A5101494585- Phytochemical compounds biological activities
- Phase Equilibria and Thermodynamics
- Land Use and Ecosystem Services
- Heat transfer and supercritical fluids
- Natural product bioactivities and synthesis
- Process Optimization and Integration
- Plant and animal studies
- Insect and Pesticide Research
- Insect Pest Control Strategies
- Conservation, Biodiversity, and Resource Management
- Plant chemical constituents analysis
- Embedded Systems Design Techniques
- Conferences and Exhibitions Management
- Sustainability and Climate Change Governance
- Distributed and Parallel Computing Systems
- Synthesis and Biological Evaluation
- Sesquiterpenes and Asteraceae Studies
- Traditional and Medicinal Uses of Annonaceae
- Food Chemistry and Fat Analysis
- Plant tissue culture and regeneration
- Trypanosoma species research and implications
- Berry genetics and cultivation research
- Growth Hormone and Insulin-like Growth Factors
- Chemotherapy-induced cardiotoxicity and mitigation
- Peripheral Nerve Disorders
Hospital de São João
2023
Universidade Nova de Lisboa
2005-2020
Universidade Federal de São Carlos
1996-2016
Hospital Universitário Oswaldo Cruz
2015
Rede de Química e Tecnologia
2005-2009
Comissão Executiva do Plano da Lavoura Cacaueira
2007
Universidad Nacional Autónoma de México
2007
Universidade de São Paulo
2002
Universidade Federal de São Paulo
1998
World Health Organization - Pakistan
1998
Ecosystem service (ES) spatial modelling is a key component of the integrated assessments designed to support policies and management practices aiming at environmental sustainability. ESTIMAP ("Ecosystem Service Mapping Tool") collection spatially explicit models, originally developed European scale. We based our analysis on 10 case studies, 3 ES models. Each study applied least one model local analyzed applications with respect to: adaptation process; "precision differential" which we...
The feasibility of in situextraction and transesterification spent coffee ground oil into fatty acid methyl esters with supercritical methanol has been investigated the temperature range 473–603 K, pressure 10.0–30.0 MPa. At 30.0 MPa 603 a (FAME) yield 84.9% was obtained. Carbon dioxide added to aim reducing operating pressure. It demonstrated that at reaction 573 10.0 CO2/MeOH molar ratio 0.11, FAME 93.4%
Main text The CCQM-K78.b key comparison was coordinated by the Bureau International des Poids et Mesures (BIPM) on behalf of CCQM Organic Analysis Working Group (OAWG) 'Comité Consultatif pour la Quantité de Matière' (CCQM), for National Measurement Institutes (NMIs) and Designated (DIs) providing measurement services in organic analysis under Mesures' (CIPM) Mutual Recognition Arrangement (MRA). This conducted as a 'Track A' within OAWG's 10-year strategic plan. goal to underpin...
A contabilidade tem se consolidado como um instrumento fundamental para a gestão de riscos nas organizações, desempenhando papel estratégico na identificação, avaliação e mitigação ameaças financeiras operacionais. Em cenário crescente complexidade econômica regulatória, torna-se essencial compreender práticas contábeis eficientes podem contribuir sustentabilidade empresarial. Este estudo teve objetivo analisar o impacto da riscos, investigando sua relação com governança corporativa,...
A contabilidade tributária desempenha um papel essencial na gestão empresarial, garantindo a conformidade fiscal e prevenindo penalidades decorrentes do descumprimento das normas tributárias. O estudo analisou como correta aplicação fiscais adoção de estratégias contábeis eficientes podem minimizar os riscos autuações otimizar carga empresas. pesquisa, baseada em revisão bibliográfica, demonstrou que escolha regime tributário adequado, o planejamento estruturado uso tecnologias são fatores...
A contabilidade digital surge como resposta às demandas da Quarta Revolução Industrial, incorporando tecnologias inteligência artificial, big data e sistemas em nuvem que remodelam profundamente a atuação do profissional contábil. Neste cenário de transformação, o presente estudo justifica-se pela necessidade compreender os impactos reais digitalização nos processos nas competências exigidas pelo mercado. O objetivo central pesquisa é analisar afeta desempenho contador, identificando...
Citrus biomass is a source of biobased products and presents extensive chemical diversity.Among the structural macromolecules, lignins have been used in resins, bioplastics, nanoencapsulation.Brazil has large lignins, which are orange trees removed from groves that need to be renewed.However, knowledge about these limited little explored.Thus, this work aimed evaluate sinensis provide information on interesting use as macromolecules.The were isolated trunk, central secondary roots tree by...
Abstract Crude extracts of Rutales species were tested in vitro against the trypomastigote form Trypanosoma cruzi at 4 mg/mL, and 20% them showed significant activity (80%). Their inhibitory glycolytic enzyme GAPDH from T. has also been evaluated concentrations 100 200 mg/mL. Additionally, 13 purified coumarins assayed cruzi-GAPDH. Chalepin was most active substance with IC50 = 64 mM. The 3D structure complex chalepin-enzyme elucidated by X-ray crystallography, revealing architecture...
This present investigation deals with the development and optimization of polymeric nanoparticle systems loaded 3,5,3'-triiodothyroacetic acid (Triac). A 2(11-6) fractional factorial design another 2(2) were used to study contrasts on particle size distribution, morphology, surface charge, drug content, entrapment efficiency, in vitro release profiles. The independent variables concentration Triac, type quantity both polymer oil, Span™ 60 Tween® 80, volume solvent water, velocity magnetic...
A phytochemical investigation of the stems South Brazilian endemic species Raulinoa echinata has led to isolation two new methoxylated protolimonoid epimers (1 and 2) together with known melianone melianodiol. The leaves afforded three glabretal-type triterpene derivatives esterified by N-methylanthranilic acid (3−5). Compounds 1 2 displayed weak inhibitory activity when assayed in vitro against trypomastigote forms Trypanosoma cruzi. 1−5 were inactive a brine shrimp (Artemia salina) lethality test.
Mapping of ecosystem services (ES) is a powerful tool for communication and knowledge sharing about the implications management practices human wellbeing. This research aimed to show usefulness ES mapping decision-making by combining modelling supply with demand in participatory process engagement relevant stakeholders. We used ESTIMAP-pollination model map wild bee abundance pollination Sudoeste Alentejano Costa Vicentina Natural Park (PNSACV) Portugal. The was modified adding behavioural...
Four natural products were isolated from the fungus Botryosphaeria rhodina, and their effects on photosynthesis tested. Only lasiodiplodin (1) inhibited ATP synthesis electron flow water to methylviologen; therefore, it acts as a Hill reaction inhibitor in freshly lysed spinach thylakoids. Photosystem I II partial reactions well ATPase measured presence of 1. Three new different sites 1 interaction inhibition found: one at CF1, second water-splitting enzyme, third electron-transfer path...
Because Full Waveform Inversion (FWI) works with a massive amount of data, its execution requires much time and computational resources, being restricted to large-scale computer systems such as supercomputers. Techniques FWI adapt well parallel computing can be parallelized in shared memory using the application programming interface (API) OpenMP. The management tasks performed through loop schedulers contained dynamic scheduler stands out for distributing predefined fixed-size chunk sizes...
Six mexicanolide limonoids isolated from the dichloromethane extract of fruits Cipadessa fruticosa Blume (Meliaceae) were evaluated against Spodoptera frugiperda (J. E. Smith). Gedunin was used as a positive control. When incorporated into an artificial diet neonates at 50.0 mg kg(-1), febrifugin A showed 73.3% mortality. All compounds moderate insecticidal activity, except for ruageanin A, when compared with Febrifugin also growth inhibition and antifeedant activities (at 100.0 kg(-1)). The...
The most complete dynamic model to date of a supercritical fluid extraction (SFE) plant is presented and experimentally validated. SFE flowsheet modularly organized into set detailed sub-models the main unit operations, including packed column, solvent heat exchanger, product recovery regeneration make-up. modules are interconnected through appropriate boundary conditions that establish continuity mass, momentum, energy. present significantly improves our previous modeling efforts by, among...
Previous investigations of H. oreadica reported the presence a wide spectrum complex limonoids and dihydrocinnamic acids. Our interest in Rutaceae motivated reinvestigation oreadica, brasiliana superba searching for other secondary metabolites present substantial amounts taxonomic analysis. In continuation investigation three new have now been isolated 9α-hydroxyhortiolide A, 11β-hydroxyhortiolide C 1(S*)-acetoxy-7(R*)-hydroxy-7-deoxoinchangin. All compounds from Hortia species reinforce its...
Indiscriminate use of synthetic pesticides can be hazardous to both humans and the environment, but natural products as a source bio-based products, such Melia azedarach extracts, is an interesting approach overcome these hazards. Unfortunately, limonoids found in M. with desired insecticidal properties (e.g. azadirachtin) may also present toxic mammals. The goal this report was develop fast reliable MS-based experiment characterize meliatoxins crude extracts azedarach, order provide...
SummaryLaboratory bioassays were conducted to evaluate toxicity of methanolic and dichloromethane extracts obtained from Stryphnodendron adstringens Apis mellifera Scaptotrigona postica workers. The incorporated into the diet bees for evaluation mortality rates. ingestion made with three concentrations (0.002mg/g, 0.005mg/g 0.01mg/g) each bee species. workers kept in cages, twenty per cage concentration tested. All had sixty cages that where maintained a biological oxygen demand incubator...
Molecular phylogenetic studies separated and united a group of genera that constituted the Spathelia-Ptaeroxylon clade, in which Dictyoloma Sohnreyia have been included.Our taxonomic interest vandellianum excelsa stimulated an investigation both species searching for limonoids.Leaves from D. afforded new limonoid 1,2-dihydro-1α-hydroxy-8,30-epoxy-cneorin R, heartwood yielded rearranged dictyolomin.Leaves S. protolimonoid...