A5100644959- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Respiratory viral infections research
- Genetic Mapping and Diversity in Plants and Animals
- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Genetics and Plant Breeding
- Hippo pathway signaling and YAP/TAZ
- Cardiac Imaging and Diagnostics
- Acute Myeloid Leukemia Research
- Cancer Cells and Metastasis
- COVID-19 Clinical Research Studies
- Traditional Chinese Medicine Studies
- SARS-CoV-2 and COVID-19 Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pharmacological Receptor Mechanisms and Effects
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Gastric Cancer Management and Outcomes
- Emergency and Acute Care Studies
- Cardiovascular Disease and Adiposity
- Circular RNAs in diseases
- Nosocomial Infections in ICU
- Antifungal resistance and susceptibility
- Acupuncture Treatment Research Studies
Jilin Academy of Agricultural Sciences
2018-2025
Shandong Provincial Hospital
2020-2024
Shandong First Medical University
2020-2024
Hunan University
2024
University of Hong Kong
2017-2024
University of Fort Lauderdale
2024
Shengli Oilfield Central Hospital
2013-2024
Chinese University of Hong Kong
2024
University of Minnesota
2024
Shandong University
2024
With persistent inconsistencies in colorectal cancer (CRC) miRNAs expression data, it is crucial to shift toward inclusion of a "pre-laboratory" integrated analysis expedite effective precision medicine and translational research. Aberrant hsa-miRNA-195 (miR-195) which distinguished as clinically noteworthy miRNA has previously been observed multiple cancers, yet its role CRC remains unclear. In this study, we performed an seven datasets. The miR-195 was validated Cancer Genome Atlas (TCGA)...
Anoikis resistance is an essential prerequisite for tumor metastasis, but the underlying molecular mechanisms remain unknown. Herein, we report that oncoprotein hepatitis B X-interacting protein (HBXIP) prominently upregulated in breast cancer cells following ECM detachment. Altering HBXIP expression can impair anchorage-independent growth ability of cells. Mechanistically, HBXIP, which binds to Kelch-like ECH-associated 1 (Keap1) activate nuclear factor E2-related 2 (Nrf2), contains a...
Multi-drug resistance (MDR) has been a cause of concern for tuberculosis (TB) control in both developed and developing countries. This study described the characteristics risk factors associated with MDR-TB among 287 cases 291 controls Henan province, China. A hospital-based case-control was conducted between June 2012 December 2013. The subjects were selected using multistage probability sampling. Multivariate conditional logistic regression models used to determine MDR-TB. following...
Objectives To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China. Design This was a multicentre, retrospective, observational study. Setting 13 teaching hospitals northern, central southern China from 1 January 2014 to 31 December Participants Information on aged ≥14 years radiographically confirmed illness onset community collected using standard case report forms. Primary secondary outcome measures Resource use for...
Background Maize ( Zea mays L.) is one of the main agricultural crops with largest yield and acreage worldwide. at germination sprouting stages are highly sensitive to low-temperatures, especially in high-latitude high-altitude regions. Low-temperature damage early spring presents a major meteorological disaster maize, severely affecting plant growth maize yield. Therefore, mining genes tolerant low temperatures crucial. We aimed analyze differential gene expression construct co-expression...
Limited information exists on the clinical characteristics predictive of mortality in patients aged ≥65 years many countries. The impact adherence to current antimicrobial guidelines hospitalized elderly with community-acquired pneumonia (CAP) has never been assessed.
Circulating tumor cells (CTCs) have been regarded as a promising biomarker for colorectal cancer (CRC); however, the prognostic value of post-operative (op) CTCs is still unclear. This study aimed to compare recurrence prediction pre- and post-op in CRC patients treated with curative resection.Consecutive resection from January 2014 March 2015 were identified. 2.5 mL peripheral blood enumerated an ISETdevice-CTCBIOPSY® before after surgery. Based on status CTCs, included grouped into four...
Background:The preoperative controlling nutritional status (CONUT) score and circulating tumour cell (CTC) are associated with poor prognosis of colorectal cancer (CRC).The aim the present study is to determine whether combination CONUT CTC (CONUT-CTC) could better predict CRC patients treated curative resection.Methods: Preoperative was retrospectively calculated in 160 who underwent resection at Zhongnan Hospital Wuhan University from 2015 2017.Preoperative counts were enumerated 5 ml...
Glasgow prognostic score (GPS) is widely known as a systemic inflammatory-based marker. The relationship between pretreatment GPS and gastric cancer (GC) survival clinicopathological features remains controversial. aim of the study was to conduct meta-analysis published studies evaluate association in GC patients.We searched PubMed, Embase, MEDLINE, BioMed databases for relevant studies. Combined analyses were used assess overall survival, disease-free parameters by Stata Version 12.0.A...
With the increase in incidence of diabetes, health care feet diabetic patients becomes particularly important. Herein, leather fiber (LF) was utilized with waterborne polyhexamethylene guanidine-embedded polyurethane (PPU) to prepare network-interpenetrating LF/PPU composites as potential foot material via a facile "paper-making" pathway. Due coating PPU on LF, release chromium sweat is significantly reduced. The fibrous structure endows temporary hydrophobicity, air permeability, and...
Summary: Purpose: We analyzed the occurrence and clinical features of myoclonus in patients with end‐stage renal disease (ESRD) who were treated gabapentin (GBP). Methods: reviewed medical records ESRD GBP hospitalized during an 18‐month period details such as type myoclonus, doses GBP, electroencephalographic (EEG) findings, relation symptoms to exposure dosage. Results: Three 71 had ranging from 9 mg/kg 20 within 4 months treatment onset. Myoclonus was characterized multifocal, involving...
Increasing cases of pulmonary aspergillosis (IPA) in immunocompetent patients with severe influenza have been reported. Howevere, the risk factors for occurence and death are largely unknown.Data hospitalised A-related pneumonia (FluA-p) obtained from five teaching hospitals 2031 to 2018, were reviewed. Univariate multivariate logistical regression analyses performed determine involved acquisition 60-day mortality IPA patients.Of 693 FluA-p included study, 3.0% (21/693) a 42.9% (9/21)....
Abstract Maize is China’s largest grain crop. Mechanical harvesting the key technology in maize production, and kernel moisture concentration (KMC) main controlling factor mechanical China. The dehydration rate (KDR) closely related to KMC. Thus, it important conduct genome-wide association studies (GWAS) of KMC KDR maize, detect relevant quantitative trait nucleotides (QTNs), mine candidate genes. Here, 132 inbred lines were used measure every 5 days from 10 40 after pollination (DAP) order...
Wheat bran is a traditional Chinese medicine; however, it mostly used as feedstuff in China. widely accepted an important ingredient many low-glycemic index foods modern western societies; its glycemic control mechanism unknown.To determine potent α-glucosidase inhibitory compounds from wheat and to identify the inhibition on α-glucosidase.Ethanolic extract of was prepared evaluate activity α-glucosidase, then fractionation guided by vitro enzyme-inhibition assay, were identified high...
Streptomyces lomondensis S015 synthesizes the broad-spectrum phenazine antibiotic lomofungin. Whole genome sequencing of this strain revealed a genomic locus consisting 23 open reading frames that includes core biosynthesis gene cluster lphzGFEDCB. lomo10, encoding putative flavin-dependent monooxygenase, was also identified in locus. Inactivation lomo10 by in-frame partial deletion resulted new metabolite, 1-carbomethoxy-6-formyl-4,9-dihydroxy-phenazine, along with absence This result...
Article5 March 2020Open Access Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia Bai-Liang He Division of Hematology, Department Medicine, Li Ka Shing Faculty The University Hong Kong, Kong SAR, China Guangdong Provincial Key Laboratory Biomedical Imaging, Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Province, Search for more papers by this author Ning Yang Cheuk Him Man Nelson Ka-Lam Ng Chae-Yin Cher Ho-Ching Leung Leo Lai-Hok Kan Bowie...
Inconsistencies exist regarding the severity of illness caused by different influenza strains. The aim this study was to compare clinical outcomes hospitalized adults and adolescents with influenza-related pneumonia (Flu-p) from type A B strains in China.We retrospectively reviewed data Flu-p patients five hospitals China January 2013 May 2019. Multivariate logistic Cox regression models were used assess effects virus subtypes on outcomes, explore risk factors 30-day mortality for...
Abstract Background The pneumonia severity index (PSI) and the CURB-65 (confusion, urea, respiratory rate, blood pressure, age ≥ 65 years) score have been shown to predict mortality in community-acquired pneumonia. Their ability influenza-related pneumonia, however, is less well-established. Methods A total of 693 laboratory-confirmed FluA-p patients diagnosed between Jan 2013 Dec 2018 recruited from five teaching hospitals China were included study. sample 494 derivation cohort 199...