A5062470847- Alkaloids: synthesis and pharmacology
- Neurotransmitter Receptor Influence on Behavior
- Prenatal Substance Exposure Effects
- Neurological Disease Mechanisms and Treatments
- Natural Antidiabetic Agents Studies
- Moyamoya disease diagnosis and treatment
- Ginseng Biological Effects and Applications
- Amino Acid Enzymes and Metabolism
- Biopolymer Synthesis and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Bioactive natural compounds
- Anesthesia and Neurotoxicity Research
- Tryptophan and brain disorders
- Ginkgo biloba and Cashew Applications
- Memory and Neural Mechanisms
- Chemical Synthesis and Analysis
First Affiliated Hospital of Nanchang University
2016-2023
Nanchang University
2016-2023
Southern Medical University
2013-2023
Xinqiao Hospital
2012
Army Medical University
2012
Mitogen-activated protein kinase (MAPK) signaling pathways are implicated in inflammatory and apoptotic processes of cerebral ischemia reperfusion (I/R) injury. Hence, MAPK represent a promising therapeutic target. Exploring the full potential inhibitors is useful strategy for ischemic stroke. Bilobalide, predominant sesquiterpene trilactone constituent Ginkgo biloba leaves, has been shown to exert powerful neuroprotective properties, which closely related both anti-inflammatory...
The present study investigated the insulin sensitivity, hypoglycemic, and hypolipidemic activities of ethanolic extract Mirabilis jalapa L. root (EEM) in normal diabetic mice. After induction diabetes with streptozotocin, both mice were singly or repeatedly for 28 days administrated EEM at doses 2, 4, 8 g/kg, respectively. Before diabetes, g/kg 14 injected streptozotocin continued on administration another days. Both after before repeated continually lowered blood glucose level, decreased...
Ethnopharmacological relevance: Uncaria rhynchophylla (Miq.) Miq. ex Havil. is a plant species that routinely devoted in traditional Chinese medicine to treat central nervous system disorders. Rhynchophylline (Rhy), predominant alkaloid isolated from Havil., has been demonstrated reverse methamphetamine-induced (METH-induced) conditioned place preference (CPP) effects mice, rats and zebrafish. The precise mechanism still poorly understood, thus further research necessary.Aim of study: This...
Objective To investigate the effects of poly-L-lysine different molecular weights on growth primary hippocampal neurons in neonatal rats.Methods The from rats were prepared with method extrusion by needle core; and then,the divided into three groups respectively planted culture plates where coated (no poly-L-lysine,70 000-150 000 150 000-300 000).The maintained Neurobasal-A medium without fetal bovine serum.The viewed at time points indentified neuron specificity enolization enzyme...