- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Electrospun Nanofibers in Biomedical Applications
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Acute Ischemic Stroke Management
- Electromagnetic Fields and Biological Effects
- Restraint-Related Deaths
John Cochran VA Medical Center
2023
Lifespan
2023
Brown University
2017-2020
Rhode Island Hospital
2020
Cornell University
2014-2015
Case Western Reserve University
2011-2014
MetroHealth Medical Center
2011
MetroHealth
2010
Idiopathic left ventricular arrhythmias (VAs) and those caused by structural heart disease can originate from the papillary muscles, fascicles, mitral annulus. Differentiation of these be challenging because they present with a right bundle branch block morphology electrocardiography. We sought to identify clinical, electrocardiographic, electrophysiological features that distinguish VAs in patients without disease.Patients undergoing catheter ablation for muscle, fascicular, or annular were...
IntroductionThe magnet-activated switch in implanted cardiac devices, including cardioverter-defibrillators and permanent pacemakers (PPM), is susceptible to interference from consumer devices with built-in magnets. For example, a recent case report showed that patient's cardioverter-defibrillator (ICD) magnet mode became activated owing interaction his e-cigarette.1Shea J.B. Aguilar M. Sauer W. Tedrow U. Unintentional reversion of an defibrillator by electronic cigarette.HeartRhythm Case...
Mesenchymal stem cells (MSCs) have been shown to improve cardiac electrophysiology when administered in the setting of acute myocardial infarction. However, electrophysiological phenotype MSCs situ is not clear. We hypothesize that delivered intramyocardially cryoinjured myocardium can engraft, but will actively generate, action potentials. Cryoinjury-induced scar was created on left ventricular epicardial surface adult rat hearts. Within 30 min, hearts were injected with saline (sham, n =...
Background: Recent studies have shown that outpatient cardiac monitoring for 30 days or longer increases detection rate of paroxysmal atrial fibrillation (AF) after Embolic Stroke Unknown Source (ESUS). For patients with AF detected on monitoring, anticoagulation can be initiated to reduce risk recurrent stroke. In this study, we aim compare characteristics between who received and those did not further elucidate trends in the use prolonged following ESUS. Methods: We analyzed a...
Multiple techniques have been developed in addition to pulmonary vein isolation (PVI) improve the outcomes of catheter ablation patients with persistent atrial fibrillation (AF). We sought evaluate long-term efficacy alternative used our laboratory for treatment AF, including spatiotemporal dispersion (SD) and low-voltage (LVI). Consecutive AF who underwent withthe studied between July 2016 December 2019 were included study.PVI alone was compared PVI plus SD LVI terms freedom from...
Background: Occult paroxysmal atrial fibrillation (AF) is detected in up to 30% of patients with Embolic Stroke Unknown Source (ESUS). We aim identify predictors AF on outpatient cardiac monitoring ESUS. Methods: included ischemic stroke ESUS subtype between January 1 st , 2013 and December 31 1st, 2016 who underwent an inpatient diagnostic evaluation, including 24 hour telemetry, followed by 30-day monitors and/or implantable monitor (ICM). Patients were divided into two groups based...
Background: Biomarkers to predict anticoagulation failure in patients with atrial fibrillation (AF) may help identify high-risk AF for further study. We hypothesize that left enlargement (LAE) is more prevalent admitted ischemic stroke who are therapeutic, as opposed non-therapeutic (NT), on anticoagulation. Methods: included consecutive a diagnosis of between April 1 st , 2015 and December 31 2016. Patients were divided into two groups based whether they therapeutic (warfarin international...
Background: The left atrial appendage (LAA) is the main source of thrombus in fibrillation (AF), and there an association between non-chicken wing (NCW) LAA morphology stroke. We hypothesized that prevalence would be higher among patients with cardioembolic (CE) stroke embolic undetermined (ESUS) than those non-cardioembolic (NCS). Methods: This multi-center retrospective study included consecutive ischemic from three comprehensive centers who previously underwent a qualifying chest CT....
Background: Outpatient cardiac monitoring for 30 days or longer increases detection rates of paroxysmal atrial fibrillation (AF) after cryptogenic stroke, but the ideal duration remains unclear. Two commonly used methods prolonged outpatient are 30-day continuous telemetry and insertable monitors (ICM). We aim to compare AF recurrent stroke between patients with Embolic Stroke Unknown Source (ESUS) monitored approximately (short term) vs. beyond ICM (long term). Methods: analyzed a single...
Background and Purpose: Previously we proposed a simple classification system of the left atrial appendage (LAA) morphology, with low risk (LAA-L) defined as one lobe an acute angle bend arising from proximal or middle portion high (LAA-H) all other morphologies. We aim to determine association between LAA morphology (using both systems), flow velocity, stroke rates. Methods: analyzed consecutive patients fibrillation (AF) selected for ablation who underwent cardiac CT angiography...
Objective: Clinical predictors of ischemic stroke in the setting atrial fibrillation (AF) have been identified, but there is limited data on context abnormal flow originating from left appendage. We hypothesize that reduced LAA velocity associated with cerebrovascular events patients AF. Methods: investigated consecutive AF evaluated for ablation. Peak velocities at orifice appendage (LAA) were obtained by transeosphageal echocardiography (TEE) studies, and elevated defined as greater than...
Monday, April 27April 14, 2020Free AccessMeasurement of Left Atrial Appendage Flow Velocity to Enhance Risk Assessment for Stroke in Fibrillation Patients (446)Eric Zhou, Andrew Chang, Nikhil Panda, Antony Chu, Karen Furie, Michael Atalay, Christopher Song, and Shadi YaghiAuthors Info & AffiliationsApril 2020 issue94 (15_supplement)https://doi.org/10.1212/WNL.94.15_supplement.446 Letters the Editor