A5050460208- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Corneal surgery and disorders
- Retinal and Macular Surgery
- Ocular Surface and Contact Lens
- Vascular Malformations Diagnosis and Treatment
- Artificial Intelligence in Healthcare
- Digital Imaging for Blood Diseases
- Acute Ischemic Stroke Management
- Ophthalmology and Visual Impairment Studies
- Cerebrovascular and Carotid Artery Diseases
- Ubiquitin and proteasome pathways
- Atrial Fibrillation Management and Outcomes
- Inflammatory Biomarkers in Disease Prognosis
- Ophthalmology and Eye Disorders
- Cancer, Hypoxia, and Metabolism
- Cardiovascular Health and Disease Prevention
- Cell Image Analysis Techniques
- Ocular Diseases and Behçet’s Syndrome
He Eye Hospital
2019-2023
Second Affiliated Hospital of Dalian Medical University
2020
Dalian Medical University
2019-2020
Fudan University
2015
Hypertension is the leading risk factor of cardiovascular disease and has profound effects on both structure function microvasculature. Abnormalities retinal vasculature may reflect degree microvascular damage due to hypertension, these changes can be detected with fundus photographs. This study aimed use deep learning technique that detect subclinical features appearing below threshold a human observer explore effect hypertension morphological We collected 2012 photographs which included...
Medical artificial intelligence (AI) has been moving from the research phase to clinical implementation. However, most AI-based models are mainly built using high-quality images preprocessed in laboratory, which is not representative of real-world settings. This dataset bias proves a major driver AI system dysfunction. Inspired by design flow cytometry, DeepFundus, deep-learning-based fundus image classifier, developed provide automated and multidimensional sorting address this data quality...
Objective To compare the accuracy of five kinds intraocular lens calculation formulas (SRK/T, Haigis, Hoffer Q, Holladay and Barrett Universal Ⅱ) in cataract patients with steep curvature cornea ≥ 46.0 diopters. Methods This is a retrospective study phacoemulsification combined implantation (corneal 46D). The refractive prediction errors IOL power Holladay, II) using User Group for Laser Interference Biometry (ULIB) constants were evaluated compared. refraction results assessed at one month...
Aim To evaluate the association between value of neutrophil to lymphocyte ratio (NLR), platelet (PLR), monocyte high-density lipoprotein (MHR) and development retinal artery occlusion (RAO) vein (RVO). Methods This retrospective study assessed 41 RAO, 50 RVO control (age gender matched senile cataract) participants. The NLR, PLR MHR parameters patients’ peripheral blood were analyzed. A receiver operating characteristics (ROC) curve analysis best cutoff used specify predictive in RAO RVO....
To evaluate and compare the efficacy safety of YAG laser vitreolysis in treating symptomatic vitreous floaters complete posterior detachment (PVD) non-PVD. In this prospective cohort study, 51 eyes with were treated vitreolysis. Participants divided into PVD non-PVD groups. Objective visual quality measures including Strehl ratio (SR), internal spherical aberration (SA), comatic (CA), high-order (HOA), area modulation transfer function (MTFa) Vitreous Floaters Symptom Questionnaire (VFSQ-13)...
The purpose of this research was to develop protocols for evaluating the bifurcation parameters retinal arteriole and establish a reference range normal values. In retrospective study, we measured total 1314 arteriolar bifurcations from 100 fundus photographs. We selected 200 these testing inter-measurer inter-method agreement. Additionally, calculated analyzed effects gender, age, anatomical features on bifurcation. measurement method proposed in study has demonstrated nearly perfect...
To compare the effects of phacoemulsification with intraocular lens implantation (phaco) combined goniosynechialysis (phaco + GSL) versus phaco trabeculectomy trab) for management primary angle-closure glaucoma (PACG) refractory to peripheral anterior synechiae (PAS) over 180°.This retrospective study followed 77 eyes patients at least 6 months. Intraocular pressure (IOP), best-corrected visual acuity (BCVA), number drugs, and PAS were recorded preoperative baseline evaluated each...
To compare the postoperative visual acuity among eyes with proliferative diabetic retinopathy (PDR) of different stages after pars plana vitrectomy (PPV) in type 2 patients.A retrospective study was conducted for PDR undergoing PPV patients. All patients were divided into three groups based on Chinese Ocular Fundus Diseases Society (COFDS) classification PDR: Group A (primary vitreous hemorrhage), B fibrovascular proliferation) and C hemorrhage and/or combined retinal detachment). The change...
ABSTRACT Purpose The aim of this study was to use deep learning screen for hypertension and diabetes based on retinal fundus images. Methods We collected 1160 photographs which included 580 from patients with a diagnosis or normotensive non-diabetic control. divided image dataset into (i) development develop model (ii) test were not present during the training process assess model’s performance. A binary classification trained by fine-tuning classifier last convolution layer residual...
The aim of this study was to examine the relationship between morphological parameters retinal arteriolar bifurcations and coronary artery disease (CAD). In cross-sectional observational study, fundus photography conducted on 444 participants capture bifurcations. A total 731 photographs yielded 9625 measurable Analyzed bifurcation included diameters parent vessel (d0), larger branch (d1), smaller (d2), as well angles (θ1) (θ2) representing orientation each in relation vessel, respectively....
Purpose: To assess the feasibility of applying ultra-widefield fundus (UWF) images for macular staphyloma area (MSA) measurement and investigate associated factors with MSA.Methods: This is a retrospective study. MSA was measured by UWF imaging. Central foveal thickness, subfoveal choroidal scleral thickness were on spectral domain optical coherence tomography. Intraclass correlation coefficients would be evaluated. Multiple linear regression analysis used to analyze MSA.Results: In total,...
To investigate the role of deubiquitinase ubiquitin C-terminal hydrolase L1 (UCHL1) in hypertension and retinopathy spontaneously hypertensive rat (SHR).Wistar-Kyoto (WKY) rats SHRs were administered UCHL1 inhibitor LDN57444 (20 μg/kg/day) for 4 months. Pathological changes detected with hematoxylin eosin, immunofluorescence, dihydroethidium staining. The mRNA protein expression examined by real-time PCR immunoblotting analysis.At 6 months age, showed significantly increased levels retina...
Purpose: To evaluate the effect of corneal nerves assessment on predicting complications following pars plana vitrectomy (PPV).Methods: In this prospective single-center cohort study, 94 patients (94 eyes) received PPV, and were divided into postoperative groups with without complications. All eyes had nerve fiber length (CNFL), density, branch density fibers assessed calculated Image J preoperatively. Multivariate logistic regression analysis was used to identify parameters that correlated...