A5102015470- Cancer Genomics and Diagnostics
- Caching and Content Delivery
- Genetic factors in colorectal cancer
- RNA modifications and cancer
- Colorectal Cancer Treatments and Studies
- Cancer-related molecular mechanisms research
- Peer-to-Peer Network Technologies
- Cancer Immunotherapy and Biomarkers
- Opportunistic and Delay-Tolerant Networks
- Cooperative Communication and Network Coding
- Metallurgy and Material Forming
- Gastric Cancer Management and Outcomes
- Software-Defined Networks and 5G
- Genetic Mapping and Diversity in Plants and Animals
- Industrial Technology and Control Systems
- Lymphoma Diagnosis and Treatment
- RNA and protein synthesis mechanisms
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Biofuel production and bioconversion
- Colorectal Cancer Screening and Detection
- Endometrial and Cervical Cancer Treatments
- Sensorless Control of Electric Motors
- Distributed Control Multi-Agent Systems
- PARP inhibition in cancer therapy
Guangzhou Medical University
2012-2024
Second Affiliated Hospital of Guangzhou Medical University
2012-2024
North University of China
2023
Burning Rock Biotech (China)
2021-2023
University of Shanghai for Science and Technology
2021
Xiangya Hospital Central South University
2019
Central South University
2019
Southwest University
2009-2018
Huawei Technologies (United States)
2013-2016
Huawei Technologies (China)
2016
The challenging requirements of 5G, from both the applications and architecture perspectives, motivate need to explore feasibility delivering services over new network architectures. As 5G proposes application-centric slicing, which enables use data planes realizable a programmable compute, storage, transport infrastructure, we consider information- centric networking as candidate realize objectives. This can coexist with end-to-end IP that are offered today. To this effect, first propose...
Abstract Background Early detection of colorectal carcinoma (CRC) would help to identify tumors when curative treatments are available and beneficial. However, current screening methods for CRC, e.g., colonoscopy, may affect patients’ compliance due the uncomfortable, invasive time-consuming process. In recent decades, methylation profiles blood-based circulating tumor DNA (ctDNA) have shown promising results in early multiple tumors. Here we conducted a study investigate performance ctDNA...
Background: Immune checkpoint inhibitors (ICIs) have shown efficacy in patients with metastatic urothelial cancer (mUC), however, only a small subset of could benefit from ICIs. Identifying predictive biomarkers ICIs mUC is clinical meaningful for patient stratification and administration. Methods: Clinical transcriptomic data treated cohort (IMvigor210 study) was utilized to explore the biomarkers. LASSO Cox regression performed construct model. The model trained tested cohort, then...
Leukocytes play an important role in cancer development. However, the impact of chemotherapy-associated neutropenia/lymphopenia on prognosis adjuvant chemotherapy is unknown. Here, we aimed to explore neutrophil/lymphocyte counts colorectal (CRC) and risk factors for developing which showed CRC receiving chemotherapy.From February 2003 January 2011, 243 stage II III patients were enrolled this retrospective study. The associations between neutrophil/ lymphocyte disease free survival...
Purpose: The aim of this study was to evaluate the diagnostic value S100A9 and tenascin-c (TNC) levels as colorectal cancer (CRC) biomarkers in several ways, including through screening tests, differentiation combination with existing (CEA CA19-9), serum level measurements before after surgery. Materials Methods: In case-control study, TNC were measured 460 participants: 258 CRC patients, 99 patients benign colonic disease (BCD) 103 healthy donors (HD). Results: 22.32 (14.88-29.55) ng/ml,...
In this paper, we present a service-driven mobility support architecture for Information Centric Networks that provides seamless as an on-demand network service, which can be enabled/disabled based on capabilities or resource availability. Proposed relies the ID/Locator split ICN namespaces to use of persistent names and avoids name reconfiguration due mobility. We implemented proposed solution over service-centric CCN platform, with multiple end-hosts running video conferencing application...
Purpose: Tumor mutational burden (TMB) calculated by whole-exome sequencing (WES) is proved to be effective predict the clinical benefit of immune checkpoint blockades. However, WES not commonly used in China. We aimed determine if a 381-caner-gene panel (CGP) could estimate TMB, delineate landscape TMB Chinese patients and identify mutated genes pathways related higher TMB. Methods: first evaluated correlation between estimated 381-cancer-gene MasterView using data from melanoma sample...
We present a novel approach to support stateless forwarding in information centric networks with emphasis on the CCN/NDN architectures by proposing space-efficient in-packet filter based encoded counting bloom filter. Proposed solution avoids typical pitfalls of using classic Bloom Filters significantly reducing false positive transmission attempts, while supporting reliable and resource efficient delivery content packets end hosts minimal overhead. Comparisons (and filter) implementations...
Two distinct expression cassettes were synthesized by overlapping PCR for expressing the endoglucanase I gene (egl1) from Aspergillus aculeatus and II (egl2) Trichoderma reesei in a Saccharomyces cerevisiae host. One contained anchored sequence S. cwp2 gene, while other did not. The low high copy number plasmids YCplac33 YEplac195 used. enzymatic activities viscosity changes YP-CMC medium varied between eight recombinant yeast strains produced, greatest values obtained with YE-TrEII’ strain,...
Gastric cancer (GC) shows high metastasis and low survival. RNA modification writers play critical roles in tumor development. This study examined the clinical significance of GC prognosis based on four types adenosine modifications (m1A, m6A, APA A-to-I).Writers demonstrated mutation expression patients. Different expressions 26 were differentially associated with prognosis. High-WM score group appeared worse overall survival, higher immune infiltration activation EMT pathways than low-WM...
Recent studies have highlighted observations regarding re-tested positivity (RP) of SARS-CoV-2 RNA in discharged COVID-19 patients, however, the immune mechanisms underlying RP immunocompetent patients remain elusive. Herein, we describe case an patient with moderate symptoms who was twice as positive for RNA, and period between first third viral 95 days, longer than previously reported (18–25 days). The chest computed tomography findings, plasma anti-SARS-CoV-2 antibody, neutralizing...
Falls are a common risk and impose severe threats to both humans humanoid robots as product of bipedal locomotion. Inspired by human fall arrest, we present novel robot prevention strategy using arms make contact with environmental objects. Firstly, the capture point method is used detect falling. Once inevitable, arm will be actuated gain an object prevent We propose hypothesis that naturally favour select pose can generate suitable Cartesian stiffness end-effector. Based on this principle,...
Abstract ZAG2 has been identified as a maternally expressed imprinted gene in maize endosperm. Our study revealed that paternally inherited alleles were endosperm and embryo at 14 days after pollination (DAP), consistently 10, 12, 16, 18, 20, 22, 24, 26, 28 DAP reciprocal crosses between B73 Mo17. also Zheng 58 Chang 7-2 Huang C 178. exhibited differential imprinting hybrids of 178 × Huang B73 × Mo17, while other binary imprinting. The tissue-specific expression pattern showed was high level...
In this paper, we propose an overlay routing architecture for information centric networks that operates on hash-based groupings of content routers and namespaces. Proposed creates clusters within each domain using globally shared hash functions, distributes the global namespace to different clusters. doing so, achieve following notable improvements in control data plane operations: (i) reduced communication overhead setting up maintaining tables (which is resulted by hierarchical framework...
Timely accurate and cost-efficient detection of colorectal cancer (CRC) is great clinical importance. This study aims to establish prediction models for detecting CRC using plasma cell-free DNA (cfDNA) fragmentomic features. Whole-genome sequencing (WGS) was performed on cfDNA from 620 participants, including healthy individuals, patients with benign diseases patients. Using WGS data, three machine learning methods were compared build the stratification The optimal model discriminate all...
The main structures and characteristic parameters that affect the working performance of vertical spiral stirred mill were analyzed studied, a method for selecting key was proposed. Based on discrete element method, simulation model established, effects spindle speed, agitator lead grinding media size distribution analyzed. A comprehensive index proposed, orthogonal tests conducted each parameter to obtain quantitative value effect, then optimal combination under specific weight coefficient...