A5059750308- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Intraocular Surgery and Lenses
- Neuroscience and Neural Engineering
- Ocular Diseases and Behçet’s Syndrome
- Silicone and Siloxane Chemistry
- Polymer Nanocomposites and Properties
- Ophthalmology and Visual Impairment Studies
- Chemokine receptors and signaling
- biodegradable polymer synthesis and properties
- Polymer crystallization and properties
- Photoreceptor and optogenetics research
- Advanced Memory and Neural Computing
- Multiple Myeloma Research and Treatments
- Optical Coherence Tomography Applications
- Vascular Malformations Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- Immune Response and Inflammation
- Synthesis and properties of polymers
- Metal and Thin Film Mechanics
- Cytokine Signaling Pathways and Interactions
Pohang Iron and Steel (South Korea)
2017-2024
Korea University
2015-2024
Korea University Medical Center
2009-2023
Onnuri Smile Eye Clinic
2022-2023
Dong-A University
2023
Data Management (Italy)
2022
Ministry of Science
2022
Armed Forces Capital Hospital
2022
Wonkwang University
2020
National Research Foundation of Korea
2020
In Brief Purpose: To compare choroidal thicknesses among eyes with early age-related maculopathy (ARM), neovascular macular degeneration, polypoidal vasculopathy, and central serous chorioretinopathy. Methods: Patients (37 eyes), degeneration (24 vasculopathy (12 chorioretinopathy (31 eyes) underwent spectral-domain optical coherence tomography evaluations using a choroid scanning protocol. A horizontal linear section comprising 50 averaged scans was obtained of each macula. The thickness...
Epidermal growth factor receptor (EGFR) is overexpressed in a subset of human epidermal 2 (HER2)-positive breast cancers, and coexpression HER2 EGFR has been reported to be associated with poor clinical outcome. Moreover, interaction between suggested possible basis for trastuzumab resistance. We analysed the significance overexpression gene copy number alterations 242 HER2-positive primary cancers. In addition, we examined correlations overexpression, response outcome 447 primary, 112...
Purpose: To determine the relationship between aqueous concentrations of inflammatory and angiogenic factors severity diabetic retinopathy macular edema.Methods: Aqueous samples were obtained from 50 eyes patients 28 nondiabetic subjects. The levels factors, including IL-1β, TNF-α, MCP-1, IP-10, IL-8, IL-6, VEGF measured with multiplex bead array assays. cytokines investigated according to edema by optical coherence tomography.Results: higher in than MCP-1 IP-10 elevated severe NPDR PDR...
Although approximately 20 common genetic susceptibility loci have been identified for breast cancer risk through genome-wide association studies (GWASs), variants reported to date explain only a small fraction of heritability this cancer. We conducted four-stage GWAS including 17 153 cases and 16 943 controls among East-Asian women search new factors After analyzing 684 457 SNPs in 2062 2066 (Stage I), we selected replication 5969 Chinese (4146 1823 controls) the top 49 that had neither...
Abstract For the application of single‐layer food packaging films with improved barrier properties, an attempt was made to prepare ethylene‐vinyl alcohol (EVOH) copolymer‐based nanocomposite by incorporation organically modified montmorillonite nanoclays via a two‐step mixing process and solvent cast method. The highly intercalated tactoids coexisted exfoliated clay nanosheets, extent intercalation exfoliation depended significantly on level loadings, which were confirmed from both XRD...
Abstract Background and Aim Dietary factors are closely associated with the risk of non‐alcoholic fatty liver disease ( NAFLD ). A sian W estern diets differ in energy‐nutrient composition, fatty‐acid main nutritional sources; therefore, implications would be limited if Western‐oriented study results were applied to Asian patients. We aimed identify nutrient food group intakes a typical diet assess their effects on risk. Methods I n total, 348 subjects recruited from 5 participating...
To investigate systemic factors associated with central serous chorioretinopathy (CSC).We retrospectively reviewed the medical records of 113 Korean patients who were diagnosed CSC and underwent history taking a specialized questionnaire for CSC. They matched age gender at ratio 1 : 3 to 339 normal controls. Normal controls consecutively selected from database Health Promotion Center. General characteristics histories compared between two groups. The statistical analyses used included...
Prospective findings have not been consistent for folate, vitamin B(12) and homocysteine concentrations as predictors of dementia. This study aimed to investigate both baseline changes in these predictors/correlates incident dementia.Of 625 elderly patients without dementia at baseline, 518 (83%) were followed over a 2.4 year period clinically assessed Alzheimer's disease (AD). Serum measured the follow-up assessments. Covariates included age, sex, education, disability, depression, alcohol...
Abstract Background The fate of the portal vein (PV) after pancreatoduodenectomy, especially its long-term patency and associated complications, has received little attention. aim this study was to explore rate PV focusing on risk factors for stenosis/occlusion complications. Methods Serial CT images patients who underwent pancreatoduodenectomy periampullary cancer between January 2000 June 2012 in a single institution were evaluated stenosis or occlusion. Results A total 826 enrolled. 19·6...
This study aimed to determine the association between shift work and inflammatory markers, which are independent risk factors of cardiovascular diseases, in male manual workers at a display manufacturing company.This was conducted June 1 July 31, 2015 on 244 aged 20-39 years old company investigated age, marital status, education level, alcohol consumption habit, smoking regular exercise sleep duration, debt, insufficiency, past medical history, current experience, duration work, weekly...
Purpose: To investigate variations in chorioretinal vasculatures fellow eyes of patients with unilateral neovascular age-related macular degeneration (nAMD). Methods: We included consecutive nAMD from swept source optical coherence tomography (SS-OCT) angiography database. Vascular and nonvascular indices were determined based on SS-OCT images. Variation the vascular or index was compared between without early AMD. Results: In 146 eyes, 88 (60.3%) had AMD 58 (39.7%) a normal fundus. density...
Retinal prostheses have shown some clinical success in patients with retinitis pigmentosa and age-related macular degeneration. However, even after the implantation of a retinal prosthesis, patient's visual acuity is at best less than 20/420. Reduced may be explained by decrease signal-to-noise ratio due to spontaneous hyperactivity ganglion cells (RGCs) found degenerate retinas. Unfortunately, abnormal rewiring, commonly observed retinas, has rarely been considered for development...
Abstract The objective of this study was to investigate the relationship between suspended scattering particles in motion (SSPiM) optical coherence tomography angiography (OCTA) and treatment response diabetic macular edema (DME). We retrospectively reviewed medical records patients diagnosed with DME who had undergone intravitreal injection. density ratio (ODR) intraretinal cyst numbers hyperreflective foci from OCT images SSPiM OCTA were compared, their association analyzed. Forty-five...
<i>Purpose:</i> To report a case of complete regression choroidal metastasis secondary to non-small-cell lung cancer (NSCLC). <i>Methods:</i> Retrospective review female patient treated with intravitreal bevacizumab and oral erlotinib combination therapy for metastases NSCLC. Best corrected visual acuity (BCVA), fluorescein angiography (FA), optical coherence tomography (OCT), B-scan ultrasonography were compared during the 4-month treatment period....