A5078012082- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Colorectal and Anal Carcinomas
- Pelvic floor disorders treatments
- Diverticular Disease and Complications
- Gastrointestinal motility and disorders
- Stoma care and complications
- Colorectal Cancer Screening and Detection
- HIV, TB, and STIs Epidemiology
- Power Transformer Diagnostics and Insulation
- Elbow and Forearm Trauma Treatment
- Bladder and Urothelial Cancer Treatments
- Hip disorders and treatments
- Cancer Immunotherapy and Biomarkers
- HIV/AIDS Research and Interventions
- Pneumocystis jirovecii pneumonia detection and treatment
- Ferroptosis and cancer prognosis
- Metastasis and carcinoma case studies
- HIV-related health complications and treatments
- Cancer Mechanisms and Therapy
- Bone and Joint Diseases
- Hernia repair and management
- Enhanced Recovery After Surgery
- Cancer Genomics and Diagnostics
- Orthopaedic implants and arthroplasty
Changhai Hospital
2021-2025
Second Military Medical University
2021-2025
Yangpu Hospital of Tongji University
2024
Pudong New Area People's Hospital
2024
Tianjin Medical University
2020-2021
Xiangya Hospital Central South University
2018-2021
Central South University
2018-2021
First Hospital of China Medical University
2021
National Health and Family Planning Commission
2017
China Medical University
2017
Objective: To explore the safety and efficacy of neoadjuvant chemoradiotherapy (nCRT) combined with a PD-1 antibody in improving complete clinical response (cCR) organ preservation patients ultra-low rectal cancer. Methods: This was prospective phase II, single-arm, open-label trial. Patients confirmed pMMR status T 1-3a N 0-1 M 0 retcal adenocarcinoma were included. Long-course delivered to dose 50 Gy. A added 2 weeks after first radiotherapy session, two courses administered. After...
e15603 Background: Neoadjuvant chemoradiotherapy (nCRT) not only could bring tumor downsizing and downstaging but also achieve clinical complete response (cCR) or pathological (pCR). Although immunotherapy benefits MSI-H/dMMR rectal cancer patients, little is observed in MSS/pMMR patients. Several trials including VOLTAGE trial demonstrated that a combination of PD-1 inhibitor nCRT result promising even But the elucidation regarding organ preservation after treatment lacking. Watch Wait...
Conformal sphincter preservation operation (CSPO) is a for very low rectal cancers. Compared to intersphincteric resection (ISR), CSPO retains more dentate line and distal wall, also avoids damaging the nerves in space. This study aimed compare postoperative anal function quality of life between ISR.Patients with cancer undergoing (n = 117) ISR 66) were included from Changhai Huashan Hospital, respectively, 2011 2020. A visual analog scale (range 0-10) was utilized evaluate satisfaction...
To investigate the learning curve of conformal sphincter preservation operation (CSPO) in treatment ultralow rectal cancer and to further explore influencing factors time.From August 2011 April 2020, 108 consecutive patients with underwent CSPO by same surgeon Department Colorectal Surgery Changhai Hospital. The moving average cumulative sum control chart (CUSUM) were used analyze curve. preoperative clinical baseline data, postoperative pathological complications, survival data compared...
To assess postoperative anal function and quality of life ultra-low rectal cancer patients treated by laparoscopic modified Parks surgery.From February 2017 to March 2019, 114 with above T2 were respectively anterior resection (Dixon), coloanal anastomosis (modified Parks), Miles according the preoperative stage anastomotic position. The Fecal Incontinence Quality Life Scale (FIQL) each patient collected synthetically analyzed.Compared Dixon group, FIQL in group poor at early stage. However,...
Abstract Background This study aimed to compare the prevalence and symptoms of fecal incontinence (FI) in relation irritable bowel syndrome (IBS‐associated FI), constipation (constipation‐associated isolation (isolated FI). Methods Data were analyzed from 3145 respondents without organic comorbidities known influence defecation function general Chinese population who filled online Groningen Defecation Fecal Continence questionnaire. FI, IBS, evaluated with Rome IV criteria. Key Results The...
This paper proposes a real-time power line loss detection technology based on information engineering drive, firstly, through the algorithmic process of detection, method is determined. Secondly, by analyzing redundancy relationship independent components in distribution networks, drive used to improve accuracy calculation, so as reflect historical level. Finally, accurate realized solving discriminant function support vector machine. Simulation experiment results show that proposed this has...
Colon cancer presenting as a large abdominal mass accompanied by abscess and rupture is rare prone to be misdiagnosed delayed. In addition, the treatment plan not clear when combined with wall metastasis.
<title>Abstract</title> <bold>Objective</bold> To explore the single-center clinical experience of polydocanol foam in antithrombotic treatment mixed hemorrhoid patients with bleeding and review related literature.<bold>Methods</bold> From March 2018 to May 2023, we retrospectively analyzed data 7 who were admitted General Surgery Department Yangpu Hospital affiliated Tongji University. Patients therapy combined failed receive conservative need be treated injection sclerotherapy. We...
To investigate the feasibility and therapeutic effect of laparoscopy combined with total intersphincteric resection (Total-ISR) for extremely low rectal cancer. Methods: We performed Total-ISR in 45 patients cancer (1.0 cm≤the lower edge tumor to anal edge≤3.0 cm) from January 2014 December 2016. The operation time, blood loss, margin overall incidence postoperative complications were observed. rate local recurrence distant metastasis after surgery during median following-up time 20.5 months...
To review the research progress of wrist arthroscopy assisted treatment distal radius fractures.To summarize and describe anatomical characteristics fracture classification radius, indications contraindications arthroscopy-assisted treatment, surgical methods, associated soft tissue injuries, advantages disadvantages operation through a large number literature at home abroad on fractures by arthroscopy.Wrist as minimally invasive technique for fractures, compared with traditional surgery,...
To summarize the current progress of vascularized bone grafting in treatment osteonecrosis femoral head (ONFH), and to provide reference for ONFH.The literature at home abroad on ONFH with was reviewed, mechanism, operating methods effectiveness, indications, complications were summarized.Vascularized is a commonly used clinical hip-preserving operation. By replacing necrotic tissue bone, it can rebuild blood circulation system, promote healing area, biomechanical support area head, prevent...
Objective: To investigate the risk factors on antiretroviral therapy (ART) among HIV/AIDS positive students in Shenyang. Methods: A cross-sectional study was conducted aged between 15 and 30, an HIV-treatment-designated hospital Shenyang city, during 2007-2015. Data were analyzed by multivariate logistic regression mode to identify related ART. Results: total of 2 379 patients attended 6.1% (146/2 379) them students, All males, with homosexual transmission accounted for 93.2% (136/146). The...
Abstract Background: Cancer is still the leading cause of death in humans, and fourth colorectal cancer. Tumor bioinformatics has been developing recent years, prognosis quality life patients can be improved by using relevant tools to understand molecular pathogenesis cancer related prognostic markers. Methods: In this study, Bioinformatics analysis snp-related data colon from TCGA database, it was found that expression levels 4 mutated genes (CTTNBP2,DAPK1, DMXL1,SPTBN2) were significantly...
Abstract Background: This study investigated the prevalence, characteristic symptoms and risk factors of constipation in Chinese population. Methods: Data 3450 respondents from general population who completed digital Groningen Defecation Fecal Continence (DeFeC) questionnaire were analyzed. The non-comorbidity subgroup was defined as without organic comorbidities known to influence defecation. Constipation dyssynergic defecation prevalence severity evaluated using Rome IV criteria Renzi...
Abstract Background: This study was performed to investigate the gaps among patient-reported data, physician-reported and laboratory test data in human immunodeficiency virus (HIV)-infected patients detect potential risk factors for awareness gap. Methods: We included from 38 hospitals China. Patient-reported on four typical noninfectious comorbidities (NICMs) (osteoporosis, kidney disease, neuropsychiatric comorbidities, atherosclerotic cardiovascular disease (ASCVD)) were collected....
To investigate the clinical efficacy of laparoscopic modified Parks operation on patients with ultra-low rectal cancer.
Abstract Background: To investigate the learning curve of conformal sphincter preservation operation (CSPO) in treatment ultra-low rectal cancer and to further expore influencing factors time. Methods: From August 2011 April 2020, 108 consecutive patients with underwent CSPO by same surgeon department colorectal surgery Changhai Hospital. The moving average cumulative sum control chart (CUSUM) were used analyze curve. preoperative clinical baseline data, postoperative pathological...