A5101827796- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- RNA modifications and cancer
First Affiliated Hospital of Nanchang University
2020-2023
Nanchang University
2020-2023
Guangdong Medical College
2016
Guangdong Pharmaceutical University
2016
This study aimed to understand the exact function and potential mechanism of miR-4500 in colorectal cancer (CRC). In this study, expression was decreased both CRC cells tissues, downregulated indicated advanced tumor stage poor survival. By bisulfite sequencing analysis, we found that CpG island promoter region hypermethylated tissues compared with normal control non-tumor respectively. Functionally, gain- loss-of-function analyses suppressor role miR-4500: it suppressed cell proliferation,...
Background: The further progression of credible expression profiling analysis genes continues to expand our understanding the biological characteristics in lung cancer. In this study, RNA sequencing (RNA-Seq) was used contrast transcriptomics small cell cancer (SCLC) that acquired partial response (PR) and stable disease (SD)/progressive (PD) after first-line chemotherapy. We aimed illuminate underlying mechanisms long noncoding RNAs (lncRNAs) microRNAs (miRNAs) efficacy SCLC Methods: Six...