Jing Shen

ORCID: 0000-0002-5386-9880
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Psychosomatic Disorders and Their Treatments
  • Acute Ischemic Stroke Management
  • Pain Mechanisms and Treatments
  • Diabetes and associated disorders
  • Cardiac Arrhythmias and Treatments
  • Neurological and metabolic disorders
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Mental Health and Psychiatry
  • Atrial Fibrillation Management and Outcomes
  • Lipid metabolism and disorders
  • Acupuncture Treatment Research Studies
  • Neurological Disorders and Treatments
  • Schizophrenia research and treatment
  • Genetics and Neurodevelopmental Disorders
  • Retinal Diseases and Treatments
  • Metabolism, Diabetes, and Cancer
  • Cardiovascular Health and Risk Factors
  • Parkinson's Disease Mechanisms and Treatments
  • Clinical practice guidelines implementation
  • Sarcoidosis and Beryllium Toxicity Research
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Laser Applications in Dentistry and Medicine
  • Retinal Imaging and Analysis
  • Infectious Diseases and Tuberculosis
  • Venous Thromboembolism Diagnosis and Management

First Affiliated Hospital of Shihezi University Medical College
2022-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2023

Peking Union Medical College Hospital
2023

Union Hospital
2020-2022

Huazhong University of Science and Technology
2020-2022

Shihezi University
2020-2021

Nanfang Hospital
2020

Southern Medical University
2020

Affiliated Zhongshan Hospital of Dalian University
2016-2020

University of Nebraska–Lincoln
2017

Parkinson's disease (PD) is a widespread neurodegenerative condition [1]; however, its association with glycolysis, specifically the activity of genes related to has not yet been explored. We downloaded 3 datasets PD from GEO database and identified glycolytic PD. Subsequently, GO KEGG enrichment analyses were conducted. constructed diagnosis model using SVM algorithm for differentially expressed glycolysis-related verified LASSO regression analysis. Next, we regulatory network that respect...

10.1016/j.heliyon.2025.e41831 article EN cc-by-nc-nd Heliyon 2025-01-18

Abstract Loss of functional beta-cells is fundamental in both type 1 and 2 diabetes. In situ beta-cell regeneration therefore has garnered great interest as an approach to diabetes therapy. Here, after elimination pre-existing beta cells by a single high-dose streptozotocin (STZ), we demonstrated that considerable amount beta-like-cells was generated within 48 hrs. But the newly formed insulin producing failed respond glucose challenge at this time diminished afterwards. Insulin treatment...

10.1038/srep11703 article EN cc-by Scientific Reports 2015-07-01

Abstract Introduction Admission hyperglycemia is a common finding after spontaneous intracerebral hemorrhage (ICH) secondary to pre‐existing diabetes mellitus (DM) or stress‐induced (SIH). Studies of the causal relationship between SIH and ICH outcomes are rare. Aim We aimed identify whether DM was cause admission associated with outcomes. Methods glycosylated hemoglobin (HbA1c), glucose levels, comorbidity data from prospective, multicenter cohort, Chinese Cerebral Hemorrhage: Mechanisms...

10.1111/cns.14033 article EN cc-by CNS Neuroscience & Therapeutics 2022-11-29

Abstract Aims To determine if diabetic lipaemia is caused by loss of function mutations in the lipoprotein lipase gene, LPL . Methods We conducted a case–control study over 2 years two tertiary care hospitals South Australia. Six patients with history and 12 control subjects, previous ketoacidosis peak triglyceride concentrations < 2.4 mmol/l were included. Participants well at time investigations. Results Only one patient had mutation no functional APOC or GPIHBP 1 identified. The mean...

10.1111/dme.12565 article EN Diabetic Medicine 2014-08-16

This study demonstrates that the co-administration of lipopolysaccharide (LPS) and tumor necrosis factor-alpha (TNF-alpha) (LPS/TNF-alpha) can induce expression inducible nitric oxide synthase (iNOS), which results in generation apoptosis cultured human nasal microvascular endothelial cells (HNMECs). Since LPS TNF-alpha have been suggested to play an important role pathophysiology disease, we conclude leakage may therefore contribute inflammatory process such as allergic rhinitis asthma.The...

10.1080/00016480701361962 article EN Acta Oto-Laryngologica 2007-12-25

Nonablative laser has been used for the treatment and prevention of skin aging many years. Although mechanism not elucidated, histological evaluation showed that dermal fibroblasts its collagen production should be main target this rejuvenation. In order to determine effects a 1320 nm nonablative on human fibroblasts, two secretion factors, basic fibroblast growth factor (bFGF) transforming β1(TGF-β1), in vitro were detected.The cultured irradiated with at dose 15, 20, 24 J/cm(2)...

10.1111/j.1600-0846.2011.00525.x article EN Skin Research and Technology 2011-06-28

Abstract Background Physicians' knowledge and practice of atrial fibrillation (AF) are determinants the efficacy thromboprophylaxis. Hypothesis This study aimed to investigate physicians' knowledge, attitude, toward AF, analyze influencing factors, provide data support departments that develop health policies. Methods A cross‐sectional was carried out from October 1, 2016, March 31, 2018. standard‐structured anonymous questionnaire completed by each participant through face‐to‐face...

10.1002/clc.23361 article EN Clinical Cardiology 2020-03-24

In the ongoing fight against epidemic of COVID-19, medical staff has been under tremendous pressure. Wearing protective equipment (masks, goggles, and screens) with a poor breathability for long time causes various skin problems, such as allergies, excessive hydration, local mechanical injuries, even secondary infections. addition, in closed environment, compression friction aggravate reactions, which may compromise duty performance staff. It is therefore essential to provide timely...

10.12122/j.issn.1673-4254.2020.02.05 article EN Nanfang Yike Daxue xuebao 2020-02-29

Tuberculosis is one of the common chronic infectious diseases respiratory system in China, and presents high morbidity, drug resistance specific imaging characteristics. This paper focused on a case report atypical sarcoidosis which was misdiagnosed as tuberculosis before operation. CT discussed by contrast with clinical manifestations, aiming to survey differences between improve differential diagnosis.

10.1016/j.jrid.2016.01.005 article EN Radiology of Infectious Diseases 2016-01-07

Aims We aim to find out the factors affecting use of anticoagulants and intensity their choices, establish a basis for improving neurologists’ effective implementation guidelines. Methods A cross-sectional study is conducted in Hubei province central China. Each neurologist completes standard-structured anonymous questionnaire through face-to-face interviews. The problems include attitude options about anticoagulant therapy. Results total 611 neurologists from 38 hospitals respond this...

10.1111/ijcp.14305 article EN International Journal of Clinical Practice 2021-04-30
Coming Soon ...