- Transcranial Magnetic Stimulation Studies
- Spinal Cord Injury Research
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Cardiovascular Health and Risk Factors
- Health, Environment, Cognitive Aging
- Nutritional Studies and Diet
- Liver Disease and Transplantation
- Blood Pressure and Hypertension Studies
- Stroke Rehabilitation and Recovery
- Pain Management and Treatment
- Systemic Lupus Erythematosus Research
- Virtual Reality Applications and Impacts
- Vestibular and auditory disorders
- Alcohol Consumption and Health Effects
- EEG and Brain-Computer Interfaces
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Muscle activation and electromyography studies
- Action Observation and Synchronization
- Infectious Diseases and Tuberculosis
- Cerebrovascular and Carotid Artery Diseases
- Physical Activity and Health
- Neurological Complications and Syndromes
Paracelsus Medical University
2015-2025
Weatherford College
2023
Christian Doppler Klinik
2015-2023
University Hospital of Zurich
2023
University of Zurich
2023
Institut des Sciences Cognitives Marc Jeannerod
2023
Paracelsus Medizinische Privatuniversität
2021-2022
Austrian Cluster for Tissue Regeneration
2021
University of Verona
2017
Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by systemic inflammation. While RA primarily affects the joints, its effects may lead to an increased cerebro- and cardiovascular risk. Atherosclerosis of carotid arteries significant risk factor for cerebrovascular events serves as surrogate marker This study explores link between artery atherosclerosis with data from Paracelsus 10,000 Study. Baseline assessments were conducted on individuals randomly selected Salzburg...
Individuals with lower levels of education are at a higher risk developing various health conditions due to limited access healthcare and unhealthy lifestyle choices. However, the association between non-alcoholic fatty liver disease (NAFLD) educational level remains unclear. Therefore, aim this study was investigate whether there is an independent relationship NAFLD as surrogate marker for socioeconomic status (SES).This cross-sectional included 8,727 participants from Paracelsus 10,000...
Hyperferritinemia (HF) is a common finding and can be considered as metabolic HF (MHF) in combination with diseases. The definition of MHF was heterogenous until consensus statement published recently. Our aim to apply the provide data on prevalence characteristics Central-European cohort.
Background/Aims: Paracelsus 10,000 is an observational cohort study with the objective to investigate health status of population in and around city Salzburg. The focus lies on common non-communicable diseases, mainly cardiovascular, cerebrovascular, metabolic their risk factors. aim establish a large database enabling associations between life style, genetic factors development diseases. Extensive phenotyping biobanking constitute basis for preventive measures, multi-omics precision...
Introduction: Alzheimer’s disease (AD) and aging are associated with platelet hyperactivity. However, the mechanisms underlying abnormal function in AD yet poorly understood. Methods: To explore molecular profile of aged platelets, we investigated activation (i.e., CD62P expression), proteome transcriptome patients, non-demented elderly, young individuals as controls. Results: AD, showed similar levels based on expression. had a proteomic signature suggestive increased compared...
Purpose: Spasticity is a common disorder in patients with spinal cord injury (SCI). The aim of this study was to investigate whether intermittent theta burst stimulation (iTBS), safe, non-invasive and well-tolerated protocol excitatory repetitive transcranial magnetic (rTMS), ef fective modulating spasticity SCI patients. Methods: In randomized, double-blind, crossover, sham-controlled study, ten subjects incomplete cervical or thoracic received 10 days daily sessions real sham iTBS. H/M...
Depression is the most common mental illness worldwide and generates an enormous health economic burden. Furthermore, it known to be associated with elevated risk of arteriosclerotic cardiovascular diseases (ASCVD), particularly stroke. However, not a factor reflected in many ASCVD models, including SCORE2. Thus, we analysed relationship between depression, SCORE2 our cohort.
Background The association between education and atherosclerotic cardiovascular disease (ASCVD) has been well described for decades. Nevertheless, most risk models, including SCORE2, still do not take educational status into account even if this factor is easily assessed costs nothing to acquire. Using carotid plaques as a proxy ASCVD, we analysed associated with plaque development, determine the relationship remains, how it relates traditional factors and, impacts European model, SCORE2....
Education is not a factor included in most cardiovascular risk models, including SCORE2. However, higher education has been associated with lower morbidity and mortality. Using CACS as proxy for ASCVD, we studied the association between educational status. Subjects, aged 40–69, from Paracelsus 10,000 cohort, who underwent calcium scoring part of screening subclinical were classified into low, medium, high status using Generalized International Standard Classification Education. was...
A major risk factor to develop active tuberculosis (TB) is the infection with human immunodeficiency virus (HIV). Chest radiography first-line imaging modality used rule out TB. Coinfected individuals present often atypical patterns, due immunosuppression caused by virus, making diagnosis difficult. In this prospective observational study 268 TB and HIV coinfected patients were included. During a follow-up period of 24 weeks, predominant patterns on chest analyzed compared cluster...
Synchronous visuotactile stimulation on the own hidden hand and a visible fake limb can alter bodily self-perception influence spontaneous neuroplasticity. The rubber illusion (RHI) paradigm experimentally produces an of ownership arm shift by simultaneously stroking in view participant’s visually occluded hand. aim this cross-over, placebo-controlled, single-blind study was to assess whether RHI, combination with high-frequency repetitive transcranial magnetic (rTMS) given as intermittent...
Submaximal ventilatory indices, i.e., point of optimal efficiency (POE) and anaerobic threshold (AT), are valuable indicators to assess the metabolic response during cardiopulmonary exercise testing (CPET). The order in which indices occur (ventilatory sequencing pattern, VISP), may yield additional information for interpretation CPET results intensity prescription. Therefore, we determined whether different VISP groups concerning POE AT exist. Additionally, analysed fat metabolism via...
In patients with non-alcoholic fatty liver disease (NAFLD) cardiovascular diseases are more often the cause of death than itself. However, prevalence atherosclerotic manifestations in individuals NAFLD is still uncertain. This study aimed to explore association between and coronary artery calcification (CAC) a Central European population.A total 1,743 participants from Paracelsus 10,000 were included. The underwent CAC scoring assessed for index (FLI), fibrosing steatohepatitis Index (FNI)...
Abstract Background Alzheimer disease (AD) worsens naming abilities as the progresses. It is argued that traditional tests, commonly used to aid in staging AD severity, may overestimate semantic abilities. This study explored whether a more challenging task can distinguish between healthy adults and those with amnestic mild cognitive impairment (aMCI) or AD. Method In cross‐sectional study, 16 individuals aMCI, 15 AD, 20 controls (see Table 1 for demographic details) performed rapid...