A5078660282- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Research Studies
- RNA modifications and cancer
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Treatments and Studies
- Circular RNAs in diseases
- Moyamoya disease diagnosis and treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Alcohol Consumption and Health Effects
- Copper-based nanomaterials and applications
- Genetic and Kidney Cyst Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Chronic Kidney Disease and Diabetes
- Dermatological and Skeletal Disorders
- Cancer Mechanisms and Therapy
- Nanoparticle-Based Drug Delivery
- Vehicle Routing Optimization Methods
- Hypertrophic osteoarthropathy and related conditions
- Endoplasmic Reticulum Stress and Disease
- Lung Cancer Diagnosis and Treatment
- Membrane Separation Technologies
- Autoimmune Bullous Skin Diseases
Wuhan University
2023-2025
Renmin Hospital of Wuhan University
2023-2025
Fifth Hospital of Shijiazhuang
2024
Peking University
2024
Peking University Third Hospital
2024
Beijing University of Chemical Technology
2023
Capital Medical University
2023
Shanghai Pulmonary Hospital
2018-2022
Tongji University
2018-2022
Peking Union Medical College Hospital
2019-2021
Abstract Circular RNA FOXO3 ( CircFOXO3 , also termed as Hsa_circ_0006404 ) is derived from exon 2 of forkhead box O3 gene, and abnormal expression shown in different diseases. However, whether circFOXO3 plays important roles tumorigenesis progression prostate cancer (PCa) remains unclear. In this study, we found that was up‐regulated both PCa tissues serum samples. Moreover, positively correlated with the Gleason score observed to be > 6 samples compared = Knock‐down could remarkably...
Moyamoya disease (MMD) is a cerebrovascular characterized by progressive stenosis of the intracranial internal carotid arteries and their proximal branches. However, etiology this rare remains unknown. Serum microRNA (miRNA) profiles have been screened to identify novel biomarkers prognostic values. Here, we identified serum miRNAs that might play an important role in pathogenesis MMD. A genome-wide miRNA array analysis two pooled samples from patients with MMD controls revealed 94...
Abstract To compare protein expression levels, gene mutation and survival among Right-Sided Colon Cancer (RSCC), Left-Sided (LSCC) rectal cancer patients, 57 cases of RSCC, 87 LSCC 145 patients were included retrospectively. Our results demonstrated significant differences existed regarding tumor diameter, differentiation, invasion depth TNM stage. No difference was identified in levels MLH1, MSH2, MSH6, PMS2, β-Tubulin III, P53, Ki67 TOPIIα, KRAS BRAF three groups. Progression Free Survival...
Background: The further progression of credible expression profiling analysis genes continues to expand our understanding the biological characteristics in lung cancer. In this study, RNA sequencing (RNA-Seq) was used contrast transcriptomics small cell cancer (SCLC) that acquired partial response (PR) and stable disease (SD)/progressive (PD) after first-line chemotherapy. We aimed illuminate underlying mechanisms long noncoding RNAs (lncRNAs) microRNAs (miRNAs) efficacy SCLC Methods: Six...
Background Immunotherapies may prolong the survival of patients with small-cell lung cancer (SCLC) to some extent. The role forkhead box protein P3 (FOXP3) in tumor microenvironment (TME) remains controversial. We aimed examine FOXP3-related expression characteristics and prognostic values develop a clinically relevant predictive system for SCLC. Methods enrolled 102 histologically confirmed SCLC at stages I–III. Through immunohistochemistry, we determined pattern FOXP3 its association other...
Abstract Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, and patients with HCC have a poor prognosis low survival rates. Establishing prognostic nomogram important for predicting HCC, as it helps to improve patient’s prognosis. This study aimed develop evaluate nomograms risk stratification predict overall (OS) cancer-specific (CSS) in patients. Data from 10,302 initially diagnosed were extracted Surveillance, Epidemiology, End Results (SEER) database between...
For the problems of long planning paths and slow convergence speed ant colony optimization (ACO) in mobile robot path planning, this paper improves introduces artificial potential field method (APF). Firstly, initial pheromone concentration is differentiated to make ants more directional at early stage algorithm. Second, heuristic factor function dynamically adjusted optimize update strategy so that algorithm can effectively distinguish high-quality from common ones. Finally, distance...
To investigate the expression level of E-cadherin in spinal plasma cell myeloma and its relationship with clinicopathological indexes myeloma. The was detected 41 cases 14 simple bone cysts by using S-P (streptavidin-perosidase) immunohistochemical staining. between clinicopathologica1 features analyzed. In myelomas, positive rate (46.34%) higher than that cyst tissues (all negative) (P<0.01). And had no obvious patients' age, gender, clinical classification or M-component (P>0.05), but...
To investigate the relationship between sleep status in first trimester and preterm birth.
Bifunctional electrocatalysts used for oxygen reduction and evolution reactions (ORR/OER) are of great significance metal-air batteries. Metal-organic frameworks (MOFs), after undergoing a high-temperature calcination process, emerge as promising precursors...
Background: The relationship between ischemic stroke (IS) and lipoprotein-associated phospholipase A2 (Lp-PLA2) activity is still unclear, there a dearth of stratified research on the Lp-PLA2 different IS subtypes. Therefore, Mendelian randomization (MR) was used in this study to examine genetically proxied risks its Methods: Based information from meta-analysis genome-wide association studies, which included 13,664 European people, five single nucleotide polymorphisms related were chosen as...
Objective: To compare the population characteristics, positive rate of screening, detection breast cancer, early diagnosis and cost between mass screening group opportunistic cancer. Methods: This study is a prospective multicenter cohort conducted from January 1, 2014 to December 31, 2016. The participants were enrolled for or After completing questionnaire, all received physical examination ultrasound every year 3 rounds by year. participants' characteristics results two groups compared χ2...
Platinum-based chemotherapy remains the essential therapy for small cell lung cancer (SCLC). Here, we conducted a statistical analysis to explore whether curative efficacy of 2-cycle platinum-based can predict survival patients with SCLC.
Abstract Background Immune therapy has achieved notable success in cancer treatment. A novel immunocheckpoint, Lymphocyte activing gene-3 (LAG-3), shown promising therapeutic efficacy non-small cell lung (NSCLC). However, literature about LAG-3 small (SCLC) is scarce. We statistically analyzed the correlation of expression with programmed death 1 (PD-1) and ligand (PD-1), its survival predictive significance, possibility becoming a treatment alternative SCLC. Methods In this study, we...