A5101601306- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Esophageal Cancer Research and Treatment
- Sexual function and dysfunction studies
- Nutrition and Health in Aging
- Esophageal and GI Pathology
- Head and Neck Surgical Oncology
- Sexuality, Behavior, and Technology
- Cancer, Lipids, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer-related molecular mechanisms research
- Sexual Differentiation and Disorders
- MRI in cancer diagnosis
- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Salivary Gland Tumors Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Clinical Nutrition and Gastroenterology
- Cardiac, Anesthesia and Surgical Outcomes
- Hip and Femur Fractures
- Gastrointestinal motility and disorders
- Hepatitis B Virus Studies
- Lung Cancer Treatments and Mutations
- Hormonal and reproductive studies
First People’s Hospital of Jingmen
2025
Northwest A&F University
2025
Sinopec (China)
2025
Jinhua Central Hospital
2025
Zhejiang University
2025
Sichuan University
2025
Sun Yat-sen University Cancer Center
2021-2024
Sun Yat-sen University
2021-2024
Union Hospital
2024
Huazhong University of Science and Technology
2024
Abstract Background & aims Sarcopenia is associated with poor clinical outcomes of patients who underwent esophagectomy. The current diagnostic criteria for sarcopenia are complex and laborious. We aimed to employ the simple economic indicator index (SI = creatinine/cystatin C ×100) screen evaluate its prognostic value in esophageal cancer (EC). Methods Older participants National health nutrition examination survey (NHANES) database (1999–2002) were divided into three groups according...
Apolipoprotein E (ApoE), encoded by the ApoE gene (APOE), influences outcomes of traumatic brain injury (TBI), but mechanism remains unclear. The present study aimed to investigate effects different ApoEs on outcome TBI and explore possible mechanisms. Controlled cortical impact (CCI) was performed APOEε3 (E3) APOEε4 (E4) transgenic mice, APOE-KO (KO) wild type (WT) mice construct an in vivo model. Neurological deficits, blood barrier (BBB) permeability edema were detected at days 1, 3, 7...
ABSTRACT Background The rapid assessment of the conditions is crucial for prognosis atrial fibrillation (AF) patients admitted to emergency department (ED). We aim derive and validate a more accurate simplified scoring model optimize triage AF in ED. Materials Methods conducted retrospective study using data from Medical Information Mart Intensive Care (MIMIC‐IV) database developed models employing Random Forest algorithm. area under receiver operating characteristic (ROC) curve (AUC) was...
Shale formations display heterogeneous characteristics, and the current methods for assessing stability of adjacent wells using drilling data have limitations. This paper presents a regional wellbore prediction method shale geomechanics, with case study on Longmaxi formation in Yongchuan area. A 3D structural model was constructed seismic incorporated into finite element software to replicate mechanical parameters. Numerical simulations were employed determine situ stress predict fracture...
Addressing the escalating global burdens of inflammatory bowel disease and antimicrobial resistance demanded innovative food-based approaches to fortify gut health suppress pathogens. We introduced a novel edible probiotic, Enterococcus faecalis HY0110, isolated from marine Thunnus thynnus. Through comprehensive in vitro, vivo, metabolomic analyses, we demonstrated its superior antibacterial effects compared Lactobacillus rhamnosus GG, along with significantly enhanced antioxidant...
BACKGROUND:This study investigated the effect and mechanism of notoginsenoside R1 (NGR1) on chronic atrophic gastritis (CAG) in a rat model. MATERIAL AND METHODS:To perform our investigation, model CAG was established, then rats were treated with various doses NGR1. After treatment, hematoxylin-eosin (HE) staining used for histopathological observation further scoring. Enzyme-linked immunosorbent assay (ELISA) to determine contents gastrointestinal hormones, inflammatory factors, gastric...
Abstract Objectives Prognoses for nasopharyngeal carcinoma (NPC) between categories T2 and T3 in the Eighth American Joint Committee on Cancer (AJCC) staging system were overlapped. We explored value of skull base invasion (SBI) subclassification prognostic stratification use induction chemotherapy (IC) to optimize T2/T3 categorization NPC patients. Methods retrospectively reviewed 1752 patients from two hospitals. Eight bone structures evaluated. Survival differences compared slight SBI (T3...
Background The transplantation of adipose-derived stem cells (ASCs) is a most promising treatment for diabetic erectile dysfunction (DMED). However, the effect high glucose on post-transplantation survival limits efficacy ASCs transplantation. Prolonging time in vivo after key issue utilization DMED. Herein, we aimed to investigate therapeutic by downregulating NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) as well its mechanism action Methods were obtained isolating subcutaneous...
This study aimed to compare the efficacy and safety between transarterial chemoembolization (TACE) with CalliSpheres® microspheres (CSM-TACE) conventional TACE (cTACE) in patients hepatocellular carcinoma (HCC). Three hundred thirty-five HCC receiving CSM-TACE or cTACE were consecutively enrolled this multi-center, retrospective cohort study, then divided into group accordingly. Complete response (CR), objective (ORR) disease control (DCR) was assessed according mRECIST criteria at 1 month...
Importance Hepatitis B surface antigen (HBsAg) reportedly increases the risk of distant metastasis among patients with nasopharyngeal carcinoma (NPC). However, associated potential interaction and changes in hazard ratios (HRs) between HBsAg different plasma Epstein-Barr (EBV) DNA levels are unknown. Moreover, HBsAg-positive–associated NPC metastatic mechanism remains unclear. Objective To investigate prognostic value biological associations EBV on NPC. Design, Setting, Participants...
The prognostic stratification for oral tongue squamous cell carcinoma (OTSCC) is heavily based on postoperative pathological depth of invasion (pDOI). This study aims to propose a preoperative MR T-staging system tumor size non-pT4 OTSCC.
Accurate prediction of the prognosis nasopharyngeal carcinoma (NPC) is important for treatment. Lymph nodes metastasis an predictor distant failure and regional recurrence in patients with NPC. Traditionally, subjective radiological evaluation increases concerns regarding accuracy consistency predictions. Radiomics objective quantitative algorithm medical images. This retrospective analysis was conducted based on data 729 newly diagnosed NPC without metastases to evaluate performance...
Gastrointestinal symptoms constitute a frequent complication in postoperative patients with valvular heart disease (VHD), impacting their recovery. Probiotics contribute to regulating human gut microbiota balance and alleviating gastrointestinal symptoms. Our objective involved assessing the potential of Bifidobacterium animalis subsp. lactis LPL-RH alleviate expedite patient Adult diagnosed VHD scheduled for valve surgery were enrolled. 110 randomly divided into two groups received or...
Purpose: Traditional prognostic studies utilized different cut-off values, without evaluating potential information contained in inflammation-related hematological indicators. Using the interpretable machine-learning algorithm RuleFit, this study aimed to explore valuable inflammatory rules reflecting prognosis nasopharyngeal carcinoma (NPC) patients. Patients and Methods: In total, 1706 biopsy-proven NPC patients treated two independent hospitals (1320 386) between January 2010 March 2014...
Backgrounds Trimodal therapy (neoadjuvant chemoradiotherapy followed by esophagectomy) for locally advanced esophageal squamous cell carcinoma (ESCC) is associated with a significant survival benefit. Modified Ryan score an effective tool to evaluated the tumor regression grade (TRG) after neoadjuvant therapy. The aim of this study was evaluate prognostic value TRG overall (OS) and disease-free (DFS) in ESCC patients undergoing chemoradiation. Methods retrospectively reviewed 523 who...
Malnutrition is highly prevalent in critically ill patients. The modified Nutrition Risk the Critically (mNUTRIC) score has been introduced to evaluate nutritional risk of patients an intensive care unit (ICU). mNUTRIC a predictive factor mortality for medical or mixed ICU, whereas relationship between and prognosis cardiothoracic surgery recovery (CSRU) unclear related researches are limited.We conducted this retrospective cohort study explore value CSRU We identified totally 4059 from...