A5029885344- Metabolism and Genetic Disorders
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Ocular Surface and Contact Lens
- Allergic Rhinitis and Sensitization
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Organ Donation and Transplantation
- Neuroscience and Neural Engineering
- Multiple Sclerosis Research Studies
- Muscle activation and electromyography studies
- Pharmacological Effects and Toxicity Studies
- Biomedical Research and Pathophysiology
- Retinal Imaging and Analysis
- Epilepsy research and treatment
- Potassium and Related Disorders
- Drug-Induced Hepatotoxicity and Protection
- Ion Transport and Channel Regulation
- Renal function and acid-base balance
- Orthopaedic implants and arthroplasty
- Magnesium in Health and Disease
- Neurological Complications and Syndromes
- Renal and Vascular Pathologies
- Pancreatic function and diabetes
- Xenotransplantation and immune response
RWTH Aachen University
2022
University of Potsdam
2020
Heinrich Heine University Düsseldorf
2013-2018
Bielefeld University
2017
Düsseldorf University Hospital
2014-2017
Augenklinik Universitätsklinikum Würzburg
2016
Charité - Universitätsmedizin Berlin
1979-2015
Ambulatory Rehabilitation Center Berlin Adlershof
2013
Heidelberg University
2003-2011
Orthopädische Universitätsklinik
2007-2009
Plasma exchange (PE) is used for blood purification to modulate proteins involved in pathological processes. As the number of patients receiving PE treatment and heterogeneity underlying diseases steadily increasing, we evaluated most frequent complications analyzed causes leading adverse reactions. 883 procedures 113 between years 2000 2006 were retrospectively with respect complications. Additionally, settings procedure identify high-risk respective settings. A total 226 reactions recorded...
Purpose Strategic entrepreneurship (SE) depicts the nexus of strategic management and entrepreneurship, suggesting that firms can create superior wealth when simultaneously pursuing advantage-seeking opportunity-seeking behavior. As rapid growth in SE research led to a multidisciplinary, scattered fragmented literature landscape, authors aim structure this field. Design/methodology/approach The employ bibliographic coupling review Findings identify describe five major streams with 15...
Abstract Allotransplant rejection is a T‐cell‐dependent reaction. Functional in vitro T‐cell assays are being used widely for donorrecipient matching bone marrow transplantation and have recently been some centres transplant monitoring. In order to assess tolerance induction after clinical transplantation, we measured the response of host against donor spleen cells 33 kidney patients before every 3 months over period 18 months. The reactivity was not significantly different any rejecting...
We investigated changes in lysozyme activity serum and urine of kidney-transplant patients, found that the production catabolism such patients differs markedly from normal subjects. Resumption graft function decreases high by increasing rate transplant; at same time, however, is inhibited therapy with azathioprine. Changes correlate well leukocyte count; thus its determination might be useful monitoring immunosuppression. The urinary excretion enzyme, although not specific to rejection, a...
ABSTRACT Tufted hair folliculitis (THF) is a rare disease which characterized by the emergence of multiple hairs from widely dilated follicular orifices surrounded an inflammatory infiltrate resulting in scarring alopecia. The pathogenesis not yet fully understood. Although colonization with Staphylococcus aureus could always be detected and systemic treatment antibiotics alone sufficient, this microorganism considered to play important role. Around 30 patients THF have been reported since...
Abstract Purpose Recent studies highlighted that early diabetic neurodegeneration is present before microvascular changes are visible. Retinal can decrease retinal layer thickness. We aimed to determine whether decreased thickness already in the time course of disease. Methods A cross‐sectional analysis patients and healthy adults from German Diabetes Study ( GDS , ClinicalTrials.gov Identifier number: CT 01055093, https://clinicaltrials.gov/ct2/show/NCT01055093 ). Inclusion criteria were a...
SARS-CoV-2 was first detected in 2019 Wuhan, China. It has been found to be the most pathogenic virus among coronaviruses and is associated with endothelial damage resulting respiratory failure. Determine whether heparanase heparan sulfate fragments, biomarkers of function, can assist risk stratification clinical management critically ill COVID-19 patients admitted intensive care unit. We investigated 53 severe between March April 2020 University Hospital RWTH Aachen. Heparanase activity...
Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
We determined the urinary excretion of enzymes aminopeptidase (EC 3.4.11.2), alkaline phosphatase 3.1.3.1), gamma-glutamyltransferase 2.3.2.2), and N-acetyl-beta-glucosaminidase 3.2.1.30) in two groups renal-transplant recipients at different times after transplantation (1.8 months 52 months, respectively). Both patients showed a higher rate enzyme than did reference group healthy persons. More were excreted during early period later. The time-dependence was confirmed six studied course 15...
Slipped capital femoral epiphysis (SCFE) represents the most common disorder of hip in adolescents and a preliminary stage degenerative joint disease. Up to now, functional outcome evaluation measured by objective instruments has been commonly neglected. The present study investigates whether pathoanatomy after SCFE-analyzed on standard X-ray-match results gained three-dimensional gait analysis. A variation depending radiological findings growth arrest is hypothesized.Thirty-seven SCFE...
Objective: The aim of the present study was to compare preventive impact treatment with a vasopeptidase inhibitor (VPI) an angiotensin-receptor blocker (ARB) on left ventricular (LV) function and renal damage in rats failure after 5/6 ablation (Nx).Methods: Rats (n = 15–20, each group) underwent either sham-operation (Sham) or (Nx). Two additional groups Nx-animals (groups Nx-VPI Nx-ARB) were treated VPI ilepatril (AVE7688, 30 mg kg−1 d−1) ARB olmesartan (10 d−1). Animals followed for 4...
Work capacity is a major outcome variable in cardiological rehabilitation. However, there lacks of capacious and economic assessment instruments for work capacity. By developing item response theory based banks first step to close this gap done. The present study aims validate the cardiovascular rehabilitation inpatients (WCIB-Cardio) sample outpatients. Additionally, we examined differences between in- outpatients with regard their capacity.Data 283 77 were collected 15 centres. WCIB-Cardio...