Abstract Small extracellular vesicles (sEVs)-derived circular RNAs (circRNAs) could regulate gene expression in recipient cells, and dysregulation of sEVs-derived circRNAs has been implicated several diseases. However, the function coronary heart atherosclerotic disease (CAD) remain unknown. In this study, we investigated global changes patterns sEVs from CAD-related monocytes identified circNPHP4 as a significantly upregulated circRNA. Knockdown inhibited heterogeneous adhesion between...

Early diagnosis and treatment significantly improve the prognosis of coronary heart disease (CHD), but no convenient screening tools are available. This study aims to find potential non-invasive biomarkers disease.We performed microarray analysis investigate mRNA expression levels in Small extracellular vesicles (sEVs) screen differentially expressed mRNAs CHD patients vs. non-CHD patients. We then quantitative real-time polymerase chain reaction (qRT-PCR) validate results, we calculated...

Abstract Heart failure (HF), with its high morbidity and mortality, remains a global public health issue. Right ventricular (RV) dysfunction is sign of deterioration in the natural history HF, thorough evaluation relationship between RV contractility afterload through RV–pulmonary arterial (RV–PA) coupling can aid accurately assessing overall function. The ratio end‐systolic elastance (Ees) to pulmonary (Ea) invasively measured by right heart catheterization served as gold standard for...

Left atrial reservoir strain (LARS) is a novel imaging biomarker of left ventricular diastolic dysfunction. This study aimed to examine the prognostic implications LARS in patients with bicuspid aortic valve and significant (moderate-severe severe) regurgitation.

Abstract Background Tissue motion of mitral annular displacement (TMAD) assessment has proved to be an effective method for several cardiovascular diseases including hypertrophic cardiomyopathy, heart failure, non‐ST‐elevation myocardial infarction, etc. However, there are no studies exploring the feasibility TMAD in transplantation (HT) recipients, and predictive value this parameter adverse outcomes these patients remains unknown. Consequently, study aimed evaluate evaluation left...

Abstract Background Due to insufficient near‐field resolution and artifacts, it is challenging evaluate the left ventricular apical perfusion with phased‐array probes. By combining high‐frequency linear probe contrast‐enhanced ultrasound (CEUS), imaging of myocardial could be improved. The study aims preliminary application CEUS by probes assess perfusion. Methods enrolled retrospectively 91 patients test feasibility novel method. In protocol 1, were stratified into a group anterior...

Abstract This case study demonstrates the feasibility of pacing left bundle branch and atrial septum under transthoracic echocardiography (TTE) without fluoroscopic guidance. technique could be useful to guide pacemaker implantation in some patients, especially pregnant women.

Journal Article Corrected proof Utilizing multimodal imaging for diagnosing a complex apical aneurysm Get access Ruohan Zhao, Zhao Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University Science and Technology, Wuhan 430022, ChinaHubei Province Clinical Research Center Imaging, Key Laboratory Molecular China Search other works by this author on: Oxford Academic PubMed Google Scholar Wenqian Wu, Wu Xin Chen, Chen Mingxing Xie, Xie Corresponding author....

To the Editor: Echocardiography is a valuable tool for diagnosing and predicting cardiovascular disease; however, it has certain limitations, such as being operator-dependent having complex multidimensional nature that can make interpretation challenging. Artificial intelligence (AI) adept at analyzing processing large, complex, data. It automatically analyze integrate information from multiple sources to build prediction models. This increase efficiency of echocardiography in healthcare,...

Abstract Aim To evaluate ventricular synchronization and function in patients with right bundle-branch block after left bundle-branch-area pacing (LBBAP) by echocardiography. Methods Forty who successfully received LBBAP were selected divided into the group (RBBB group) non-RBBB pre-operation ECG. Echocardiography follow-up performed 1 month operation. Interventricular was evaluated tissue Doppler (TDI), mitral annular displacement (TMAD), interventricular mechanical delay. The tricuspid...

Abstract Background : Long noncoding RNAs (lncRNAs) are involved in many physiological processes and have also been reported to play an essential role cardiovascular diseases. However, lncRNAs not used as a serological marker diagnose coronary artery disease (CAD) clinics. Methods We employed lncRNA microarray analyse expression monocyte small extracellular vesicles (sEVs) from three CAD patients healthy controls. validated the differential of both plasma sEVs by quantitative real-time PCR...

Figure 1 (A) Transthoracic echocardiography revealed enlarged right heart chambers with moderate tricuspid regurgitation, and the velocity of regurgitation.(B) The suprasternal axis view showed an abnormal laminar continuous venous flow draining into LIV.(C ) TEE a PFO.Colour Doppler left-right shunting, right-heart agitated saline study shown immediate passage bubbles from RA to LA through PFO.(D) colour Cooper, negative contrast two separate bloodstreams that drained SVC.(E) A...

Noninvasive left ventricular pressure-strain myocardial work (MW) is a novel method for evaluating function that integrates deformation and afterload has certain advantages over global longitudinal strain (GLS). The study aimed to analyze MW in patients with well-functioning bicuspid aortic valve (BAV) explore the influences of dilation arterial stiffness on function.A total 104 BAVs 50 controls were enrolled our study. Global index (GWI), constructive (GCW), wasted (GWW), efficiency (GWE),...

Abstract Background Long noncoding RNAs (lncRNAs) constitute integral components of many physiological processes and exhibit considerable impact on cardiovascular maladies. Nonetheless, the clinical utilization lncRNAs as serological markers for diagnosing Coronary Artery Disease (CAD) remains unexplored. Methods To scrutinize lncRNA expression, we harnessed a microarray to probe monocyte small extracellular vesicles (sEVs) derived from three CAD patients an equivalent number healthy...

The power grid is one of the largest and most complex interconnected systems. It a typical research object cyber physical characteristics systems are their abilities to improve overall performance system optimize operation through more advanced control methods with stronger safety reliability. Most terminals in embedded terminals. Not only must they have conventional information interaction capabilities, but also meet real-time requirements measurement under resource constraints. large need...

Abstract Endocardial radiofrequency ablation of the septal hypertrophy (ERASH) is an alternative for hypertrophic obstructive cardiomyopathy (HOCM). Radiofrequency could lead to regional myocardial akinesia, so as relieve left ventricular outflow tract (LVOT) gradient. We reported that two patients presented Left asymmetric in transthoracic echocardiography, and were diagnosed with HOCM. One had a gradient up 210mmHg during provocation. The other LVOT 108mmHg at rest. Both are symptomatic...

Abstract AimTo evaluate ventricular synchronization and function in patients with right bundle-branch block after left bundle-branch-area pacing (LBBAP) by echocardiography.MethodsForty who successfully received LBBAP were selected divided into the group (RBBB group) non-RBBB pre-operation ECG. Echocardiography follow-up performed 1 month operation. Interventricular was evaluated tissue Doppler (TDI), mitral annular displacement (TMAD), interventricular mechanical delay (IVMD). The tricuspid...

Aim To evaluate ventricular synchronization and function in patients with right bundle-branch block after left bundle-branch-area pacing (LBBAP) by echocardiography. Methods Forty who successfully received LBBAP were selected divided into the group (RBBB group) non-RBBB pre-operation ECG. Echocardiography follow-up performed 1 month operation. Interventricular was evaluated tissue Doppler (TDI), mitral annular displacement (TMAD), interventricular mechanical delay (IVMD). The longitudinal...

Extramedullary involvement of the endocardium is rare in multiple myeloma. Here we describe a case myeloma (plasma cell) with extramedullary plasmablastic transformation and endocardial involvement, which resulted partial superior vena cava obstruction. We also conducted literature review summary analysis space-occupying lesions heart 12 patients (including current case) last 10 years. Echocardiography preferred radiologic examination method for diagnosis follow-up myeloma, surgical...