Ruth O’Kelly

ORCID: 0000-0002-8088-0241
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Gestational Diabetes Research and Management
  • Clinical Laboratory Practices and Quality Control
  • Birth, Development, and Health
  • Pregnancy and preeclampsia studies
  • Bariatric Surgery and Outcomes
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Diabetes Management and Research
  • Cardiovascular Conditions and Treatments
  • Cancer Risks and Factors
  • Meta-analysis and systematic reviews
  • Congenital Heart Disease Studies
  • Sepsis Diagnosis and Treatment
  • Cardiac Arrhythmias and Treatments
  • Statistical Methods in Clinical Trials
  • Quality and Safety in Healthcare
  • Reliability and Agreement in Measurement
  • Biotin and Related Studies
  • Thyroid Disorders and Treatments
  • Biochemical and Structural Characterization
  • Vitamin K Research Studies
  • Ethics in Clinical Research
  • Mechanical Circulatory Support Devices
  • Neonatal and Maternal Infections
  • Hormonal Regulation and Hypertension
  • Hemodynamic Monitoring and Therapy

Walter de Gruyter (Germany)
2022

Azienda Ospedaliera di Padova
2022

University of Padua
2022

Coombe Women & Infants University Hospital
2011-2021

Trinity College Dublin
2020

University College Dublin
1983

St. Vincent's University Hospital
1983

St. Vincent's Birmingham
1982

St. Vincent's Hospital
1982

St Vincent's Hospital
1982

Abstract The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Committee on Point-of-Care Testing (C-POCT) supports the use point-of-care testing (POCT) outside hospital setting performed by healthcare professionals without formal laboratory education because its numerous benefits. However, these benefits are associated with risks that must be managed, to ensure provision reliable test results minimize harm patient. Healthcare professionals, local regulatory...

10.1515/cclm-2023-0502 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 2023-06-02

To evaluate whether an intensive, medically supervised exercise intervention improved maternal glycemia and gestational weight gain in obese pregnant women when compared with routine prenatal care.This randomized controlled trial a care. The primary outcome was reduction mean fasting plasma glucose the group by 6.9 mg/dL at time of 75-g oral tolerance test 24-28 weeks gestation. Secondary outcomes included excessive gain. consisted 50-60 minutes exercise: warm-up, resistance or weights,...

10.1097/aog.0000000000002267 article EN Obstetrics and Gynecology 2017-10-10

Abstract Clinicians trust medical laboratories to provide reliable results on which they rely for clinical decisions. Laboratories fulfil their responsibility accurate and consistent by utilizing an arsenal of approaches, ranging from validation verification experiments daily quality control procedures. All these procedures verify, different moments, that the a certain examination procedure have analytical performance characteristics (APC) meet specifications (APS) set particular intended...

10.1515/cclm-2022-0083 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 2022-02-16

While heparin-induced aldosterone deficiency has been sporadically reported,it is not known whether heparin always inhibits production to a variable extent or if this an idiosyncratic effect, nor the mechanism underlying phenomenon known. We have examined plasma aldosterone, PRA, and renin activity ratiosin 20 patients before, during after treatment with heparin. Aldosterone fell from 73.5 ± 20.5 36.8 11.2 pg/ml (P < 0.05) rose its withdrawal 94.8 37.1 0.05). PRA 2.8 1.0 6.1 1.6 ng/ml-h 2.4...

10.1210/jcem-56-1-108 article EN The Journal of Clinical Endocrinology & Metabolism 1983-01-01

Abstract Background Point-of-care (POC) measurement of glucose is currently recommended only for the monitoring gestational diabetes mellitus (GDM). This prospective observational study evaluated use POC measurements maternal to diagnose GDM in women being screened selectively with a 1-step 75 g oral tolerance test (OGTT). Methods The strictest preanalytic and analytic international laboratory standards were applied measure plasma at fasting 1 2 h post load. recent International Association...

10.1093/clinchem/hvz005 article EN Clinical Chemistry 2020-01-30

Background The inhibition of glycolysis prior to glucose measurement is an important consideration when interpreting tolerance tests. This particularly in gestational diabetes mellitus where prompt diagnosis and treatment essential. A study was planned investigate the effect preservatives temperature on glycolysis. Methods Blood samples for were obtained from consented females. Lithium heparin fluoride-EDTA transported rapidly ice slurry laboratory analysed concentration then held either or...

10.1177/0004563216682978 article EN Annals of Clinical Biochemistry International Journal of Laboratory Medicine 2017-01-13

Human papillomavirus (HPV) is considered the strongest epidemiologic risk factor for cervical cancer. However, it not a sufficient cause given high prevalence of transient infections. We examined relationship between exposure to tobacco smoke, measured using urinary nicotine metabolite concentrations, and p16/Ki-67 co-expression in smears subsequent developing CIN2+/CIN3+ lesions HPV positive women.This prospective longitudinal study enrolled women presenting colposcopy with cytological...

10.1016/j.canep.2020.101793 article EN cc-by Cancer Epidemiology 2020-08-22

A cooperative study involving 296 pigs was conducted at two experiment stations and a commercial research farm to evaluate the efficacy of nosiheptide as growth promotant for growing-finishing swine. At each station, five or six replicate pens four pigs/pen were fed fortified, corn-soybean meal basal diet with 0, 5.5, 11 22 ppm nosiheptide. Initial final weights averaged 92 kg, respectively. Daily gain increased quadratically (623, 664, 669, 678 g/d; P<.03) feed/gain decreased (3.35, 3.24,...

10.2527/jas1984.5951125x article EN Journal of Animal Science 1984-11-01

Objective: To examine the correlation between spot urine PCR and 24-hour protein excretion in patients being evaluated for preeclampsia. Population or sample: 98 pregnant women with suspected preeclampsia a gestational age more than 20 weeks. Methods: A random sample was collected immediately before after collection. The creatinine ratio calculated by dividing urinary concentration concentration, assessed. Results: at cut-off value of 0.02 g/mmol (0.18 g/g) had sensitivity specificity...

10.35841/2591-7366.17.1.12 article EN Research and Reports in Gynecology and Obstetrics 2018-01-01

Large-for-gestational-age (LGA) is associated with both fetal and maternal complications. One of the few modifiable risk factors for LGA Gestational Diabetes Mellitus (GDM); this reason, growth usually monitored by ultrasound in third trimester. This prospective study compared a panel ten established biomarkers measured at time selective screening GDM 26-28 weeks gestation prediction LGA.Women were recruited using convenience sampling consented first antenatal visit. Women attended one-step...

10.1080/14767058.2021.1911993 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2021-04-28

Fazit Bei sehr kleinen Frühgeborenen zeigen sich deutliche Korrelationen der Plasmakonzentration von NT-proBNP mit dem Vorhandensein eines offenen Ductus arteriosus und dessen Durchmesser bis zur 3. Lebenswoche. Das Fehlen einer solchen Korrelation nach Tag 21 liegt möglicherweise auch daran, dass die Zahl Kinder offenem danach immer weiter abnahm. Der Laborwert könnte eventuell als Ergänzung oder Alternative Echokardiografie eingesetzt werden, wenn diese nicht durchführbar ist. Weitere...

10.1055/s-0034-1392174 article DE Neonatologie Scan 2015-06-11

To determine if routine ultrasound for fetal growth in the third trimester could identify fetuses with intrauterine restriction associated maternal smoking pregnancy. A prospective study recruited women who were (n = 71) and not pregnancy 72). Caucasian ultrasonographic determination of gestational age ≤ 14 weeks gestation eligible. Exclusion criteria recreational drug use, multiple pregnancy, insulin dependent diabetes, development < 18 or > 40 years. Serial ultrasounds performed at 28, 32,...

10.1002/uog.5759 article EN Ultrasound in Obstetrics and Gynecology 2008-08-01
Coming Soon ...