A5032132495- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Clinical Laboratory Practices and Quality Control
- Vitamin D Research Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Renal function and acid-base balance
- Urinary Tract Infections Management
- Diabetes Management and Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Metabolomics and Mass Spectrometry Studies
- Cardiovascular Function and Risk Factors
- Meta-analysis and systematic reviews
- Blood transfusion and management
- Maternal and fetal healthcare
- Acute Myocardial Infarction Research
- Blood groups and transfusion
- Iron Metabolism and Disorders
- Heart Failure Treatment and Management
- Hemoglobinopathies and Related Disorders
- Sepsis Diagnosis and Treatment
- Congenital heart defects research
- Phytochemistry and biological activities of Ficus species
- Intravenous Infusion Technology and Safety
- Medication Adherence and Compliance
- Healthcare Technology and Patient Monitoring
Siriraj Hospital
2013-2024
Mahidol University
2014-2024
Center Point
2022
University of California, Davis
2022
University of Washington
2013
Dental pulp stem cells (DPSCs) are shown to reside within the tooth and play an important role in dentin regeneration. DPSCs were first isolated characterized from human teeth most studies have focused on using this adult cell for clinical applications. However, mouse not been well their origin(s) yet elucidated. Herein we examined if murine neural crest derived determined vitro vivo capacity. neonatal expressed embryonic related genes, but lacked expression of mesodermal genes. Cells...
Abstract The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Committee on Point-of-Care Testing (C-POCT) supports the use point-of-care testing (POCT) outside hospital setting performed by healthcare professionals without formal laboratory education because its numerous benefits. However, these benefits are associated with risks that must be managed, to ensure provision reliable test results minimize harm patient. Healthcare professionals, local regulatory...
Background There are few data focusing on the prevalence of vitamin D deficiency in tropical countries. Objectives We determined status pregnant women and examined factors associated with deficiency. Design Methods A cross-sectional study 147 Thai aged 18–45 years at Siriraj Hospital (a university hospital Bangkok, Thailand) was undertaken. Clinical plasma levels 25-hydroxyvitamin [25(OH)D], intact parathyroid hormone (iPTH), calcium, albumin, phosphate magnesium were obtained delivery....
higher prevalence of hypovitaminosis D in asthmatics than the normal population; addition, low vitamin levels are associated with a severity asthma and impaired pulmonary function. 5,6Patients deficiency have shown to increased airway hyper-responsiveness corticosteroid requirements.Vitamin might increase response glucocorticoid asthmatic patients. 7,8In pregnancy, maternal intake has an inverse correlation risk recurrent wheezing childhood. 9he problems deficiency/insufficiency in-
Abstract Introduction Recently, an expert consensus on optimal use of procalcitonin (PCT)-guided antibiotic stewardship was published focusing mainly Europe and the United States. However, for Asia-Pacific countries, recommendations may need adaptation due to differences in types infections, available resources standard clinical care. Methods Practical experience with PCT-guided discussed among experts from different reflecting applicability proposed Berlin algorithms Asia-Pacific. Using a...
Context.—Each laboratory should have criteria for manual smear review that limit workload without affecting patient care. The International Consensus Group Hematology Review established guidelines action after automated blood cell analysis in 2005. Objective.—To compare the consensus group with our and optimize them better efficiency. Design.—A total of 2114 first-time samples were collected consecutively from daily used to 2 as well establish optimized criteria. Another set 891 was validate...
Objective: To evaluate and compare the performances of automated urinalysis devices UX-2000 Cobas 6500. Method: A total 258 urine specimens were collected from routine specimen workload. We analyzed all on both instruments recorded turnaround time each method. Physical, chemical, sedimentary components compared between manual method for analyzer. Results: The correlation physical/chemical properties 2 was excellent. 6500 instrument demonstrated a higher level agreement red blood cells (Cobas...
Recently, there was a new recommendation of ultrasonographic criteria to diagnosis polycystic ovary syndrome (PCOS). In addition, serum anti-Müllerian hormone (AMH) proposed as surrogate marker for PCOS, but AMH cut-off level PCOS is unclear. This study aimed investigate the accuracy and evaluate criteria, follicle number per (FNPO) threshold ≥ 25 follicles ovarian volume (OV) > 10 mL, PCOS. A cross-sectional conducted. Fifty-five women sixty-three normal ovulatory, non-hyperandrogenic were...
Isolation and ex vivo expansion of cardiac endothelial cells have been a recurrent challenge due to difficulties in isolation, cell heterogeneity, lack specific markers identify myocardial cells, inadequate conditions maintain long-term cultures. Herein, we developed method for characterization, applicable study biology clinical applications such as neoangiogenesis. First, dissociated the from murine heart by mechanical disaggregation enzymatic digestion. Then, used flow cytometry coupled...
There are limited data regarding the prevalence and risk factors relating to hypovitaminosis D in children of Thailand, a tropical country with abundant sunlight. The objective this study was assess examine associated school-aged Bangkok, Thailand – centrally located capital city. This cross-sectional evaluated 159 healthy (33.3% boys 66.7% girls), aged 6 12 years, (located at 13.45°N). Fasting plasma samples were examined for total 25-hydroxyvitamin [25(OH)D] using electrochemiluminescence...
Background: Hospitals in tropical countries experience conditions that exceed manufacturer temperature and humidity limits for point-of-care (POC) glucose reagents. Our goal was to assess the effects of out-of-limits storage temperature, operating on POC measurement reliability. Methods: Quality control measurements were performed monthly using test strips stored under controlled inpatient wards ambient conditions. Glucose evaluated groups organized by temperatures 24-25 (group 1), 28-29 2),...
Stems of Ficus hispida L. have long been prescribed as one of the constituents in various Thai traditional remedies for cancer therapy. In present study, crude ethanol extract and its sequential fractions from F. hispida L.: water, methanol: methanol ethyl acetate fraction were tested in vitro against SKBR3, MDA-MB435, MCF7 T47D human breast cell lines. The results shown that exhibited antineoplastic activity against cells. cytotoxic was further examined by MTT assay with more dilution,...
The TIMI risk score is a clinical scoring system used to predict mortality in patients following an acute coronary syndrome (ACS). B-type natriuretic peptide (BNP) has also been found be useful this setting.80 (35 men, 45 women) mean (SD) age 70.68 (9.90) years with ACS were studied. Blood was drawn within 12 hours after the onset of and blood level BNP measured using Biosite Triage Cardioprofiler Panel (Biosite Inc., San Diego, CA, USA). Patient's recorded stratified into low (0 - 2),...
Abstract Introduction: Circulating soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) are potential markers for preeclampsia. The objective was to construct analyse the reference ranges of serum levels sFlt-1 PlGF throughout course pregnancy in low-risk Thai pregnant women. Methods: We enrolled 110 low-risk, women singleton from 10 40 gestational weeks. Serum concentrations were measured with an automated assay. sFlt-1, sFlt-1/PlGF ratio constructed assessed...
Data on first-trimester circulating soluble fms-like tyrosine kinase-1 (sFlt-1) and ischemic placental disease is limited conflicting. This study aimed to its physiology in relation trophoblastic mass as the source of production.Low-risk (representing normal placentation) women from 11 0/7 13 6/7 weeks' gestation were prospectively enrolled. Selective measurement serum free sFlt-1 using a new automated assay 100 eligible subjects was analyzed with gestational age, maternal weight, fetal...
Abstract Background In 2014, the Department of Clinical Pathology, Faculty Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand developed and implemented a new process that uses fully automated instrumentation, lean management approach, autoverification to improve productivity efficiency urinalysis workflow process. The aim this study was evaluate analytical turnaround time compared with our old launched in 2014. Methods This performed at Central Laboratory center during June...
Busadee Pratumvinit, M.D., Kanit Reesukumal, Sithikan Hanyongyuth, B.P.H., Sujitra Wangchaijaroenkit, B.Sc., Julaporn Pooliam, M.Sc., Gerald J. Kost, M.D. Ph.D, Panumas Kamkang, and Tze Ping Loh, M.D.. Ann Lab Med 2019;39:209-13. https://doi.org/10.3343/alm.2019.39.2.209
In limited-resource settings, prediabetes and diabetes care demand efficient Spatial Care Paths effective geospatial optimization of medical services upstream to avoid the economic penalties untold patient complications downstream. Clever HbA1c technologies placed at leading edge primary in health small-world networks will improve where multifactorial impediments are identified by facilitation thresholds. We illustrate how formulate thresholds then actuate changes that solve problems...
Introduction: To define the effects of maternal factors, mean arterial pressure (MAP), placental volume (PV), and uterine artery Doppler pulsatility index (UtAPI) to serum level free form growth factor isoform 1 (free PlGF-1) measured with a novel automated assay.Methods: We enrolled 200 Thai women singleton pregnancy from 11+0 13+6 weeks gestation low prior risk factors (age, parity, tobacco use, assisted reproductive technology, body mass index). MAP was measured. Serum-free PlGF-1, PV,...
Thunbergia laurifolia (TL) is a commonly used herbal medicine in Thailand and other Asian countries. TL has been approved as Thai traditional for detoxifying poisons, the list of possible adverse effects includes hypoglycemia. showed hypoglycemic effect animals possibly due to antioxidant beta-cell preservation. However, safety tea its on glucose homeostasis have never investigated humans.Twenty healthy volunteers (10 men 10 women) drank 3 times/day 2 weeks. Ten subjects took 9 grams daily....