A5043809950- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Fluid Dynamics and Vibration Analysis
- Aerodynamics and Fluid Dynamics Research
- Wind and Air Flow Studies
- Colorectal Cancer Treatments and Studies
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Structural Behavior of Reinforced Concrete
- Stoma care and complications
- Structural Load-Bearing Analysis
- Diverticular Disease and Complications
- Cancer-related molecular mechanisms research
- Appendicitis Diagnosis and Management
- Cancer Genomics and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Inflammatory Biomarkers in Disease Prognosis
- Structural Engineering and Vibration Analysis
- Esophageal and GI Pathology
- Advanced Radiotherapy Techniques
- RNA modifications and cancer
- Anorectal Disease Treatments and Outcomes
Changhai Hospital
2011-2025
Second Military Medical University
2012-2025
Guangzhou University of Chinese Medicine
2024
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2024
Northwest A&F University
2021-2023
Shenyang Pharmaceutical University
2023
University of Groningen
2022
Southwest Hospital
2022
Shanghai Cancer Institute
2022
University Medical Center Groningen
2022
Cellulose based ZnO nanocomposite (RCZ) films were prepared from cellulose carbamate–NaOH/ZnO solutions through one-step coagulation in Na2SO4 aqueous solutions. The structure and properties of RCZ characterized using XRD, FTIR, XPS, SEM, TEM, TG, tensile testing, antibacterial activity tests. content was obtained the range 2.7–15.1 wt %. nanoparticles with a hexagonal wurtzite agglomerated into large particles, which firmly embedded matrix. displayed good mechanical high thermal stability....
Background: Next generation sequencing (NGS)-based multi-gene panel tests have been performed to predict the treatment response and prognosis in patients with colorectal cancer (CRC). Whether mutation results of formalin-fixed paraffin-embedded (FFPE) tissues are identical those fresh frozen remains unknown. Methods: A 22-gene 103 hotspots was used detect mutations paired tissue FFPE from 118 CRC. Results: In our study, 117 (99.2%) had one or more variants, 226 variants 221 tissue. Of 129...
Abstract To compare protein expression levels, gene mutation and survival among Right-Sided Colon Cancer (RSCC), Left-Sided (LSCC) rectal cancer patients, 57 cases of RSCC, 87 LSCC 145 patients were included retrospectively. Our results demonstrated significant differences existed regarding tumor diameter, differentiation, invasion depth TNM stage. No difference was identified in levels MLH1, MSH2, MSH6, PMS2, β-Tubulin III, P53, Ki67 TOPIIα, KRAS BRAF three groups. Progression Free Survival...
Objective: To explore the safety and efficacy of neoadjuvant chemoradiotherapy (nCRT) combined with a PD-1 antibody in improving complete clinical response (cCR) organ preservation patients ultra-low rectal cancer. Methods: This was prospective phase II, single-arm, open-label trial. Patients confirmed pMMR status T 1-3a N 0-1 M 0 retcal adenocarcinoma were included. Long-course delivered to dose 50 Gy. A added 2 weeks after first radiotherapy session, two courses administered. After...
In current research, the anchoring performance of prestressed Carbon Fiber Reinforced Polymer (CFRP) plate anchors is primarily acquired through experimental methods, which makes it difficult to capture internal deformation and stress distribution anchor. this paper, a model grouted cylindrical wedge anchor for CFRP plates established using finite element analysis software ABAQUS. The simulation replicates processes relaxation at release end second tensioning end, geometrically nonlinear...
Abstract Background Early detection of colorectal carcinoma (CRC) would help to identify tumors when curative treatments are available and beneficial. However, current screening methods for CRC, e.g., colonoscopy, may affect patients’ compliance due the uncomfortable, invasive time-consuming process. In recent decades, methylation profiles blood-based circulating tumor DNA (ctDNA) have shown promising results in early multiple tumors. Here we conducted a study investigate performance ctDNA...
e15603 Background: Neoadjuvant chemoradiotherapy (nCRT) not only could bring tumor downsizing and downstaging but also achieve clinical complete response (cCR) or pathological (pCR). Although immunotherapy benefits MSI-H/dMMR rectal cancer patients, little is observed in MSS/pMMR patients. Several trials including VOLTAGE trial demonstrated that a combination of PD-1 inhibitor nCRT result promising even But the elucidation regarding organ preservation after treatment lacking. Watch Wait...
Background: Competing endogenous RNA (ceRNA) regulation is a novel hypothesized mechanism that states molecules share common target microRNAs (miRNAs) and may competitively combine into the same miRNA pool. Methods: Zinc finger protein 148 (ZNF148) TOP2A expression were analyzed in 742 colorectal cancer (CRC) tissues using immunohistochemistry (IHC). ZNF148 mRNA, miR101, miR144, miR335, miR365 estimated 53 fresh frozen CRC by reverse transcription polymerase chain reaction. Mechanisms...
Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive growth, and characterized by early tissue invasion metastasis with poor prognosis. Identifying prognostic markers delineating the underlying mechanisms that promote progression of PDAC are important treatment pancreatic cancer. TIP30, a newly identified tumor suppressor, appears to be involved in multiple processes during development metastasis. Here, we investigated expression TIP30 value patients. We examined...
Abstract Carbapenemase-producing E. coli is a grave public health concern as the potential emergence of resistant strains and their transmission. Isoorientin belongs to antimicrobial flavonoid compound existing in several plants, while research on activity isoorientin limited thus far. We evaluated antibiofilm effects against biofilm-forming carbapenem non-sensitive Escherichia (E. coli) from raw milk goats, explored its molecular mechanisms. showed obvious ability with minimum inhibitory...
The grid-generated turbulence in wind tunnel is commonly applied aerodynamic performance experiments of various industrial structures.However, the characteristics and application conditions are often affected by grid shape test position, respectively.Therefore, order to clarify influence position on tunnel, a computational fluid dynamics (CFD) numerical study generated two different grids was presented herein, with experimental validation.Firstly, time histories speed at 19 monitoring points...