A5014723812- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Diabetes and associated disorders
- Diabetes Management and Research
- Peroxisome Proliferator-Activated Receptors
- Retinal Development and Disorders
- Corneal Surgery and Treatments
- Photoreceptor and optogenetics research
- Pharmacological Effects of Natural Compounds
- Vascular Malformations Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Traumatic Ocular and Foreign Body Injuries
- Advanced Glycation End Products research
- Ocular and Laser Science Research
- Nitric Oxide and Endothelin Effects
- Cardiovascular Function and Risk Factors
- Biochemical effects in animals
- Skin Diseases and Diabetes
- Biochemical Acid Research Studies
- Lipid metabolism and disorders
- Sympathectomy and Hyperhidrosis Treatments
General Hospital of Guangzhou Military Command
2012-2025
Third Affiliated Hospital of Southern Medical University
2019-2024
China Three Gorges University
2011-2023
Central South University
2023
Zhuhai People's Hospital
2023
Second Xiangya Hospital of Central South University
2023
Yichang Central People's Hospital
2008-2021
Second Military Medical University
2009
Charité - Universitätsmedizin Berlin
2005
To address the impact of corneal edema on transparency, we proposed an improved Monte Carlo (MC) method that uses a cost-effective and easily applicable approach to extract fibril features. This aims enhance computational accuracy elucidate microscopic mechanisms transparency. Fresh ex vivo porcine corneas were immersed in deionized water simulate various states edema. For each state, carefully analyzed its transparency fibrous conditions. The diameter spatial distribution fibrils measured...
BACKGROUND:To investigate the prognostic value of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), and pancreatic stone (PSP) in children with sepsis. MATERIAL AND METHODS:A total 214 patients sepsis during hospitalization were enrolled. Serum levels PCT, hs-CRP, PSP measured on day 1 survival rates recorded after a follow-up 28 days. Pearson's correlation analysis was conducted to test association pediatric critical illness score (PCIS). Logistic regression models used...
To investigate the effect of tissue factor targeting peptide (TF-TP) on retinal pigment epithelium (RPE) cells tight junctions.Cell counting kit-8 (CCK-8) was used to measure proliferation ARPE-19 cells. Expression junction, ZO-1 in measured by Western blot and immunofluorescent staining. also detect expression (TF). CEC Transmigration Assay migration The transport fluorescent markers [fluorescein isothiocyanate dextrans 4, 10, 20 (FD4, FD10, FD20)] transepithelial electrical resistance...
Elderly patients with Alzheimer's disease (AD) often have multiple underlying disorders that lead to frequent hospital admissions and are associated adverse outcomes such as in-hospital mortality. The aim of our study was develop a nomogram be used at admission for predicting the risk death in AD during hospitalization.We established prediction model based on dataset 328 hospitalized -who were admitted discharged from January 2015 December 2020. A multivariate logistic regression analysis...
Wet age-related macular degeneration which incidence increases year by is a blinding eye disease, but current clinical methods of treatment on this disease are limited and the outcome not ideal. Recent studies have found abnormally high expression tissue factors targets for wet to achieve certain effect in choroidal neovascularization. Related literatures reviewed as following.
Age-related macular degeneration (AMD) is the leading cause of blindness in elderly population. Evidence has shown that human immune system may play critical roles this disease. Inducible costimulator (ICOS) promotes T-cell activation, differentiation, and T:B-cell interactions. The aim study was to understand effect ICOS on development AMD from genetic polymorphism perspective serum level perspective. Two polymorphisms, rs10183087A/C rs10932037C/T, were tested 223 cases 262 healthy...
To evaluate the protective effects of lipoic acid-niacin (N2L) dimers against blue light (BL)-induced oxidative damage to human retinal pigment epithelium (hRPE) cells in vitro.hRPE were divided into a control group (CG), BL group, an N2L plus irradiation α-lipoic acid (ALA) ALA-only and N2L-only group. hRPE cellular viability was detected by performing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) bromide assays, apoptosis evaluated annexin-V-PE/7-AAD staining followed flow...
To assess the utility and efficiency of endoscopy-assisted vitrectomy (EAV) for treatment corneal opacity in severe ocular trauma.
Objective: To analyze the changes of plasma aldosterone (ALD) and angiotensin II (Ang II) levels in patients with ischemic cardiomyopathy (ICM) combined Type-2 diabetes mellitus (T2DM) their clinical significance.
 Methods: Sixty-eight ICM T2DM fifty-two simple treated People’s Hospital Three Gorges University/the First Yichang from February 2018 to 2021 were selected as observation group control group, respectively. All had intervention same neuroendocrine hormone regime. The ALD Ang...
Background Light-induced retinal damage results in the of retinl pigment epithelial (RPE) cells and therefore affects pathogenesis development age-related macular degeneration (AMD). Studies showed that tissue factor (TF) is overexpressed oxidative damaged RPE choroidal neovascularization (CNV) AMD, speculating suppression TF can prevent inhibit CNV. Objective This study was conducted to observe protective effects targeting peptide (TF-TP), a new drug autologous synthesis, on human...
Background Researches showed that mitochondria and oxidative stress play a crucial role in retinal photochemical injury,but the relationship between damage of human pigment epithelium (RPE) cell-induced by blue light light-irradiated time is less studied. Objective The aim this study was to research possible mechanism RPE induced vitro. Methods Human cells were isolated from healthy donors cultured.The divided into normal control group exposure group.The irradiated using...
Objective To observe the function of blood-aqueous barrier(BAB) after transscleral sulcus suture intraocular lens (IOL) fixation under endoscope guidance.Methods 39 eyes 38 cases were enrolled in this study.Endoscope-assissted IOL was performed 33 eyes,of which 21 eyeball contusion or foreign body injury,3 endogenous endophthalmitis,and 9 proliferative diabetic retinopathy.A foldable fixed ciliary sulcus.3 underwent phacoemulsification combined with implantation and 3 regular without...
Abstract High glucose (HG)-induced endothelial cell senescence can induce atherosclerosis and is closely related to the vascular complications of diabetes. Amlexanox (AM), a selective IKKε inhibitor, protect against metabolic diseases. This study examined how amlexanox inhibits under high conditions explores its mechanisms action .. HUVECs were incubated with HG (33 mmol/L), then was targeted shRNA lentivirus transfection or treatment amlexanox. Cellular indicators by SA-β-gal staining,...