A5010892361- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Urticaria and Related Conditions
- Advanced Drug Delivery Systems
- Oral Health Pathology and Treatment
- Healthcare Systems and Technology
- Advancements in Transdermal Drug Delivery
- Proteins in Food Systems
- Salivary Gland Tumors Diagnosis and Treatment
- Coconut Research and Applications
- Dermatology and Skin Diseases
- Herpesvirus Infections and Treatments
- Cancer, Lipids, and Metabolism
- Online and Blended Learning
- Innovations in Educational Methods
- Platelet Disorders and Treatments
- Telemedicine and Telehealth Implementation
- Evaluation of Teaching Practices
- Acne and Rosacea Treatments and Effects
- Computational Drug Discovery Methods
- Ear and Head Tumors
- Protein Degradation and Inhibitors
- Legionella and Acanthamoeba research
- Antimicrobial agents and applications
- Phytochemistry and biological activity of medicinal plants
University Children's Hospital Tübingen
2025
Ain Shams University
2024
University College Hospital
2024
University College London
2011-2024
King Abdulaziz University
2015-2023
Alsalam University College
2022
Royal Alexandra Children's Hospital
2021
Royal London Hospital
2011-2021
Moorfields Eye Hospital NHS Foundation Trust
2020
Moorfields Eye Hospital
2020
Teledentistry has emerged as a new communication tool in various dental disciplines around the world. The aim of this study was to investigate applicability and reliability teledentistry field diagnostic dentistry explore perception Saudi dentists its benefits concerns.An electronic survey with 40 questions developed, validated distributed electronically by email social media channels from different specialty Arabia. Collected data were analyzed for statistical significance.A total 148...
Herpes labialis, caused by herpes simplex virus type 1, is usually characterized painful skin or mucosal lesions. Penciclovir (PV) tablets are found to be effective against labialis but suffer from poor oral bioavailability. This study aimed combine the benefits of PV and lavender oil (LO), which exhibits anesthetic activity, in form a self-nanoemulsifying drug delivery system (SNEDDS) for treatment labialis. Toward this purpose, LO (oil), Labrasol:Labrafil M1944 CS ratio 6:4 (surfactant...
The goal of the current study is to develop a chitosan alginate nanoparticle system encapsulating model drug, simvastatin (SIM-CA-NP) using novel polyelectrolytic complexation method. formulation was optimized central composite design by considering concentrations and at five different levels (coded as +1.414, +1, 0, -1, -1.414) in achieving minimum particle size (PS-Y1) maximum entrapment efficiency (EE-Y2). A total 13 runs were formulated (as projected Design-Expert software) evaluated...
Candida albicans is the fungus responsible for oral candidiasis, a prevalent disease. The development of antifungal-based delivery systems has always been major challenge researchers. This study was designed to develop nanostructured lipid carrier (NLC) sesame oil (SO) loaded with miconazole (MZ) that could overcome solubility problems MZ and enhance its antifungal activity against candidiasis. In formulation this study, SO used as component liquid showed an improved effect MZ. An optimized...
Mucous membrane pemphigoid (MMP) is an uncommon mucocutaneous immunobullous disorder. Use of saliva for diagnosis by enzyme‐linked immunosorbent assay (ELISA) using the noncollagenous (NC) domain 16a bullous antigen II (BP180) not well described. To establish whether whole or parotid a suitable alternative to serum MMP. Precoated BP180‐NC16a ELISA plates were used test serum, and IgG, IgA secretory antibodies. Patients with MMP (n = 64) provided matched saliva. In addition 18 patients also...
The use of saliva for the diagnosis pemphigus vulgaris (PV) by enzyme-linked immunosorbent assay (ELISA) using desmoglein (Dsg)3 antigen has not been extensively documented, nor detection serum IgA antibodies to Dsg3.(i) To establish whether whole might provide a suitable alternative diagnosing and monitoring PV; (ii) investigate anti-Dsg3 can be detected in (iii) there is an association between or disease severity.Precoated Dsg3 ELISA plates were used test and/or IgG antibodies. Matched...
Natural oil-based nanoemulsions (NEs) have been widely investigated in many diseases that affect the oral cavity. NEs are delivery systems enhance solubility of lipid therapeutics and improve their to target sites; they known as self-nanoemulsifying drug (SNEDDSs). The current investigation's aim was produce an oregano essential nanoemulsion (OEO-SNEDD) would antibacterial antifungal effects against microbiota health.Several OEO-SNEDDSs were developed using different percentages OEO (10%,...
The exponentially mounting cases of herpes simplex virus infection or cold sores have become a serious global concern. Acyclovir (ACV) and garlic oil (GO)-loaded lipid nanocarrier could be promising therapeutic approach in alleviating sores, as well limiting the biopharmaceutical constraints associated with ACV absorption efficacy. Therefore, objective current research study was to formulate an ACV-GO self-nanoemulsifying drug delivery system (ACV-GO-SNEDDS) transdermal films. prepared...
Smokeless tobacco (SLT) causes significant harm to the oral cavity and is considered a risk factor for cancer. Various forms, products, patterns of SLT are used across different populations. Many such as nicotine betel nut, have addictive carcinogenic properties. use associated with benign, premalignant, or malignant lesions. This study aimed identify characteristics these lesions their association exposure.This cross-sectional study, performed at our institution's Faculty Dentistry,...
Tongue cancer is one of the most common carcinomas head and neck region. The antitumor activities statins, including lovastatin (LV), essential oil eucalyptus (Eu oil), have been adequately reported. aim this study was to develop a nanoemulgel containing LV combined with Eu that could then be made into nanoemulsion assessed determine its cytotoxicity against cell line human chondrosarcoma-3 (HSC3) carcinoma tongue. An I-optimal coordinate-exchange quadratic mixture design adopted optimize...
BACKGROUND:Multiple myeloma is a hematological malignancy characterized by monoclonal plasma cell proliferation. Jaw lesions are found in nearly 35% of patients with symptomatic myeloma, and occur the mandible more often than maxilla. However, maxillary or mandibular rarely as primary manifestation disease. This report describes case 65-year-old Palestinian woman lytic maxilla due to undiagnosed multiple identified incidentally on cone beam computed tomography (CBCT). CASE REPORT:A presented...
Abstract Background Conventional classroom lectures continue to represent a major component of the dental education system ensure optimum delivery knowledge. Certain number students are less compliant and likely skip classes which may impact overall academic performance. The aim this study was investigate students’ attitude towards attendance potential reasons for absenteeism at King Abdulaziz University-Faculty Dentistry (KAU-FD). Methods This cross-sectional survey all actively enrolled...
Oral squamous cell carcinoma (OSCC) is the most common epithelial tumor of oral cavity. Gingival tumors, a unique type OSCC, account for 10% these malignant tumors. The antineoplastic properties statins, including pitavastatin (PV), and essential oil Pinus densiflora leaf (Pd oil) have been adequately reported. goal this investigation was to develop nanostructured lipid carriers (NLCs) containing PV combined with Pd determine their cytotoxicity against line human gingival fibroblasts...
Cancer is one the most common health issues worldwide, with cancer-related mortality of 9.5 million in 2018, an expectation to become 29.5 by 2040. Among others, acute myeloid leukemia (AML) among older people. FLT3 mutations are genetic aberrations found Acute Myeloid Leukemia and associated poor prognosis. Herein, we attempt identify natural compounds as potential candidates treat AML targeting kinase domain using silico approaches. The COCONUT database, which contains 407,270 compounds,...
Based on the administration convenience, transmucosal buccal drug delivery allows special strength points over peroral routes for systemic delivery. It could achieve local or effect and boost drugs' bioavailability agents with first pass metabolism. The current study aimed to manufacture optimize a lavender oil-based nanoemulsion loaded zaleplon incorporate it into fast-disintegrating tablets promote its dissolution oral via mucosa. Zaleplon-loaded nanoemulsions were devised various levels...
Introduction: Teledentistry is an emerging tool to exchange medical information and clinical images facilitate the diagnosis, prevention, treatment of oral diseases patient assurance education. Considering shortage medicine specialists in Saudi Arabia, this study aims assess experiences dental with tele-oral its potential applicability addressing shortage. Materials methods: This was a pilot, cross-sectional conducted among field from January 2020 March 2020. A total 16 preselected cases...
Approximately 10% of pleomorphic adenomas occur in the minor salivary glands with palate being most common site. Pleomorphic account for majority palatal tumours; however, gland tumours have a higher risk malignancy compared to major glands, so appropriate diagnostic evaluation should be prompt. We present case 52-year-old man longstanding history soft adenoma which required excision under general anaesthetic via mandibular swing approach. As well as surgical approach access this tumour; is...