A5084589933- Systemic Sclerosis and Related Diseases
- Viral gastroenteritis research and epidemiology
- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Molecular Biology Techniques and Applications
- Inflammasome and immune disorders
- Telomeres, Telomerase, and Senescence
- Muscle Physiology and Disorders
- Immune responses and vaccinations
- Brucella: diagnosis, epidemiology, treatment
- Exercise and Physiological Responses
- Transgenic Plants and Applications
- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- Atherosclerosis and Cardiovascular Diseases
- CRISPR and Genetic Engineering
- Immunodeficiency and Autoimmune Disorders
- T-cell and B-cell Immunology
- Animal Genetics and Reproduction
- Angiogenesis and VEGF in Cancer
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Clostridium difficile and Clostridium perfringens research
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Vitamin D Research Studies
Vita-Salute San Raffaele University
2023
IRCCS Ospedale San Raffaele
2023
Humanitas University
2020-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2022
University of Milano-Bicocca
2018
MultiMedica
2018
Ulcerative colitis (UC) is a chronic inflammatory disorder of unknown aetiology. Gut virome dysbiosis fundamental in UC progression, although its role the early phases disease far from fully understood. Therefore, we sought to investigate virome-associated protein encoded by
Abstract Duchenne muscular dystrophy (DMD) is a progressive severe muscle‐wasting disease caused by mutations in DMD , encoding dystrophin, that leads to loss of muscle function with cardiac/respiratory failure and premature death. Since dystrophic muscles are sensed infiltrating inflammatory cells gut microbial communities can cause immune dysregulation metabolic syndrome, we sought investigate whether intestinal bacteria support the response mdx murine model. We highlighted strong...
Therapies based on circulating proangiogenic cells (PACs) have shown promise in ischemic disease models but require further optimization to reach the bedside. Ischemia-associated hypoxia robustly increases microRNA-210 (miR-210) expression several cell types, including endothelial (ECs). In ECs, miR-210 represses EphrinA3 (EFNA3), inducing responses. This study provides new mechanistic evidences for a role of PACs. PACs were obtained from either adult peripheral blood or cord blood. was...
Severe early-onset erythroderma and gut inflammation, with massive tissue infiltration of oligoclonal activated T cells are the hallmark Omenn syndrome (OS).The impact altered homeostasis in cutaneous manifestations OS remains to be clarified.We analyzed a cohort 15 patients 129Sv/C57BL/6 knock-in Rag2R229Q/R229Q (Rag2R229Q) mouse model. Homing phenotypes circulating lymphocytes were by flow cytometry. Inflammatory cytokines chemokines examined sera ELISA skin biopsies immunohistochemistry...