Background: Although now an important aspect of medical education, teaching ethics presents challenges, including a perceived lack value or relevance by students and dearth effective methods for faculty. Team-based learning (TBL) was introduced into our course to respond these needs.Aims: We evaluated the impact TBL on student engagement satisfaction assessed educational achievements.Method: The education using consisted four 2 h sessions first-year Chonnam National University Medical...

Macrophage polarization plays an important role in tissue damage and repair. In this study, we show that Substance-P (SP) can directly induce M2 of inflammatory macrophages. SP induced the differentiation GM-CSF-differentiated pro-inflammatory macrophages into alternatively activated phagocytic like (M2SP) through direct activation PI3K/Akt/mTOR/S6kinase pathway induction Arginase-1, CD163, CD206, all which were nullified by pretreatment with neurokinin-1 receptor (NK-1R) antagonist RP67580...

The potential benefits or the tissue-damaging effects of inflammatory response after central nervous system injuries have long been disputed. Recent studies noted that substance P (SP), a neuropeptide, plays an important role in wound-healing process by recruiting bone marrow stem cells to injured tissue. In this study, we examined whether SP can enhance recovery from spinal cord injury (SCI) Sprague-Dawley rats through its known function cell mobilization and/or modulation inflammation. We...

A learning approach embeds the intention of student when starting a task and processes strategies used to carry out task. Student approaches have been categorized as deep, strategic, surface.To explore relationships among medical students' approaches, gender, performance on summative high-stakes clinical examination (CPX).We measured at beginning year four using Approaches Study Skills Inventory for Students compared results with CPX scores.Student scores in top two quartiles were...

MEnEtrier's disease (hypoproteinemic hypertrophic gastropathy) is a rare, acquired, premalignant disorder of the stomach.1–4 It characterized by giant folds that most often involve fundus, excess mucus secretion, decreased acid secretion (hypochlorhydria), and hypoproteinemia due to selective loss serum proteins across gastric mucosa.5,6 The cause Menetrier's unknown, although infection with cytomegalovirus (CMV) in children Helicobacter pylori have been implicated.7,8 Symptoms include...

Peer-assisted learning encourages students to participate more actively in the dissection process and promotes thoughtful dissection. We implemented peer-assisted 2012 compared its effects on students' self-assessments of their academic achievement with those faculty-led All subjects performed dissections after a lecture about upper-limb gross anatomy. Experimental group (n = 134) dissected cadaver while guided by peer tutors who had prepared for advance, control 71) introduction faculty via...

Purpose: The revised Clinical Skills Test (CST) of the Korean Medical Licensing Exam aims to provide a better assessment physicians’ clinical competence and ability interact with patients. This study examined impact CST on medical education curricula resources nationwide, while also identifying areas for improvement within CST.Methods: surveyed faculty responsible clerkships at 40 schools throughout Korea evaluate status changes in skills education, assessment, related CST. researchers...

Few clinical data are available on the relationship between genospecies and outcome of Acinetobacter bacteremia, results inconsistent. We performed this study to evaluate bacteremia.Clinical from 180 patients who had bacteremia 2003 2010 were reviewed retrospectively. The identified by rpoB gene sequence analysis. features outcomes 90 with A. baumannii compared those non-baumannii (60 nosocomialis, 17 species "close 13 TU", 11 pittii, two calcoaceticus).A. was associated intensive care...

Abstract Several groups have reported that TGFβ1 regulates cellular responses to γ-irradiation; however, the exact mechanism has not been fully elucidated. In current study, role of in γ-irradiation was investigated detail. The data indicate pretreatment decreased aftermath ionizing radiation (IR)-induced DNA damage a SMAD-dependent manner. To determine underlying for these effects, extent IR-induced repair activity presence or absence examined. Studies reveal upregulated ligase IV (Lig4),...

Previously, we have reported that substance P (SP) enhanced functional recovery from spinal cord injury (SCI) possibly by the anti-inflammatory modulation associated with induction of M2-type macrophages at injured lesion. In this study, explored cytokine expression profiles and apoptotic cell death in lesion site SCI after an immediate intravenous injection SP. SP increased levels interleukin-4 (IL-4), IL-6, IL-10 day 1 approximately 2-, 9-, 10-folds when compared control SCI, respectively....

Mechanical stimulation is a known modulator of survival and proliferation for many cells, including endothelial smooth muscle bone marrow-derived mesenchymal stem cells. In this study, we found that mechanical strain prevents apoptosis increases the adhesive ability dermal fibroblasts in vitro thus confers advantage vivo after transplantation into full-thickness wound diabetic mice. Cyclic stretch at frequency 0.5 Hz maximum elongation 20% stimulates cellular mediated by activation...

Abstract Isoliquiritigenin (ISL), a flavonoid found in licorice, shallot, and bean sprouts, has been identified as potent anti‐tumor promoting agent. We previously demonstrated that ISL reduces cell proliferation induces apoptosis DU145 human prostate cancer cells MAT‐LyLu (MLL) rat cells. Overexpression of members the ErbB receptor family is frequently observed event several cancers, receptors currently constitute primary targets anticancer strategies. In order to elucidate mechanisms...

Scaffolds are one of the three most important elements constituting basic concept regenerative medicine, and included in core technology medicine along with stem cells tissue engineering. Stem very because they directly responsible for treatment disease damaged tissue, but regards to products that use exclusively, there is a technical limitation limited survival rate engraftment transplanted cell, rather than recovering fundamentally, limit more just another using cells. A scaffold natural...

As a way of understanding the image needs users, researchers in retrieval field have investigated contextual factors affecting and search behaviours. In terms both general users’ groups non-domain-specific collections on web, purpose this study is to investigate how are interwoven with intended uses which varying degrees use purposes. Thus, image-seeking questions posted social Q&A service were analysed for their content. The findings indicate that as sources objects found more...

This study aims to identify the way researchers collaborate with other in course of scientific research life cycle and provide information designers e ‐ S cience R esearch implementations. On basis in‐depth interviews on‐site observations 24 scientists a follow‐up focus group interview field bioscience/nanoscience technology K orea, we examined collaboration using framework cycle. We attempt explain major motivations, characteristics communication sharing, barriers associated scientists'...