- Oral microbiology and periodontitis research
- MicroRNA in disease regulation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Reproductive System and Pregnancy
- Complement system in diseases
- Cancer, Lipids, and Metabolism
- Digital Imaging for Blood Diseases
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Enzyme Catalysis and Immobilization
- Carbohydrate Chemistry and Synthesis
- Tracheal and airway disorders
- Immune Response and Inflammation
- Microwave Imaging and Scattering Analysis
- Gastrointestinal motility and disorders
- Cell Image Analysis Techniques
- Immune cells in cancer
- Systemic Lupus Erythematosus Research
- Pregnancy and preeclampsia studies
- Blood groups and transfusion
- Digestive system and related health
- Congenital Diaphragmatic Hernia Studies
- Psoriasis: Treatment and Pathogenesis
Jiangxi Provincial Children's Hospital
2022-2024
Sun Yat-sen University
2023-2024
Sixth Affiliated Hospital of Sun Yat-sen University
2024
South China University of Technology
2023
Jiangxi Provincial Cancer Hospital
2023
Nanchang University
2022
Delft University of Technology
2022
Linyi People's Hospital
2019-2020
First Hospital of Lanzhou University
2017
Lanzhou University
2017
Medical artificial intelligence (AI) has been moving from the research phase to clinical implementation. However, most AI-based models are mainly built using high-quality images preprocessed in laboratory, which is not representative of real-world settings. This dataset bias proves a major driver AI system dysfunction. Inspired by design flow cytometry, DeepFundus, deep-learning-based fundus image classifier, developed provide automated and multidimensional sorting address this data quality...
Abstract A sensitive and feasible multiplexed immunoassay protocol for simultaneous electrochemical determination of carcinoembryonic antigen (CEA) alpha‐fetoprotein (AFP) was developed using multifunctionalized graphene nanotags on a cyclodextrin‐modified immunosensor. The sensor fabricated via the guest–host chemistry between immobilized cyclodextrin anti‐CEA/anti‐AFP antibodies. Two including cyclodextrin‐thionine‐graphene cyclodextrin‐ferrocene‐graphene nanostructures were synthesized...
Human activities classification in assisted living is one of the emerging applications radar. The conventional analysis considers micro-Doppler signatures as chosen input for feature extraction or deep learning algorithms, or, less frequently, other radar data formats such range-time, range-Doppler, Cadence Velocity Diagram. However, these are typically used real-valued images, whereas they actually complex-valued structures. In this paper, neural networks processing complex structures...
We, the Editors and Publisher of journal Artificial Cells, Nanomedicine, Biotechnology, have retracted following article:Shuyu Jia, Ximei Yang, Xirong Yang & Fei Zhang. (2020). MicroRNA-210 protects against periodontitis through targeting HIF-3α inhibiting p38MAPK/NF-κB pathway. 48(1), 129–136, DOI: 10.1080/21691401.2019.1699818Since publication, concerns been raised about integrity data in article. When approached for an explanation, authors unable to provide their original data. The agreed...
We sought to compare the characteristics and clinical significance of neutrophil extracellular traps in gingival samples from patients with periodontitis those gingivitis. The indexes gingivitis were measured; expression TNF-alpha IL-8 was measured by real-time fluorescent quantitative PCR; TLR-8 MMP-9 western blotting assays. Chemotaxis, phagocytosis phagocytic activity neutrophils measured. Compared healthy group, TNF-α group increased significantly (p < 0.05), lower than that 0.05)....
Heterogeneous ribonucleoprotein A1 (hnRNPA1) has been reported to enhance the Warburg effect and promote colon cancer (CC) cell proliferation, but role mechanism of miR-490-3p/hnRNPA1-b/PKM2 axis in CC have not yet elucidated.
Introduction Pregnancy outcomes of patients with systemic lupus erythematosus (SLE) have improved over the past four decades, leading to an increased desire for pregnancy among this cohort. However, offspring SLE still face risks preterm birth, low birth weight, learning disabilities, and neurological disorders, while causes underlying these remain unclear. Methods In study, we analyzed blood metabolic features neonates born 30 52 healthy control mothers by employing tandem mass spectrometry...
Congenital esophageal atresia (EA) is an abnormality induced by the incomplete differentiation of foregut in infants, and frequently accompanied tracheoesophageal fistula (TEF). Our understanding pathogenesis EA-TEF limited, additionally, there still a lack standard animal or cell models for vitro investigation. Therefore, we analyzed tissue samples from 10 children with via Exome sequencing (ES) to identify gene variants. And organoid units (EOUs) were established as model EA culturing...
Abstract Background Heterogeneous ribonucleoprotein A1 (hnRNPA1) has been reported to enhance Warburg effect and promote colon cancer (CC) proliferation, but the role mechanism of miR-490-3p/hnRNPA1-b/PKM2 axis in CC are not yet elucidated. Methods Paraffin-embedded pathological sections from 220 patients were collected subjected immunohistochemical analysis determine expression hnRNPA1-b. The relationship between values clinicopathological features was investigated. Differences mRNA...
Nervonic acid (NA) is a monounsaturated fatty vital for brain health and of emerging importance in various industrial applications, including therapeutics, food, cosmetics. Given the growing demands food pharmaceutical industries, there's pressing need high-purity NA. Previously, NA constituents plant seed oils were chemically transformed into nervonic ethyl ester (NAEE) to facilitate extraction from oils. In this study, we present an enzymatic approach convert Malania oleifera oil NAEE....
Abstract Background: We sought to compare the characteristics and clinical significance of extracellular traps neutrophils in gingival samples periodontitis gingivitis. Methods: The indexes from gingivitis were measured; expression TNF-alpha IL-8 measured by real-time fluorescent quantitative PCR; TLR-8 MMP-9 Western blotting assays Chemotaxis, phagocytosis phagocytic activity measured. Results: periodontal significantly higher than those healthy people (P<0.05). There significant...
To re-evaluate the prognostic value of absolute lymphocyte count (ALC) in pediatric immune thrombocytopenia (ITP) from perspective age. A total 242 ITP patients, including 141 newly diagnosed (nITP), 89 chronic (cITP), and 12 persistent ITP, were retrospectively reviewed for this study. These patients divided into 3 groups according to age (group 1, ≤24 m; group 2, 24-72 3, >72 m). The ALC detected at admission was significantly different between nITP cITP without considering their...