporophyte architectures. We used comparative analysis...
Marchantia polymorpha has recently become a prime model for cellular, evo-devo, synthetic biological, and evolutionary investigations. We present pseudomolecule-scale assembly of the M. genome, making comparative genome structure analysis classical genetic mapping approaches feasible. anchored 88% draft to high-density linkage map resulting in eight pseudomolecules. found that overall is some respects different from moss Physcomitrella patens. Specifically, collinearity between two bryophyte...
A detailed protocol for the protoplast transformation of hornwort tissue is not yet available, limiting molecular biological investigations these plants and comparative analyses with other bryophytes, which display a gametophyte-dominant life cycle are critical to understanding evolution key land plant traits.We describe isolate transiently transform protoplasts model Anthoceros agrestis. The digestion liquid cultures Driselase yields high number viable suitable polyethylene glycol...
Abstract Mutualistic plant-microbe symbiotic interactions are thought to have evolved from a loose association between host plants and microbes when nutrients limited. Therefore, the molecular network enabling intimate mutualistic symbioses may nutrient starvation response shared by all land plants. While link status interaction is well-established, it remains poorly understood in some systems. This especially true for associations cyanobacteria. To test conservation of across as well...
Abstract High-dimensional cytometry (HDC) is a powerful technology for studying single-cell phenotypes in complex biological systems. Although technological developments and affordability have made HDC broadly available recent years, advances were not coupled with an adequate development of analytical methods that can take full advantage the data generated. While several platforms bioinformatics tools become analysis data, these are either web-hosted limited scalability or designed expert...
CD4 + T cells play a central role in the adaptive immune response through their capacity to activate, support and control other cells. Although these have become focus of intense research, comprehensive understanding underlying regulatory networks that orchestrate cell function activation is still incomplete. Here, we analyzed large transcriptomic dataset consisting 48 different human conditions. By performing reverse network engineering, identified six common denominators functionality...
Effective communication across fields and disciplines relies on well-defined terminology. Standardized use of accurate definitions has been advocated by scientists various (Tipton et al., 2019; PySek, 1995; Dubrovsky, 2022; Rillig, 2023; Rabin Brownson, 2017). Divergent interpretations or the application differing terminology can negatively impact interdisciplinary exchange, leading to missed information, hampered methodology transfer, ultimately impeding progress (Sapp, 2010; Tipton 2019)....