A5073401841- Traditional Chinese Medicine Studies
- Traditional Chinese Medicine Analysis
- Liver Disease Diagnosis and Treatment
- Acupuncture Treatment Research Studies
- Liver Disease and Transplantation
- Metabolomics and Mass Spectrometry Studies
- Healthcare and Venom Research
- Pharmacological Effects of Natural Compounds
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Drug-Induced Hepatotoxicity and Protection
- Complementary and Alternative Medicine Studies
- Organ Transplantation Techniques and Outcomes
- Mitochondrial Function and Pathology
- Bone Metabolism and Diseases
- Pharmacy and Medical Practices
- Spine and Intervertebral Disc Pathology
- Helicobacter pylori-related gastroenterology studies
- Atherosclerosis and Cardiovascular Diseases
- Phytochemistry and Biological Activities
- Lipid metabolism and disorders
- Medical Research and Treatments
- Pulmonary Hypertension Research and Treatments
- Bioactive Natural Diterpenoids Research
- Pancreatitis Pathology and Treatment
Beijing University of Chinese Medicine
2009-2025
Guangzhou Medical University
2025
Tianjin Medical University
2025
Tianjin Medical University Eye Hospital
2025
Xuzhou Medical College
2025
Nanjing Drum Tower Hospital
2025
Tianjin University of Traditional Chinese Medicine
2013-2024
Children's Hospital of Fudan University
2014-2024
Wuhan City Chinese Medicine Hospital
2024
Tsinghua University
2023-2024
Ongoing inflammation in the heart is positively correlated with adverse remodeling, characterized by elevated levels of cytokines that stimulate activation cardiac fibroblasts. It was found CaMKIIδ response to Ang II or TAC triggers accumulation ROS cardiomyocytes, which subsequently stimulates NF-κB/NLRP3 and leads an increase IL-6, IL-1β, IL-18. This important causative factor occurrence remodeling failure. Sweroside a biologically active natural iridoids extracted from Lonicerae Japonicae...
Introduction /Objective. This study aimed to investigate the therapeutic efficacy of combining traditional Chinese medicine (TCM) eye-coating agents with levofloxacin in treating patients a hordeolum. Methods. Using convenience sampling, 110 hordeolum treated at Tianjin Eye Hospital between March and June 2018 were included this study. Patients randomly divided into three groups: coating group (coating + levofloxacin, n = 37), wash (eyelid 38) control (levofloxacin alone, 35). Data on nodule...
To analyze and predict the dynamic influence trends degrees caused by various factors that may affect expansion of hospital pharmacist team in China. Time series data including number visits all hospitals China, total pharmacists, per capita health expenditure, GDP from 2002 to 2022 were collected at national level. A vector autoregressive (VAR) model was constructed, methods such as Granger causality test, impulse response analysis, variance decomposition employed explore process direction...
Liver cirrhosis is a critical stage in the progression of various chronic liver diseases, often leading to severe complications such as ascites, hepatic encephalopathy, and high mortality rate, it thus poses serious threat patient life. The activation stellate cells central driver disease progression. Cellular autophagy, lysosome-mediated degradation process, plays key role maintaining cellular function dynamic homeostasis. Research has shown that autophagy closely associated with proteins...
It is clear that lipid disorder and inflammation are associated with cardiovascular diseases underlying atherosclerosis. Nur77 has been shown to be involved in inflammatory response metabolism.Here, we explored the role of atherosclerotic plaque progression apoE(-/-) mice fed a high-fat/high cholesterol diet.The gene, nuclear hormone receptor, was highly induced by treatment Cytosporone B (Csn-B, specific agonist), recombinant plasmid over-expressing (pcDNA-Nur77), while inhibited siRNAs...
Danhong injection (DHI) is the most prescribed form of Chinese medicine for treatment cardiovascular diseases such as atherosclerosis, angina pectoris, and stroke in China. However, its active components action mechanisms remain poorly defined. We hypothesized that DHI contains could prevent restore endothelial dysfunction by improving vascular relaxation activity. increased vasorelaxation vivo ex rat aortas. Vascular reactivity screen identified danshensu was major factor DHI. DHI-mediated...
Understanding how blood lipid levels change with age in the general population is a precondition to defining dyslipidemia.To explore age-related trends LDL-C and non-HDL-C population, large-scale cross-sectional study 49,201 males 35,084 females was adopted.Trends of were plotted against each (18 85 years old, one-year increments); trends, as well influence confounding factors on validated adjusted by linear regression modeling.The trajectory displayed nonlinear correlation trend.Further...
A coronary heart disease leads to increase in obesity and metabolic dysfunction. Protocatechuic acid (PCA), due its antioxidant, anti-inflammatory, neuro protective activities was found efficient as cardio-protective disease. Our study investigated hypolipidemic cardioprotective effects of protocatechuic the artery induced by high fat fructose diet (HFD) rat models. rich fed male Wistar rats prior start experimental procedures. Serum lipid levels hepatic triglycerides (TG) total cholesterol...
Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent chronic worldwide, without any Food and Drug Administration-approved pharmacological intervention in clinic. Trim38, as an important member of TRIM (tripartite motif-containing) family, was largely reported to be involved regulation innate immune inflammatory responses. However, functional roles TRIM38 NAFLD remain unknown. Here, expression first detected samples both mice model patients diagnosed with NAFLD. We found...
As the number of elderly orthodontic patients increases, impact postmenopausal osteoporosis on tooth movement (OTM) has attracted a great deal attention because OTM relies alveolar bone remodeling. The question whether causes subsequent loss and is harmful to health under osteoporotic conditions remains be answered. present study aimed clarify influences in rats. was accelerated ovariectomized (OVX) rats as result increased resorption pressure area. At same time, anabolic formation promoted...
To determine the upper cut-off values of serum alanine aminotransferase (ALT) and aspartate (AST) in a Northern Chinese population.A total 3769 subjects Jilin Province Northeast China were stratified to potential factors affecting ALT AST levels. The these determined using receiver operating characteristic analysis their sensitivity specificity evaluated.Stratification revealed that levels associated with gender, alcohol consumption, cholesterol triglyceride levels, body mass index. 22.15...
Endometritis is the inflammatory response of uterine lining which linked to infertility. Administration platelet-rich plasma (PRP) represents a well-recommended strategy for treatment endometrium-associated In this study, we set characterize role and molecular mechanism PRP intrauterine infusion in mice with endometritis.A mouse model endometritis was established using lipopolysaccharide (LPS). Mouse endometrial epithelial cells were obtained primary culture. PRP-treated assayed...
Coronary heart disease (CHD) is still the leading cause of death for adults worldwide. Traditional Chinese medicine (TCM) has a history 1000 years fighting against and provides complementary alternative treatment to it. Syndrome core TCM diagnosis it traditionally diagnosed based on macroscopic symptoms as well tongue pulse recognitions patients. Establishment method in microcosmic level an urgent major problem TCM. The aim this study was establish characteristic pattern CHD with Qi...