A5100677611- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Acute Ischemic Stroke Management
- Advanced MRI Techniques and Applications
- Ginkgo biloba and Cashew Applications
- Neurological Disease Mechanisms and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Cardiac Imaging and Diagnostics
- Barrier Structure and Function Studies
- MRI in cancer diagnosis
- Intracranial Aneurysms: Treatment and Complications
- Renal and Vascular Pathologies
- Drug Transport and Resistance Mechanisms
- Parkinson's Disease Mechanisms and Treatments
- Adrenal and Paraganglionic Tumors
- Calpain Protease Function and Regulation
- Spinal Dysraphism and Malformations
- Case Reports on Hematomas
- Lymphoma Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Diagnosis and Treatment
- Machine Learning in Materials Science
- Biological Stains and Phytochemicals
- Gastrointestinal Tumor Research and Treatment
Fudan University
2014-2023
Zhongshan Hospital of Xiamen University
2023
Zhongshan Hospital
2012-2022
Sun Yat-sen University
2014-2022
The First Affiliated Hospital, Sun Yat-sen University
2014-2022
Union Hospital
2021
Huazhong University of Science and Technology
2013-2021
University of Macau
2020
Shanghai Medical College of Fudan University
2012-2017
China Pharmaceutical University
2009-2011
Purpose To compare Multicontrast ATherosclerosis Characterization (MATCH) with conventional multicontrast magnetic resonance imaging (MRI) in the characterization and quantification of carotid plaque components. Materials Methods Fifty‐three consecutive patients underwent 3.0T MRI including sequences MATCH, 13 them having endarterectomy for histology validation. The detection major components lipid‐rich necrotic core (LRNC), loose matrix (LM), intraplaque hemorrhage (IPH), calcification (CA)...
<h3>BACKGROUND AND PURPOSE:</h3> Dual-source CTA and black-blood MRA are recently developed techniques for evaluating carotid stenosis. The purpose of this study was to compare dual-source with conventional TOF in both detecting stenosis by using DSA as a reference standard demonstrating plaque morphology. <h3>MATERIALS METHODS:</h3> Thirty patients suspected artery underwent unenhanced CTA. Source images from MRAs were reconstructed MIP or curved planar reconstruction. degree measured,...
3D high-resolution vessel wall imaging is increasingly used for intracranial arterial diseases. This study compared the diagnostic performance of black-blood luminal angiography derived from with source images and TOF-MRA in detecting middle cerebral artery stenosis.Sixty-two patients suspected MCA atherosclerosis underwent TOF-MRA, imaging, CTA. Intracranial was created using minimum intensity projection. The degree length stenosis were measured on CTA as a reference standard.The image...
The relationship between plaque calcification and new ischemic brain lesions after carotid artery stenting (CAS) remains controversial. purpose of this study was to determine if the circumferential degree is associated with on diffusion-weighted imaging (DWI) CAS.A total 96 patients stenosis ≥50% who underwent CAS were enrolled in study. All preoperative computed tomography (CT), postoperative MRI. MRI sequences included T1WI, T2WI, T2-fluid-attenuated inversion recovery (FLAIR), DWI....
Background: The carotid blood flow following endarterectomy (CEA) is not fully understood. Computational fluid dynamics (CFD) a promising method to study flow. This investigate local hemodynamic characteristics after CEA via the use of unenhanced magnetic resonance angiography (MRA) and CFD. Methods: Eight arteries with atherosclerosis sixteen normal were included in this study. Time-of-flight (TOF) phase contrast (PC) MRA applied for measurement three-dimensional artery geometries velocity...
Coronary computed tomographic angiography is a robust non-invasive method to assess coronary artery disease (CAD) and analyze plaque stability, especially for the non-calcified plaques. The aim of this study was investigate differential characteristics between unstable plaques stable using multi-slice tomography (MSCT).Sixty patients with heart (37 31 plaques) were included. napkin ring thickness, napkin-ring sign, CT attenuation degree lumen stenosis retrospectively analyzed. diagnostic...
Objective This study was aimed to evaluate the accuracy of “True Fast Imaging with Steady-State Precession” (TrueFISP) MR angiography (MRA) for diagnosis renal arterial stenosis (RAS) in hypertensive patients. Methods Twenty-two patients underwent both TrueFISP MRA and contrast-enhanced (CE-MRA) on a 1.5-T imager. Volume main arteries, length maximal visible number visualized branches, stenotic grade, subjective quality were compared. Paired 2-tailed Student t test Wilcoxon signed rank...
Cerebral ischemia is one of the leading causes for death and severe disabilities in world. XQ-1H exerts neuroprotective effects under various neurotoxic conditions vitro. In vivo, it reduces brain damage after transient focal cerebral ischemia. The present study evaluated dose effectiveness therapeutic time window neuroprotection by behavioral histological measures rats subjected to permanent middle artery occlusion (pMCAO). Neurological deficits, TTC stain, water content, necrosis neuron...
Protein-tyrosine phosphatase 1B (PTP1B) has been considered as a promising target for treating insulin resistance. In searching naturally occurring PTB1B antagonists, two new pimarane diterpenoids, named 2α-hydroxy-7-oxo-pimara-8(9),15-diene (1) and 19-hydroxy-2α-acetoxy-7-oxo-pimara-8(9),15-diene (2), were isolated from the seeds of Caesalpinia minax. Their structures determined by extensive analysis NMR HR-ESIMS data, their absolute configurations electronic circular dichroism (ECD)...
Preoperative assessment of the integrity major thoracic vessels in central bronchogenic carcinoma is vital for tumor staging and treatment planning. Contrast-enhanced CT currently first choice modality this purpose clinical practice with limitations including exposure to ionizing radiation use iodinated contrast material. MRI has been increasingly employed lung cancer. More recently, unenhanced magnetic resonance angiography (MRA) which totally non-invasive contrast-free reported able show...