A5008010244- Chronic Lymphocytic Leukemia Research
- Rheumatoid Arthritis Research and Therapies
- Renal Transplantation Outcomes and Treatments
- Acute Lymphoblastic Leukemia research
- Hematopoietic Stem Cell Transplantation
- Systemic Lupus Erythematosus Research
- Health Systems, Economic Evaluations, Quality of Life
- Drug Transport and Resistance Mechanisms
- Glutathione Transferases and Polymorphisms
- Pharmaceutical Economics and Policy
- Chemotherapy-induced organ toxicity mitigation
- Health and Wellbeing Research
- Statistical Methods in Clinical Trials
- Workplace Health and Well-being
- Diverse Approaches in Healthcare and Education Studies
- Tuberculosis Research and Epidemiology
- Pharmacological Effects and Toxicity Studies
- Renal cell carcinoma treatment
- Technology and Data Analysis
- Patient Satisfaction in Healthcare
- Thyroid and Parathyroid Surgery
- Meta-analysis and systematic reviews
- Occupational Health and Safety Research
- Nutrition, Health and Food Behavior
- Pregnancy and Medication Impact
CHA University
2022-2024
Seoul National University
2000-2023
Duksung Women's University
2023
Korea University
2022
Korea University Medical Center
2022
Seoul St. Mary's Hospital
2021
Catholic University of Korea
2021
New Generation University College
2021
Catholic University of Daegu
2021
Kangwon National University
2021
Clinical trial globalization is a major trend for industry-sponsored clinical trials. There has been shift in sites towards emerging regions of Eastern Europe, Latin America, Asia, the Middle East, and Africa. Our study objectives were to evaluate current characteristics trials find out associated multiple factors which could explain its implications 2011–2013. The data elements "phase," "recruitment status," "type sponsor," "age groups," "design trial" from 30 countries extracted...
A single-center retrospective observational case series was conducted. This enrolled patients who showed ophthalmic manifestations within one week after COVID-19 vaccination at Korea University Guro Hospital in Seoul, Korea, from May 2021 to January 2022. The medical records of complained ocular symptoms and adverse events were reviewed. Seventeen eyes 16 with a mean age 63.8 (range 33-83) years included the series, all developed 1-7 days following inoculation. Retinal vein occlusion nine...
Aim: A population pharmacokinetic (PPK) analysis was conducted to describe the influence of GSTA1 polymorphisms on intravenous busulfan in adults undergoing allogeneic hematopoietic stem cell transplantation. Patients & methods: PPK model developed from 36 patients by a one-compartment with first-order elimination. Results: The typical value clearance and volume distribution were 11.0 l/h 42.4 l, respectively. Clearance decreased 15% area under concentration-time curves (AUCs) increased...
Abstract Background Tumor necrosis factor (TNF) inhibitors use in patients with rheumatoid arthritis (RA) has raised safety concerns about cancer risk, but study results remain controversial. This largest nationwide to date compared risk TNF inhibitor users non-biologic disease-modifying anti-rheumatic drug (nbDMARD) Korean RA. Methods Data on all the eligible diagnosed RA between 2005 and 2016 were retrieved from National Health Information Database. The one-to-one matched consisted of...
BACKGROUND: Cyclosporine is often used to prevent allograft rejection in renal transplant recipients. However, cyclosporine has a narrow therapeutic window and large variability its pharmacokinetics. Individual characteristics genetic polymorphisms can cause the variation. Hence, it important determine cause(s) of variation To our knowledge, this first reported population pharmacokinetic study living donor recipients that considered polymorphism as covariate. OBJECTIVE: build model identify...
Background: Cyclosporine (CsA), which is used for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplant (allo-HSCT), has a narrow therapeutic range and large interindividual intraindividual pharmacokinetic variability. Nevertheless, population (PopPK) studies of CsA allo-HSCT are scarce. Objective: The goal our study was to build PopPK model consideration demographic, clinical, genetic polymorphisms data. Methods: A total 34 adult patients who received were...
As South Korea remains technically at war with the North, higher smoking prevalence in military might adversely affect Korea's power and contribute to lifetime men mandatory service. This study was identify priorities among anti-smoking strategies improve existing cessation programs for Korean military.The analytic hierarchy process model a goal, decision criteria, sub-criteria as well candidate strategies, developed following literature search expert group discussion. A survey pairwise...
Gene Delivery to the Rat Liver Using Cationic Lipid Emulsion/DNA Complex: Comparison between Intra-arterial, Intraportal and Intravenous AdministrationObjective: To compare efficiency of intra-arterial, intraportal, intravenous administration cationic lipid emulsion/DNA complex, as used for gene transfer rat liver.Materials Methods: DNA-carrier complex in-vivo experiment was prepared by mixing DNA a emulsion.According route (intra-arterial, or intravenous), animals were assigned one three...
Tumor necrosis factor inhibitors (TNFi) are proposed as a risk for nontuberculous mycobacteria (NTM) infection. Limited research investigates NTM infection in rheumatoid arthritis (RA) patients treated with TNFi compared to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), considering other concurrent or prior non-TNFi drugs. We aimed evaluate the associated using real-world database. Patients RA csDMARDs between 2005 and 2016 were identified utilizing Korean National...
Tumor necrosis factor-alpha (TNF-alpha) inhibitors are used as a treatment in various immune-mediated inflammatory diseases (IMIDs). Tuberculosis (TB) risk is reported several meta-analyses patients treated with TNF-alpha inhibitors. The purpose of this study to collect, review, and evaluate the TB according IMIDs indications between soluble-receptor inhibitor monoclonal-antibody
To construct a database of published clinical drug trials suitable for use 1) as research tool in accessing trial information and 2) evidence-based decision-making by regulatory professionals, investigators, medical practitioners.Comprehensive obtained from search design elements results peer reviewed journals using PubMed (http://www.ncbi.nlm.ih.gov/pubmed).The methodology to develop structured was devised panel composed experts medical, pharmaceutical, technology, members Ministry Food...
Background and Objectives This study aimed to identify a reliable preoperative predictive factor for the development of thyroid cancer in patients with atypia undetermined significance (AUS) identified by fine needle aspiration biopsy (FNAB). Subjects Method was retrospective cohort study. Two hundred ninety-nine diagnosed AUS FNAB who underwent curative surgery at our institution between September 2005 February 2014 were analyzed. Clinical, radiological molecular features investigated as...
(1) Background: Onsite clinics are increasingly common features of corporate health promotion programs. These allow employers to offer convenient care employees at their workplaces, which can lead reduced healthcare expenditure and improved productivity. The objective this study was build basic data by qualitatively exploring employees’ experiences perspectives on onsite in a semiconductor company, as one part the project examine improve management system large company Korea. (2) Methods:...
Choi, Bo Yoon MD; Kim, Seong-Woo MD, PhD; Yun, Cheolmin Oh, Jaeryung PhDEditor(s): Grewal, Dilraj S.; Valikodath, Nita; Feng, Henry L. Author Information
Purpose: Transcatheter arterial chemoembolization (TACE) is a common therapy for unresectable HCC, but it carries 5–16% risk of serious complications. TACI without embolization may have similar efficacy and fewer side effects, few studies examined outcomes TACI. Methods: We performed retrospective study 295 consecutive cases in 150 patients 1/99-9/02 at U.S hospital. All received mixture cisplatin, doxorubicin lipiodol were observed overnight. They evaluated clinically 2 weeks,...
(1) Background: This study aimed to analyze the risk of chronic diseases including hypertension, diabetes, and dyslipidemia in workers a semiconductor manufacturing company factors associated with their participation workplace health promotion (WHP) programs. (2) Methods: Subjects were liquid crystal display South Korea who had undergone regular checkups. Data from checkups WHP interventions analyzed. Health was classified based on diagnosed disease, in-house classification criteria, pooled...
이용자 관점에서 도서관 서비스에 대한 품질 평가는 시간의 흐름과 정보기술과 같은 환경에 따라 변화한다. 따라서 도서관은 서비스 품질과 만족도를 지속적으로 측정하여 새로운 필요한 개선점을 도출할 필요가 있다. 본 연구의 목적은 국내외 대학도서관을 대상으로 LibQUAL+ 평가 결과의 변화와 경향을 분석하고 개선 방향을 규명하고자 하였다. 이를 위해 대학도서관 각각 1개관을 선정하였다. 캐나다 맥길대학교 6년간 누적된 LibQUAL+결과를 하였으며, 국내 A대학은 2012년 결과와 연구에서 수행한 2015년 결과를 분석하였다. 분석방법으로는 방사형 차트, 막대 그래프를 이용하여 22개 항목, 3개 차원에 이상 기대치, 실제 인식치, 최소 기대치와 적정성 갭, 우수성 갭의 변화를 비교․분석하였다. 분석 결과는 연도별, 학부생과 대학원생의 인식수준의 변화 및 기대수준에 있어 현저한 차이가 있음을 보여주었다. 특히, A대학의 분석결과는 이용자들의 전반적인 도서관의 기대수준이...
Purpose: To correlate the degree of renal cortical enhancement, objectively evaluated by means spiral CT, with serum level creatinine, and to determine extent which this enhancement may be used detect parenchymal disease. Materials Methods: Eighty patients [M:F=50:30; age=25 -90 (mean, 53) years] available creatinine who underwent CT between September October 1999 were included in study. In fifty findings suggested hepatic or biliary diseases such as hepatoma, cancer, stone, while thirty,...