A5102917553- Colorectal Cancer Surgical Treatments
- Advanced Optical Sensing Technologies
- Colorectal and Anal Carcinomas
- Genetic factors in colorectal cancer
- Spectroscopy and Chemometric Analyses
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Medical Imaging Techniques and Applications
- RNA Interference and Gene Delivery
- Colorectal Cancer Treatments and Studies
- Cancer, Lipids, and Metabolism
- Gastric Cancer Management and Outcomes
- Electronic Health Records Systems
- Surface Roughness and Optical Measurements
- Human Pose and Action Recognition
- Advanced Radiotherapy Techniques
- Cancer therapeutics and mechanisms
- MRI in cancer diagnosis
- Peroxisome Proliferator-Activated Receptors
- Advanced Neuroimaging Techniques and Applications
- Primary Care and Health Outcomes
- Autonomous Vehicle Technology and Safety
- Medical Coding and Health Information
- Optical Systems and Laser Technology
- Advanced Measurement and Metrology Techniques
Xijing University
2022-2024
Huzhou University
2023-2024
Zhejiang University
2023-2024
Second Military Medical University
2017-2024
Changhai Hospital
2017-2024
Shanghai Cancer Institute
2021
Jiangyin People's Hospital
2012-2018
Southeast University
2012-2018
Jinan Military General Hospital
2012-2015
Chongqing University of Science and Technology
2014
Abstract Mutations in KRAS exon 2, BRAF and PIK3CA are commonly present colorectal cancer (CRC) worldwide, but few data about RAS mutations outside 2 available for Chinese CRCs. We, therefore, determined the mutation frequencies prognostic values of 3 4, NRAS 3, 9 20, 15 by PCR direct sequencing 353 CRC patients from two clinical centers. , were identified 42.2%, 4.5%, 12.3% cases, respectively. We found “rare mutations” genes nearly 14% CRCs-i.e., almost a quarter (24.0%) wild type CRCs,...
Background: Next generation sequencing (NGS)-based multi-gene panel tests have been performed to predict the treatment response and prognosis in patients with colorectal cancer (CRC). Whether mutation results of formalin-fixed paraffin-embedded (FFPE) tissues are identical those fresh frozen remains unknown. Methods: A 22-gene 103 hotspots was used detect mutations paired tissue FFPE from 118 CRC. Results: In our study, 117 (99.2%) had one or more variants, 226 variants 221 tissue. Of 129...
Abstract To compare protein expression levels, gene mutation and survival among Right-Sided Colon Cancer (RSCC), Left-Sided (LSCC) rectal cancer patients, 57 cases of RSCC, 87 LSCC 145 patients were included retrospectively. Our results demonstrated significant differences existed regarding tumor diameter, differentiation, invasion depth TNM stage. No difference was identified in levels MLH1, MSH2, MSH6, PMS2, β-Tubulin III, P53, Ki67 TOPIIα, KRAS BRAF three groups. Progression Free Survival...
Abstract: Pancreatic cancer is a highly lethal disease with 5-year survival rate less than 5% due to the lack of an early diagnosis method and effective therapy. To provide novel diagnostic targeted therapy for pancreatic cancer, multifunctional nanoimmunoliposome high loading ultrasmall superparamagnetic iron oxides (USPIOs) doxorubicin (DOX) was prepared by transient binding reverse-phase evaporation method, conjugated anti-mesothelin monoclonal antibody post-insertion target...
Roadside perception is a challenging research area that presents even greater difficulties than vehicle perception. Due to the different locations and angles of cameras, roadside objects exhibit violent multiscale variations, while vast sensing field introduces more small-scale targets complex backgrounds, making target recognition challenging. To address these problems, we focus on position information encoding achieve accurate object detection by proposing enhancement faster network...
The basic helix-loop-helix transcription factor activating enhancer‑binding protein (AP)-4 has been found to be involved in tumor biology. However, the role of AP-4 non-small cell lung cancer (NSCLC) yet elucidated. present study aimed investigate expression NSCLC. as analyzed using quantitative polymerase chain reaction and western blot analyses 42 fresh NSCLC samples matched adjacent noncancerous tissues. Immunohistochemistry was performed assess clinical significance tissues patients...
Lidar has the advantages of high accuracy, resolution, and is not affected by sunlight. It been widely used in many fields, such as autonomous driving, remote sensing detection, intelligent robots. However, current lidar detection system belongs to weak signal generally uses avalanche photoelectric detector units detectors. Limited technology, photosensitive surface small, receiving field view limited, it easy cause false alarms due background light. This paper proposes a method based on...
This study was conducted to compare the clinical curative effect and acute radiation lung reactions between CyberKnife (CK) three-dimensional conformal radiotherapy (3DCRT) treatment for inoperable stage I peripheral non-small-cell cancer (NSCLC). We retrospectively analyzed 68 patients with NSCLC 2012 2013 in our institution. The CK were treated 42-60 Gy three fractions, while 3DCRT a total of 60 Gy, at 2 per fraction. followed up outcome evaluated according Response Evaluation Criteria...
Peroxisome proliferator-activated receptor-γ (PPAR-γ) is important in tumor differentiation, proliferation and apoptosis. However, the effect mechanism of PPAR-γ on promotion cisplatin sensitivity glioma cells remain to be elucidated. The present study established cisplatin-resistant U-87 MG/CDDP cell lines overexpressing PPAR-γ. With upregulated expression PPAR-γ, cancer was increased. Flow cytometry revealed that intracellular content rhodamine-123 increased, P-glycoprotein downregulated,...
Background In most guidelines, upper rectal cancers (URC) are not recommended to take neoadjuvant or adjuvant radiation. However, the definitions of URC vary greatly. Five had been commonly used define URC: 1) >10 cm from anal verge by MRI; 2) >12 3) colonoscopy; 4) 5) above anterior peritoneal reflection (APR). We hypothesized that fifth definition is optimal identify patients with cancer avoid Methods The data stage II/III who underwent radical surgery without preoperative...
The aim of the study was to preparation matrine liposome and its activity for resisting cells, by orthogonal design, observe inhibiting effect on glioma through MTT method, Flow Cytometer, electron microscope. results showed that we take encapsulation efficiency as index; optimal is 100 mg lecithin, 40 cholesterol, phosphate buffered saline (PBS) with pH value 6.4, matrine. result testing shown tested group medium high dosage (0.75, 1.0, 1.25 mg/L) has significant rate growth BT 325 cells....
BACKGROUND: Radiotherapy with or without chemotherapy has been widely used to improve patient outcomes due locally advanced rectal cancer. The differential degree of pelvic fibrosis and anorectal function after preoperative postoperative chemoradiotherapy not studied previously. METHODS: Data patients who received radical resection cancer in our hospital from January 2000 Aug 2021 were retrospectively analyzed. Anastomotic scores perirectal based on magnetic resonance imaging findings...
Based on structure and composition characteristics of engine oil, the new algorithm for its Infrared Spectrum (IR) Identification has been put forward. The Hit Quality Index Related are widely used in recently. two methods don’t take importance variables into consideration cannot distinguish unobvious variation IR spectra. Therefore diversity weight factor was introduced to promote selectivity. experimental results had shown that spectrum similarity evaluation index could variations improve...
A new method for determination of antioxidants in jet fuels, which is based on the differential pulse voltammetric characteristics antioxidant 2,6-ditertbutyl-4-methylphenol solution saturated KOH anhydrous ethyl alcohols, established. The experimental results have shown that there a linear relationship between content 2,6-ditertbutyl-4-Methyl-phenol fuel and voltammetry response electrolytic solution. It has also been contents can be reliably simply determined with help standard addition...
Excellent time slot allocation algorithms can quickly, reasonably and accurately allocate resources according to node service requirements meet the real-time transmission of tactical information in data chains ensure with reliable delay jitter. In order solve problems uneven failure chains. this paper, based on study techniques for Link 16 chains, an adaptive weight mechanism is introduced into PSO algorithm, thus proposing a new algorithm particle swarm optimization (AWPSO-SAA). The...