A5100427299- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Corneal surgery and disorders
- Retinal Development and Disorders
- Lung Cancer Research Studies
- Retinal Imaging and Analysis
- Salivary Gland Tumors Diagnosis and Treatment
- Traumatic Ocular and Foreign Body Injuries
- Retinal and Macular Surgery
- Nasolacrimal Duct Obstruction Treatments
- Retinoids in leukemia and cellular processes
- Flavonoids in Medical Research
- Facial Trauma and Fracture Management
- Ocular Surface and Contact Lens
- Ocular and Laser Science Research
- Cancer Immunotherapy and Biomarkers
- Pancreatic and Hepatic Oncology Research
- Anesthesia and Sedative Agents
- Nausea and vomiting management
- Inflammatory Biomarkers in Disease Prognosis
- Retinopathy of Prematurity Studies
- Drug-Induced Ocular Toxicity
- Pharmacological Receptor Mechanisms and Effects
- IL-33, ST2, and ILC Pathways
Chengde Medical University
2025
Zunyi Medical University
2022
Hebei University of Technology
2022
Shandong University
2022
Leshan Normal University
2022
Xuzhou Medical College
2020
Nanjing Drum Tower Hospital
2020
Shanghai Pulmonary Hospital
2020
Tongji University
2020
Changshu No.1 People's Hospital
2018
purpose. To quantify the extent and pattern of retinal ganglion cell (RGC) loss in DBA2/NNia glaucomatous mouse strain as a function age compare it with nonglaucomatous strain. methods. All cells retinas DBA/2NNia C57/BL6 mice various ages (five eyes per group 3-month intervals from 3 to 18 months age) were counted. A novel counting method that does not rely on sampling uses retrograde labeling RGCs Fluorogold (Fluorochrome; Englewood, CO) was used. RGC contrasted C57 at same ages. The total...
Diabetic retinopathy, a severe complication of diabetes, is the leading cause blindness in developed world. This study investigated effects quercetin on levels monocyte chemoattractant protein-1 (MCP-1), matrix metalloproteinase-9 (MMP-9) and vascular endothelial growth factor (VEGF) serum rats with diabetic explored functional mechanisms treatment retinopathy. Twenty induced diabetes were divided into model group group, 10 each group. Ten healthy also included to serve as control Rats...
To determine the effect of intraocular pressure (IOP) elevation on glutamate-induced expression glutamine synthetase (GS) in retinal Müller cells rat eyes.Six groups three rats each were studied. Group I was a normal control group. In II, one eye received an intravitreal glutamate injection (75 nmoles) while contralateral served as control. Groups III and IV, IOP raised by episcleral vein cauterization. Moderately elevated maintained for 1 day or week IV (35 +/- 1.9-45 5.2 mm Hg). An...
purpose. To evaluate the relationship between retinal ganglion cell (RGC) size, density distribution, and survival in senescent DBA2/NNia mice that develop pigmentary glaucoma. validity of nearest neighbor distance (NND), a measure focal for surviving RGCs retina, as method to quantify RGC loss mice. methods. Fifteen-month-old were labeled retrogradely with fluorogold. Retinas flat mounted imaged their entirety using an epifluorescence microscope motorized stage. Digital maps wholemounts...
Immune therapy has shown good results in small-cell lung cancer (SCLC), but the impact of immune microenvironment disease is unclear. In this work, we detected expression programmed death 1 (PD-1), PD-ligand (PD-L1), and other biomarkers cancer. We also analyzed correlations between these markers survival SCLC.Protein PD-1, PD-L1, PD-L2, CD3, CD4, CD8, FOXP3 was surgical tissues from 102 SCLC patients by immunohistochemistry.Positive PD-1 on tumor-infiltrating lymphocytes (TILs) found 40.2%...
Abstract Background To observe the effect of pretreatment with ketorolac tromethamine on sufentanil-induced cough in general anesthesia patients. Methods A total 102 patients were screened, and 90 scheduled for elective surgery under anesthesia. The randomly divided into two groups: control group (C group) observation (KT group). Five minutes before induction, was given 0.5 mg/kg intravenously within 3 s, while same amount normal saline intravenously. All a sufentanil bolus μg/kg (within s)...
Iridoids are a special class of cyclopentanoid monoterpenes, which exhibit wide range biological effects. The present study aimed to investigate the potential effects three iridoids genipin, geniposide and geniposidic acid on human oral squamous cell carcinoma (OSCC) lines HSC-2, SCC-9 A253 in addition studying possible underlying mechanisms. Cell viability assay revealed that treatment significantly suppressed proliferation all cancer lines. In addition, induced cycle arrest at G2/M phase...
Recent studies report that increased corneal edema because of contact lens wear under closed lids is associated with elevated Goldmann intraocular pressure (GAT IOP). We sought to assess whether the impact postoperative on GAT IOP would be similar and determine differential effect different amounts edema.The setting a tertiary level cataract clinic in Shantou, China. Pre- (day 1) IOP, central thickness (CCT), hysteresis, resistance factor, radius curvature were measured for consecutive...
Age-related macular degeneration (AMD) is the leading cause of blindness in elderly population. Evidence has shown that human immune system may play critical roles this disease. Inducible costimulator (ICOS) promotes T-cell activation, differentiation, and T:B-cell interactions. The aim study was to understand effect ICOS on development AMD from genetic polymorphism perspective serum level perspective. Two polymorphisms, rs10183087A/C rs10932037C/T, were tested 223 cases 262 healthy...
Observation studies have postulated that atopic eczema is associated with a risk of inflammatory bowel disease in the East Asian population; however, this association does not obviate biases resulting from confounding effects and reverse causation. This study aimed to determine whether causal population using bidirectional two-sample Mendelian randomization design. Independent genetic variants obtained public genome-wide for (4296 cases, 163 807 controls) were extracted estimate on (2824...
Dacryoliths in lacrimal gland ductule are a rare condition and an unusual cause of conjunctivitis. Here we report case with large stone unique hairy nucleus.A 38-year-old female presented red left eye for one month. Physical examination revealed inflammatory granuloma the lateral canthus fistula purulent secretion. Antibiotics did not ameliorate symptoms. After incised fistula, huge dacryolith (10 mm × 5 3 mm) was identified at end dilated removed surgically. Histopathologic showed nucleus...
Primary angle-closure glaucoma (PACG) is a major cause of blindness worldwide, with particularly high prevalence in Asian populations. Laser iridotomy (LI) has been the standard therapeutic modality for treating PACG to avoid blindness. However, complex structure eyeball, aqueous fluidity, and limitation detecting equipment will difficulty surgery probability complications. Numerical simulation was conducted investigate humor (AH) flow under different physiological structures before after...
Objective To compare the ocular biometry and build up normative database in cataract patients older than 50 years from Tibet,Xinjiang Guangdong.To provide reference data for patient different areas.Methods This study nonrandomly selected one thousand nine hundred ninty four eyes 1 994 subjects aged ＞50 years.Subjects Guangdong were 249,615 080 respectively.All received surgeries on Lifeline Express 2007 to 2008.A-scan ultrasound auto keratometer used measure axial length (AL),anterior...
Abstract Background Immune therapy has achieved notable success in cancer treatment. A novel immunocheckpoint, Lymphocyte activing gene-3 (LAG-3), shown promising therapeutic efficacy non-small cell lung (NSCLC). However, literature about LAG-3 small (SCLC) is scarce. We statistically analyzed the correlation of expression with programmed death 1 (PD-1) and ligand (PD-1), its survival predictive significance, possibility becoming a treatment alternative SCLC. Methods In this study, we...
Objective To investigate the therapeutic effect of 25 G+ vitrectomy assisted with preoperative intravitreal injection Ranibizumab for treatment proliferative diabetic retinopathy. Methods A prospective controled analysis in 74 eyes 73 cases retinopathy treated by from May 2013 to January 2015 was performed. Thirty-four 33 received 0.05ml(contain ranibizumab 0.5mg)at 5 7 days before group A. Forty 40 were only as non-injection (group B). The operative time, hemorrhage during operation,...
Our aim was to prepare a radioactive lacrimal passages probe, study its dose distribution in phantom and suggest security indexes therapeutic effective doses for brachytherapy. We prepared the probes by laying 125I particles into plastic tubes. conducted temperature tests, pressure soak tests shock obtain indexes. The distributions wax matrix were also detected, surface rates on different parts of absorbed operator examined. passage probe demonstrated no form changes when using contamination...
Abstract Background Ocular trauma is complex and varied, some occult intraocular foreign bodies (IOFBs) can lead to uncommon symptoms signs. We report a case of rhegmatogenous retinal detachment (no obvious wound, no pain, infection or other symptoms) caused by an aluminium body, which could have been easily missed. Case presentation A 42-year-old male presented the outpatient department our hospital complaining fluttering black dots decreased vision in his left eye that began 3 months...
Objective To evaluate the effect of phacoemulsification with intraocular lens (IOL)im-plantation after extra-filtering surgery.Methods Phacoemulsification implantation IOL was performed on 46 cataract eyes angle closure glaucoma patients surgery (Test),and 54 ( Control ).All case received phacoemulsifieation by one surgeon.The visual acuity, corneal edema,endothelial cell loss,IOP and damage iris were compared between two groups.Results All without complications such as posterior capsular...