A5070744215- Ammonia Synthesis and Nitrogen Reduction
- Advanced Photocatalysis Techniques
- CO2 Reduction Techniques and Catalysts
- Caching and Content Delivery
- Angiogenesis and VEGF in Cancer
- Electrocatalysts for Energy Conversion
- Covalent Organic Framework Applications
- MicroRNA in disease regulation
- Autophagy in Disease and Therapy
- Advanced Glycation End Products research
- Venous Thromboembolism Diagnosis and Management
- Cancer, Hypoxia, and Metabolism
- Atherosclerosis and Cardiovascular Diseases
- Sexual function and dysfunction studies
- Eicosanoids and Hypertension Pharmacology
- Inflammasome and immune disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Calpain Protease Function and Regulation
- Biomarkers in Disease Mechanisms
- Nanomaterials for catalytic reactions
- Circular RNAs in diseases
- Kruppel-like factors research
- Pregnancy and preeclampsia studies
- Inflammation biomarkers and pathways
- Catalytic Processes in Materials Science
Soochow University
2022-2025
Affiliated Hospital of Southwest Medical University
2016-2024
Nantong University
2022-2024
Southwest Medical University
2009-2022
Macau University of Science and Technology
2017
Hua Medicine (China)
2016
First Affiliated Hospital of Sichuan Medical University
2002-2016
The First Affiliated Hospital, Sun Yat-sen University
2011
Sun Yat-sen University
2011
Tangshan People's Hospital
2010
Abstract Electrochemical reduction of CO 2 (CO RR) and nitrogen (NRR) constitute alternatives to fossil fuel‐based technologies for the production high‐value‐added chemicals. Yet their practical application is still hampered by low energy Faradaic efficiencies although numerous efforts have been paid overcome fatal shortcomings. To date, most studies focused on designing developing advanced electrocatalysts, while understanding electrolyte, which would significantly influence reaction...
Electrochemical nitrogen reduction reaction (NRR) is a burgeoning field for green and sustainable ammonia production, in which numerous potential catalysts emerge endlessly. However, satisfactory performances are still not realized under practical applications due to the limited solubility sluggish diffusion of at interface. Herein, molecular imprinting technology adopted construct an adlayer with abundant imprints on electrocatalyst, capable selectively recognizing proactively aggregating...
Abstract Photoelectrochemical (PEC) technology offers new opportunities for pushing the renewable energy‐driven ammonia synthesis toward a practical level, while still facing unsatisfactory efficiency due to obstacle of dissociating inert nitrogen triple‐bonds. Herein, novel donor‐site‐acceptor system is constructed in covalent organic frameworks tackle this challenge highly efficient PEC synthesis. Highly active boron site elaborately embedded between donor and acceptor units, which can be...
Abstract Atherosclerosis is a multifactorial disease of the vasculature, and shear stress crucial regulator its process. Disturbed flow promotes atherosclerotic effects, while laminar has protective action on endothelium. Hippo/YAP major cascade that senses various mechanical cues mediates expression pro-inflammatory genes. However, mechanism modulating transcription factor YAP in response to different patterns blood remains unclear. In this study, we provide evidence modulates activity via...
Abstract Nowadays, gas‐involved electrochemical reactions, such as carbon dioxide reduction reaction (CO 2 RR), nitrogen (NRR), and hydrogen evolution (HER), have gradually become viable solutions to the global environmental pollution energy crisis. However, their further development is inseparable from in‐depth understanding of mechanisms, which are incredibly complicated cannot be satisfied by experiments alone. In this context, theoretical calculations simulations great significance in...
Abstract As the core of low‐temperature direct ammonia fuel cell (DAFC) technology, electrocatalytic oxidation reaction (AOR) has proven to be most active on platinum‐based catalysts. However, AOR is extremely surface sensitive that only Pt (200) facet exhibits high activity, whereas other facets usually do not make contributions. Herein, inert (220) PtMo nano‐alloy successfully awakened as one more in addition via directional single‐atom Ni‐doping. The introduction Ni triggers a targeted...
Electrocatalytic nitrogen reduction reaction offers a sustainable alternative to the conventional Haber-Bosch process. However, it is currently restricted by low effective overpotential due concentration polarization, which arises from accumulated products, ammonium, at interface. Here, novel covalent organic polymer with ordered periodic cationic sites proposed tackle this challenge. The whole network exhibits strong positive charge and effectively repels positively charged enabling an...
Low-temperature direct ammonia fuel cell (DAFC) stands out as a more secure technology than the hydrogen system, while there is still lack of elegant bottom-up synthesis procedures for efficient oxidation reaction (AOR) electrocatalysts. The widely accepted d-band center, even with consideration width, usually fails to describe variations in AOR reactivity many practical conditions, and accurate activity descriptor necessary less empirical path. Herein, upper edge, εu, derived from model,...
Previous studies reported that miR‐146a was involved in small intestine ischemia‐reperfusion (I/R) injury, but the mechanism is largely vague. Here, we aimed to identify change of patients with mesenteric ischemia and explore potential regulatory epithelial cells survival under I/R injury. The plasma 20 25 controls collected examine expression by qPCR. Rat intestinal (IEC‐6) 24 male Sprague–Dawley rats were included build model vitro vivo. qPCR results showed decreased both IEC‐6 rat tissues...
Diabetic nephropathy is the leading cause of kidney fibrosis. Recently, altered expressed or dysfunction some long non-coding RNAs (lncRNAs) has been linked to fibrosis; however, mechanisms lncRNAs in fibrosis remain unclear. We have shown that DPP-4 inhibitor linagliptin can inhibit endothelial-mesenchymal transition (EndMT) and ameliorate diabetic associated with protein levels via induction miR-29. Here, we found expression lncRNA H19 was significantly up-regulated TGF-β2-induced human...
Gas‐involved electrochemical reactions provide feasible solutions to the worldwide energy crisis and environmental pollution. It has been recognized that various elements of reaction system, including catalysts, intermediates, products, will undergo real‐time variations during process, which are significant meaning in‐depth understanding mechanisms, material structure, active sites. As judicious tools for monitoring changes in these complex elements, situ techniques have exposed spotlight...
The global nitrogen cycle has been destroyed by the quickly growing anthropogenic emissions of nitrite-containing pollutants during past decades, which causes numerous unexpected environmental side effects and threatens human health. Compared with conventional nitrite removal methods featuring low efficiency, high cost, secondary pollution, electrocatalytic reduction reaction garnered significant attention offers an appealing solution for recovering balance. Moreover, it takes a step further...
Electrochemical nitrate reduction reaction (NO3RR) stands out as a promising route for sustainable ammonia synthesis, in which active hydrogen (*H) plays crucial role both the deoxygenation and hydrogenation steps. However, regulation of surface *H is still overlooked, without intervention, competing evolution kinetically more favored over NO3RR, leaving current system far from satisfactory. Herein, based on reverse utilization Sabatier principle, series FexNiy substitutional solid-solution...
Hedgehog signaling plays critical roles in pancreatic oncogenesis and chronic pancreatitis, but its acute pancreatitis (AP) are largely ambiguous. In this study, we provide evidence that Sonic hedgehog (Shh), neither Desert (Dhh) nor Indian (Ihh), is the main protein whose expression activated during development of cerulein-induced mice, Shh serves as an anti-inflammation factor autocrine manner. Blocking with anti-Shh neutralizing antibody aggravates progression pancreatitis. Mechanistic...
Vascular calcification is a major complication of cardiovascular disease and chronic renal failure. Autophagy help to maintain stable internal external environment that important for modulating arteriosclerosis, but its pathogenic mechanism far from clear. Here, we aimed identify the bioactive compounds traditional Chinese medicines (TCM) exhibit an anti-arteriosclerosis effect. In β-glycerophosphate (β-GP)-stimulated human aortic smooth muscle cells (HASMCs), calcium level was increased...