A5083481622- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Essential Oils and Antimicrobial Activity
- Oral Health Pathology and Treatment
- Coconut Research and Applications
- Drug Solubulity and Delivery Systems
- Oral and Maxillofacial Pathology
- Bee Products Chemical Analysis
- Innovations in Medical Education
- RNA Interference and Gene Delivery
- Peptidase Inhibition and Analysis
- Drug-Induced Hepatotoxicity and Protection
- Drug Transport and Resistance Mechanisms
- Oral and gingival health research
- Antimicrobial Peptides and Activities
- Empathy and Medical Education
- Nanoparticle-Based Drug Delivery
- Antifungal resistance and susceptibility
- Food Chemistry and Fat Analysis
- Learning Styles and Cognitive Differences
- Proteins in Food Systems
- Oral and Craniofacial Lesions
- Enzyme Production and Characterization
- Microencapsulation and Drying Processes
- SARS-CoV-2 and COVID-19 Research
King Abdulaziz University
2014-2024
University of Jeddah
2021
Faculty (United Kingdom)
2021
American Dental Education Association
2020
John Wiley & Sons (United States)
2020
The graphene family of nanomaterials acquired significant attention in the field dentistry due to a range interesting properties. Graphene oxide (GO) and reduced (rGO) are major derivatives that widely used dental applications. These exhibit excellent mechanical properties, superior biocompatibility, good antibacterial extreme chemical stability, favorable tribological characteristics, thus representing highly materials for dentistry. amphiphilic nature GO allows covalent noncovalent...
Abstract This study explores the utilization of Spent Coffee Grounds (SCG), a residual product coffee industry, as microfiller reinforcement in Poly‐3‐hydroxybutyrate‐co‐3‐hydroxyvalerate (PHBV) biopolymer composites at varying concentrations (1%, 3%, 5%, and 7%). Melt compounding via twin‐screw extruder subsequent compression molding were employed fabrication process. The SCG microfiller, with particle diameters ranging from 1.11 to 1.28 μm, exhibited significant negative charge (zeta...
Drug administration to the wound site is a potential method for healing. The drug retention duration should be extended, and permeability through buccal mucosal layer regulated. Oral wounds can caused by inflammation, ulcers, trauma, or pathological lesions; if these are not treated properly, they lead pain, infection, subsequent undesirable scarring. This study aimed develop Kolliphor-407 P-based gel containing neomycin sulfate (NES) loaded in solid lipid nanoparticles (SLNs) enhance...
COVID-19, caused by SARS-CoV-2, has impacted the world in an unprecedented way since December 2019. SARS-CoV-2 was found saliva of patients, and entry points for virus may have been through numerous angiotensin-converting enzyme 2 receptors oral cavity. Oral manifestations COVID-19 could contribute to burden disease.To determine prevalence patients their association with disease severity.Interviews were conducted adult participants diagnosed between October 2021 March 2022 document...
Burn wound healing is a complex process that involves the repair of injured tissues and control infection to diminish scar formation, pain, discomfort associated with such injuries. The aim this research was formulate optimize self-nanoemulsion drug delivery system based on use coconut oil loaded simvastatin. Coconut possesses antiinflammatory antibacterial activity, simvastatin has interesting properties for promoting wound-healing because it increases production vascular endothelial growth...
Herpes labialis, caused by herpes simplex virus type 1, is usually characterized painful skin or mucosal lesions. Penciclovir (PV) tablets are found to be effective against labialis but suffer from poor oral bioavailability. This study aimed combine the benefits of PV and lavender oil (LO), which exhibits anesthetic activity, in form a self-nanoemulsifying drug delivery system (SNEDDS) for treatment labialis. Toward this purpose, LO (oil), Labrasol:Labrafil M1944 CS ratio 6:4 (surfactant...
The goal of the current study is to develop a chitosan alginate nanoparticle system encapsulating model drug, simvastatin (SIM-CA-NP) using novel polyelectrolytic complexation method. formulation was optimized central composite design by considering concentrations and at five different levels (coded as +1.414, +1, 0, -1, -1.414) in achieving minimum particle size (PS-Y1) maximum entrapment efficiency (EE-Y2). A total 13 runs were formulated (as projected Design-Expert software) evaluated...
Candida albicans is the fungus responsible for oral candidiasis, a prevalent disease. The development of antifungal-based delivery systems has always been major challenge researchers. This study was designed to develop nanostructured lipid carrier (NLC) sesame oil (SO) loaded with miconazole (MZ) that could overcome solubility problems MZ and enhance its antifungal activity against candidiasis. In formulation this study, SO used as component liquid showed an improved effect MZ. An optimized...
The majority of newly developed drugs need to be incorporated with delivery systems maximize their effect and minimize side effects. Nanoemulsions (NEs) are one type system that helps improve the solubility dissolution drugs, attempting enhance bioavailability onset action. objective this investigation was develop an omega-3 oil-based NE loaded loxoprofen (LXP) its dissolution, in vitro release, mucosal penetration decrease ulcerative effects when applied oral treatment. LXP-loaded NEs were...
Oral health is a key contributor to person’s overall and well-being. microbiota can pose serious threat oral health. Thus, the present study aimed develop cinnamon oil (CO)-loaded nanoemulsion gel (NEG1) enhance solubilization of within cavity, which will its antibacterial, antifungal, analgesic actions against microbiota. For this purpose, CO-loaded (CO-NE) was optimized using I-optimal response surface design. A mixture Pluracare L44 PlurolOleique CC 497 used as surfactant Capryol...
The use of essential oil–based nanoemulsions (NEs) has been the subject extensive research on a variety conditions affecting oral cavity. NEs are delivery methods that improve solubility and distribution lipid medicines to intended areas. Because their antibacterial antifungal properties, itraconazole thyme self-nanoemulsifying drug systems (ItZ-ThO-SNEDDS) were created protect health against microorganisms. ItZ-ThO-SNEDDS utilizing an extreme verices mixture design, varying concentrations...
Numerous problems affect oral health, and intensive research is focused on essential oil-based nanoemulsions that might treat prevent or these problems. Nanoemulsions are delivery systems enhance the distribution solubility of lipid medications to targeted locations. Turmeric (Tur)- curry leaf oil (CrO)-based (CrO-Tur-self-nanoemulsifying drug [SNEDDS]) were developed with goal improving health preventing treating gingivitis. They could be valuable because their antibacterial...
Natural oil-based nanoemulsions (NEs) have been widely investigated in many diseases that affect the oral cavity. NEs are delivery systems enhance solubility of lipid therapeutics and improve their to target sites; they known as self-nanoemulsifying drug (SNEDDSs). The current investigation's aim was produce an oregano essential nanoemulsion (OEO-SNEDD) would antibacterial antifungal effects against microbiota health.Several OEO-SNEDDSs were developed using different percentages OEO (10%,...
Oral and maxillofacial lesions (OMFL) comprise a broad spectrum of benign malignant that affect the oral cavity. However, few epidemiological studies have evaluated cavity lesions, very focused on soft tissue pathology. The purpose this study was to identify prevalence distribution OMFL had been diagnosed histologically at Pathology Laboratory, Faculty Dentistry, King Abdulaziz University.A retrospective conducted assess among biopsies submitted Laboratory during period from 1996 2016....
Diagnosing oral and maxillofacial lesions is a multi-step, multidisciplinary process. If clinical diagnosis achievable, then histopathological indicated to support confirm the diagnosis. Histopathological examination of tissue biopsies therefore an essential part and/or treatment plan. The purpose this study was investigate agreement between diagnoses patient, lesion, healthcare provider factors that may affect agreement.
Empathy is the fundamental substructure of moral behavior. Skillful clinicians may not necessarily be successful dentists if they do have sufficient empathy. The aim this study was to assess level empathy among dental students at King Abdulaziz University with an emphasis on effect gender and level. A cross-sectional carried out third- sixth-year in Jeddah, Saudi Arabia. validated, self-administered Jefferson Scale Empathy-Health Care Provider Student Version distributed academic year...
Maintaining oral health helps to prevent periodontal inflammation and pain, which can progress into more detrimental issues if left untreated. Meloxicam (MX) is a commonly used analgesic for but it have adverse gastrointestinal effects poor solubility. Therefore, this study aimed enhance the solubility of MX by developing self-nanoemulsifying drug delivery system (SNEDDS). Considering anti-ulcer activity peppermint oil (PO), was added in mixture with medium-chain triglyceride (MCT) MX-loaded...